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Study reveals molecular changes in brain cells with Lewy bodies

A new study from Van Andel Institute scientists offers a first look into the complex molecular changes that occur in brain cells with Lewy bodies, which are key pathological hallmarks of Parkinson's disease and some dementias.

16 Apr 2024

MD Anderson and CureVac collaborate on mRNA-based cancer vaccines

The University of Texas MD Anderson Cancer Center and CureVac N.V. today announced a co-development and licensing agreement to develop novel mRNA-based cancer vaccines.

16 Apr 2024

Melatonin shows promise in preventing obesity, study finds

Two international studies led by the University of Granada (UGR) have confirmed that melatonin helps prevent obesity.

16 Apr 2024

The Lancet Breast Cancer Commission: Tackling inequalities, hidden costs, and empowering patients

Breast cancer is now the world's most common cancer; at the end of 2020, 7.8 million women were alive having been diagnosed in the previous five years.

16 Apr 2024

Insilico Medicine's AI-driven approach yields promising PTPN2/N1 inhibitor for cancer immunotherapy

In recent years, cancer immunotherapy, exemplified by PD-1 and its ligand PD-L1 blockade, has made remarkable advances.

13 Apr 2024

Metrion Biosciences enhances High Throughput Screening services with access to Enamine compound libraries

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From Metrion Biosciences Limited 11 Apr 2024

Three early-phase clinical studies show promising initial data for patients with lymphoma, gastric cancers

Three early-phase clinical studies presented by researchers from The University of Texas MD Anderson Cancer Center at the American Association for Cancer Research (AACR) Annual Meeting 2024 show promising initial data for patients with lymphoma, gastric or gastroesophageal junction cancers, and specific molecularly selected tumors.

10 Apr 2024

High blood levels of TMAO predicts chronic kidney disease risk in future

New findings from Cleveland Clinic and Tufts University researchers show high blood levels of TMAO (trimethylamine N-oxide) predicts future risk of developing chronic kidney disease over time.

9 Apr 2024

Revolutionary therapeutic shows promise for pancreatic cancer treatment

A new type of investigational therapeutic in development for pancreatic cancer has shown unprecedented tumor-fighting abilities in preclinical models of the disease, suggesting it has the potential to offer novel treatment options for nearly all pancreatic tumors, a comprehensive study has found.

8 Apr 2024

Burdock roots outshine dandelion in antidiabetic potential study

Study compares the antidiabetic potential of dandelion and burdock roots, finding burdock exhibits higher total phenolic content and α-amylase activity, while dandelion has higher total polysaccharide content, warranting further in vivo studies.

7 Apr 2024

Neural implants face ethical hurdles, study finds

Study delves into the ethical, design, and clinical trial challenges of AI-driven neural implants, highlighting the need for advancements in accuracy, user privacy, and societal acceptance.

7 Apr 2024

Human neuron model identifies potential therapeutic targets for Alzheimer's disease

Weill Cornell Medicine scientists have developed an innovative human neuron model that robustly simulates the spread of tau protein aggregates in the brain-;a process that drives cognitive decline in Alzheimer's disease and frontotemporal dementia.

5 Apr 2024

Novel combination therapy shows promise in difficult-to-treat endometrial cancer, study finds

In a small, investigator-initiated phase 2 study by Dana-Farber Cancer Institute investigators, a novel combination of an antibody-drug conjugate and an immune checkpoint inhibitor showed notable activity in pre-treated patients with a difficult-to-treat form of endometrial cancer.

5 Apr 2024

Adeno-associated virus: The gene therapy revolution faces manufacturing and safety hurdles

Recombinant adeno-associated virus (rAAV)-based genetic applications to treat human diseases.

5 Apr 2024

Non-invasive detection and treatment of ovarian cancer with new radiotheranostic system

A new radiotheranostic system has the ability to detect and treat ovarian cancer noninvasively, according to new research published in the April issue of The Journal of Nuclear Medicine.

4 Apr 2024

Even moderate alcohol use by pregnant patients may affect babies' prenatal development

University of New Mexico researchers have found that even low to moderate alcohol use by pregnant patients may contribute to subtle changes in their babies' prenatal development, including lower birth length and a shorter duration of gestation.

2 Apr 2024

To ban or not to ban, the case for reformulating ultra-processed foods

Despite concerns about ultra-processed foods (UPFs) and non-communicable diseases (NCDs), evidence of causality remains unclear; reformulating UPFs may offer significant health advantages.

1 Apr 2024

New immunotherapy strategy potentially lays the groundwork for treating autoimmune diseases

Mayo Clinic scientists have developed an immunotherapy strategy that potentially lays the groundwork for treating a spectrum of autoimmune diseases.

1 Apr 2024

Scientists develop trivalent vaccine offering broad protection against coronaviruses

Scientists have been searching for the optimal coronavirus vaccine since the Covid-19 pandemic started.

1 Apr 2024

UC San Diego researchers secure NIH grants to develop noninvasive immune cell imaging technology

Researchers at University of California San Diego School of Medicine have been awarded two new grants by the National Institutes of Health (NIH), totaling $6.7 million, to develop and clinically test technologies that can noninvasively examine and quantify immune cells found in tumors.

1 Apr 2024

Preclinical News and Research

Study reveals molecular changes in brain cells with Lewy bodies

MD Anderson and CureVac collaborate on mRNA-based cancer vaccines

Melatonin shows promise in preventing obesity, study finds

The Lancet Breast Cancer Commission: Tackling inequalities, hidden costs, and empowering patients

Insilico Medicine's AI-driven approach yields promising PTPN2/N1 inhibitor for cancer immunotherapy

Metrion Biosciences enhances High Throughput Screening services with access to Enamine compound libraries

Three early-phase clinical studies show promising initial data for patients with lymphoma, gastric cancers

High blood levels of TMAO predicts chronic kidney disease risk in future

Revolutionary therapeutic shows promise for pancreatic cancer treatment

Burdock roots outshine dandelion in antidiabetic potential study

Neural implants face ethical hurdles, study finds

Human neuron model identifies potential therapeutic targets for Alzheimer's disease

Novel combination therapy shows promise in difficult-to-treat endometrial cancer, study finds

Adeno-associated virus: The gene therapy revolution faces manufacturing and safety hurdles

Non-invasive detection and treatment of ovarian cancer with new radiotheranostic system

Even moderate alcohol use by pregnant patients may affect babies' prenatal development

To ban or not to ban, the case for reformulating ultra-processed foods

New immunotherapy strategy potentially lays the groundwork for treating autoimmune diseases

Scientists develop trivalent vaccine offering broad protection against coronaviruses

UC San Diego researchers secure NIH grants to develop noninvasive immune cell imaging technology

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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