Proteomics News and Research

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The term 'proteome' was first coined in 1994, and refers to all the proteins in a cell, tissue, or organism. Proteomics refers to the study of the proteome. Because proteins are involved in almost all biological activities, the proteome is a rich source of biological information.

Researchers identify novel biomarkers in renal cell carcinomas

A new study led by University of Michigan Health Rogel Cancer Center researchers identifies novel biomarkers in renal cell carcinomas.

6 May 2024

Unlocking glioblastoma's immune suppression mechanism

The Wistar Institute assistant professor Filippo Veglia, Ph.D., and team, have discovered a key mechanism of how glioblastoma -; a serious and often fatal brain cancer -; suppresses the immune system so that the tumor can grow unimpeded by the body's defenses.

3 May 2024

Study provides deeper understanding of how membrane remodeling works in human cells

In a study published in the prestigious scientific journal PNAS, Umeå researchers describe a natural product-like molecule, Tantalosin, that inhibits interaction between two proteins in complexes that reshape membranes inside the cell.

3 May 2024

Researchers identify key molecular alterations from endurance exercise that could combat chronic diseases

A whole-organism molecular map of the temporal effects of endurance training in rats.

3 May 2024

Protein profiling reveals impact of aging and resistance training on skeletal muscle proteome

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 8, entitled, "A novel deep proteomic approach in human skeletal muscle unveils distinct molecular signatures affected by aging and resistance training."

2 May 2024

Study reveals molecular changes in 19 organs due to exercise

The health benefits of exercise are well known but new research shows that the body's response to exercise is more complex and far-reaching than previously thought.

2 May 2024

New drug candidate reverses obesity in mice by transforming liver metabolism

A mitochondrial transcription inhibitor (IMT) shifted metabolism in high-fat diet mice toward fatty acid oxidation, leading to weight loss, reduced liver fat, and improved glucose tolerance.

1 May 2024

Study investigates senescent phenotypes of human corneal endothelial cells upon UV-A exposure

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 8, entitled, "Senescent characteristics of human corneal endothelial cells upon ultraviolet-A exposure."

30 Apr 2024

$4.8 million grant supports research on TDP-43 misfolding in neurodegenerative diseases

A new $4.8 million grant will support researchers from Indiana University School of Medicine and the Medical Research Council Laboratory of Molecular Biology to study how human neurodegenerative diseases are affected by the misfolding of the protein TDP-43.

23 Apr 2024

Longitudinal multi-omics monitoring paves the way for early pancreatic cancer diagnosis

A new case report published in the peer-reviewed OMICS: A Journal of Integrative Biology describes how longitudinal multi-omics monitoring (LMOM) helped to detect a precancerous pancreatic tumor and led to a successful surgical intervention.

23 Apr 2024

Adherence to the EAT-Lancet diet reduces the risk of heart failure

Adherence to the EAT-Lancet diet, rich in plant-based foods, is associated with a reduced risk of heart failure, potentially mediated by specific plasma proteins, in a large population-based cohort study.

8 Apr 2024

Pioneering vaccine strategy promises to outmaneuver antimicrobial resistance

Study introduces Reverse Vaccine Development as a strategic approach to identify correlates of protection early in vaccine development against antimicrobial-resistant pathogens, aiming to mitigate risks such as significant phase-III clinical trial failures.

7 Apr 2024

Research offers first insights into the mechanism behind synaptic development

The first analysis of how synaptic proteins change during early development reveals differences between mice and marmosets but also what's different in individuals with autism spectrum disorders.

28 Mar 2024

Study unveils protein signatures for early detection of endometrial cancer in cervico-vaginal fluid

Proteomic signatures in blood plasma and cervicovaginal fluid for endometrial cancer detection.

26 Mar 2024

Study reveals breakthrough in non-invasive detection of endometrial cancer

Study uncovers proteomic signatures in blood plasma and cervicovaginal fluid that could lead to non-invasive detection methods for endometrial cancer, demonstrating significant potential for early diagnosis and improved patient outcomes.

24 Mar 2024

Researchers shed light on proteins controlling the development of ovaries in mice

Researchers at the Francis Crick Institute have shed light on the proteins controlling the development of ovaries in mice before and after birth.

22 Mar 2024

Researchers identify novel protein biomarkers linked to coronary heart disease

Coronary heart disease is a major global health problem, especially among people with type 2 diabetes.

18 Mar 2024

Rapid Novor and MAbSilico partner for world's first AI-guided epitope mapping service for antibodies

Rapid Novor and MAbSilico partner to provide the world's first comprehensive AI-guided epitope mapping service. This service combines hydrogen-deuterium exchange mass spectrometry (HDX-MS) with advanced artificial intelligence (AI)-driven computational modeling.

From Rapid Novor Inc 18 Mar 2024

Scientists aim to understand why T cells do not sustain energy in tumors

T cells are often called "assassins" or "killers" because they can orchestrate and carry out missions to hunt down bacteria, viruses, and cancer cells throughout the body.

15 Mar 2024

Understanding how chikungunya virus affects the brain and body

The chikungunya virus, transmitted by Aedes aegypti and Aedes albopictus mosquitoes and responsible for more than 900 deaths in Brazil since it arrived around ten years ago, is capable of spreading through the blood, reaching multiple organs and crossing the blood-brain barrier, which protects the central nervous system.

12 Mar 2024

Proteomics News and Research

Further Reading

Researchers identify novel biomarkers in renal cell carcinomas

Unlocking glioblastoma's immune suppression mechanism

Study provides deeper understanding of how membrane remodeling works in human cells

Researchers identify key molecular alterations from endurance exercise that could combat chronic diseases

Protein profiling reveals impact of aging and resistance training on skeletal muscle proteome

Study reveals molecular changes in 19 organs due to exercise

New drug candidate reverses obesity in mice by transforming liver metabolism

Study investigates senescent phenotypes of human corneal endothelial cells upon UV-A exposure

$4.8 million grant supports research on TDP-43 misfolding in neurodegenerative diseases

Longitudinal multi-omics monitoring paves the way for early pancreatic cancer diagnosis

Adherence to the EAT-Lancet diet reduces the risk of heart failure

Pioneering vaccine strategy promises to outmaneuver antimicrobial resistance

Research offers first insights into the mechanism behind synaptic development

Study unveils protein signatures for early detection of endometrial cancer in cervico-vaginal fluid

Study reveals breakthrough in non-invasive detection of endometrial cancer

Researchers shed light on proteins controlling the development of ovaries in mice

Researchers identify novel protein biomarkers linked to coronary heart disease

Rapid Novor and MAbSilico partner for world's first AI-guided epitope mapping service for antibodies

Scientists aim to understand why T cells do not sustain energy in tumors

Understanding how chikungunya virus affects the brain and body

Omics eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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