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Advanced melanoma survival rates improve significantly from 2013 to 2019, Dutch study finds

The change in overall survival (OS) among advanced melanoma patients diagnosed between 2013 and 2021.

14 Feb 2024

Understanding how natural genetic variation contributes to adaptive responses to low oxygen

Humans are still evolving, and Tatum Simonson, PhD, founder and co-director of the Center for Physiological Genomics of Low Oxygen at University of California School of Medicine, plans to use evolution to improve healthcare for all.

12 Feb 2024

New study finds 4’-fluorouridine effective against avian influenza in vitro and in vivo

A PLOS Pathogens study reveals 4’-fluorouridine effectively combats avian influenza in vitro and in animal models, showing promise as a treatment that overcomes resistance and reduces disease severity without significant adverse effects.

11 Feb 2024

Understanding the virological properties of SARS-CoV-2 variant JN.1

Since December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has posed a worldwide threat.

9 Feb 2024

Decoding the differences between two vital RNA transport complexes

Genetic expression, often leading to protein synthesis, requires a complex coordination of molecular machinery across several stages.

8 Feb 2024

Never-before-documented genetic disorder causes rare lung disease

The macrophage is one of the body's most important inhabitants. Meaning "big eater" in Greek, this immune cell consumes and digests problematic elements from microbes and cancer cells to dust and debris.

8 Feb 2024

New immunotherapy borrows cancer's tricks to unleash powerful T cells

Immunotherapies using engineered T cells have ushered in a new era in cancer treatment, but they have their limits. They may cause side effects or stop working, and they do not work at all against 90% of cancers.

8 Feb 2024

Parental traits offer new clues to predicting neurodevelopmental disorders in children

Predicting the trajectory of neurodevelopmental and psychiatric disorders like autism or schizophrenia is difficult because they can be influenced by many different genetic and environmental factors.

8 Feb 2024

Mitochondria on the move: New discovery could revolutionize treatment of brain diseases

The human brain is an organ that takes nearly from 20 to 25% of the energy the body needs. This high energy demand for neuronal functions depends on the transport and precise distribution of mitochondria — the energy-generating cell organelles — in each neuron.

7 Feb 2024

Promising influenza drug candidate shows activity against resistant variants

Influenza A viruses with induced resistance to a new candidate antiviral drug were found to be impaired in cell culture and weakened in animals, according to a study by researchers in the Center for Translational Antiviral Research at Georgia State University.

6 Feb 2024

Closing the Cancer Care Gap with the Power of Precision Oncology

According to American Cancer Society, Cancer causes about 1 in every 6 deaths globally, more than AIDS, tuberculosis, and malaria combined.

From MGI 5 Feb 2024

Small-molecule A485 mobilizes white blood cells on demand

New study reveals a small molecule that can selectively mobilize white blood cells, offering potential treatments for diseases with abnormal leukocyte counts.

3 Feb 2024

Researchers find new clue to treating aggressive Wilms tumor subtype

An international team, led by researchers at Nagoya University in Japan, may have determined why the diffuse anaplasia (DA) subtype of Wilms tumor (WT) resists chemotherapy.

2 Feb 2024

Combination drug treatment could be effective against malignant peripheral nerve sheath tumors

A combination of two cancer drugs could be effective against malignant peripheral nerve sheath tumors (MPNSTs) -; soft tissue tumors that are stubbornly resistant to chemotherapy and radiation -; according to a laboratory study led by researchers at the Johns Hopkins Kimmel Cancer Center.

31 Jan 2024

Scientists identify highly infectious, antibiotic-resistant E. coli strain in China

A new type of E. coli that is both highly infectious and resistant to some antibiotics has been discovered.

31 Jan 2024

Immune protein Ku70 key in fighting bowel cancer

Study establishes Ku70's role in tumor suppression, showing that reduced expression or mutations in this DNA repair protein significantly increase intestinal cancer risk.

30 Jan 2024

XRCC1 shows potential as a prognostic and immunological pan-cancer biomarker

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 1, entitled, "XRCC1: a potential prognostic and immunological biomarker in LGG based on systematic pan-cancer analysis."

30 Jan 2024

Mutation News and Research

Advanced melanoma survival rates improve significantly from 2013 to 2019, Dutch study finds

Understanding how natural genetic variation contributes to adaptive responses to low oxygen

New study finds 4’-fluorouridine effective against avian influenza in vitro and in vivo

Understanding the virological properties of SARS-CoV-2 variant JN.1

Decoding the differences between two vital RNA transport complexes

Never-before-documented genetic disorder causes rare lung disease

New immunotherapy borrows cancer's tricks to unleash powerful T cells

Parental traits offer new clues to predicting neurodevelopmental disorders in children

Mitochondria on the move: New discovery could revolutionize treatment of brain diseases

Promising influenza drug candidate shows activity against resistant variants

Closing the Cancer Care Gap with the Power of Precision Oncology

Small-molecule A485 mobilizes white blood cells on demand

Researchers find new clue to treating aggressive Wilms tumor subtype

Combination drug treatment could be effective against malignant peripheral nerve sheath tumors

Scientists identify highly infectious, antibiotic-resistant E. coli strain in China

Immune protein Ku70 key in fighting bowel cancer

XRCC1 shows potential as a prognostic and immunological pan-cancer biomarker

Genetic blueprint revealed: New insights into thyroid cancer's resistance and transformation

Improving mitochondrial metabolism could be a potential therapeutic target for Alzheimer's

RNA sequencing analysis feasible for diagnosis of molecular subtypes in pediatric B-ALL

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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