Therapeutics News and Research

RSS

Deciphering the role of Th2-multipotent progenitor cells in chronic allergic inflammation

Currently, most therapies for allergic diseases require lifelong treatment. Allergic reactions, characterized by ongoing (type 2) inflammation in response to chronic antigen exposure, underlie many chronic diseases in humans, including asthma, atopic dermatitis, ulcerative colitis and more.

30 Apr 2024

Specific class of drugs can reverse diet-induced obesity, fatty liver and diabetes in mice

Researchers at Karolinska Institutet may have found a new way to treat obesity and related disorders by targeting the cells' powerhouses, the mitochondria.

30 Apr 2024

Asimov achieves 10x improvement in lentiviral production, launches new stable cell line development service

...

30 Apr 2024

Study reveals genetic divergence and drug resistance mechanisms in two critical superbugs

Infectious diseases caused by pathogenic strains of bacteria are a global cause of morbidity and mortality. Hospital-acquired infections caused by Klebsiella pneumonia and Pseudomonas aeruginosa were found vulnerable during the COVID-19 pandemic.

29 Apr 2024

Benefits and challenges of integrating nursing home residents into clinical trials

Clinical trials are constantly being designed and study participants enrolled to determine if medical treatments and therapies are safe and effective.

29 Apr 2024

Parkinson’s UK invests £2.1 million in Neumora Therapeutics for preclinical testing of new Parkinson’s drug

Parkinson’s UK is investing £2.1million to support Neumora Therapeutics to carry out preclinical testing of NMRA-NLRP3, a NLRP3 inhibitor with the potential to reduce inflammation and protect brain cells in Parkinson’s. NLRP3 is a protein that plays a role in regulating a number of inflammatory processes that are believed to contribute to the damage to brain cells that underlies Parkinson’s.

27 Apr 2024

Harnessing immune enhancement to combat drug-resistant tuberculosis

Experts are working on novel immune-enhancing therapies called host-directed therapies to use the body's own immune system to target tuberculosis, with hopes that they could tackle even the drug-resistant forms of the disease.

26 Apr 2024

New imaging technique provides a much closer look at fibril assemblies

A new imaging technique developed by engineers at Washington University in St. Louis can give scientists a much closer look at fibril assemblies, stacks of peptides like amyloid beta, most notably associated with Alzheimer's disease.

26 Apr 2024

Study suggests a common brain network exists between heart rate deceleration and depression

A new study by researchers at Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, suggests a common brain network exists between heart rate deceleration and depression.

26 Apr 2024

CASGEVY gene therapy eliminates vaso-occlusive crises in sickle cell patients

In a landmark study, an international consortium led by researchers at Children's Hospital of Philadelphia (CHOP) published the final results of a key clinical trial of the gene therapy CASGEVY (exagamglogene autotemcel) for the treatment of sickle cell disease in patients 12 years and older with recurrent vaso-occlusive crises (VOCs).

24 Apr 2024

NYU Langone surgeons perform first combined mechanical heart pump and gene-edited pig kidney transplant surgery

Surgeons at NYU Langone Health performed the first combined mechanical heart pump and gene-edited pig kidney transplant surgery.

24 Apr 2024

Global study reveals mismatch in COVID-19 treatment guidelines with WHO standards

Study assesses global discrepancies in COVID-19 management guidelines across WHO member states, revealing that many national guidelines do not fully align with WHO recommendations, especially in lower-resource countries.

23 Apr 2024

Analysis finds significant variations in national COVID-19 treatment recommendations

National clinical guidelines for the treatment of COVID-19 vary significantly around the world, with under-resourced countries the most likely to diverge from gold standard (World Health Organization; WHO) treatment recommendations, finds a comparative analysis published in the open access journal BMJ Global Health.

23 Apr 2024

Innovative malaria prodrug targets liver, enhances efficacy while reducing toxicity, preclinical studies show

Tafenoquine, a prodrug that could fulfill the criteria for a mass eradication campaign.

23 Apr 2024

CN Bio raises $21 million USD in first close of Series B investment round

Bayland Capital and founding shareholder, CN Innovations Holdings Ltd, to invest $10 M and $5.5 M, respectively. Investment will expand product development and scaling of the organization to meet increased demand for Organ-on-a-Chip (OOC) solutions.

23 Apr 2024

AI models fall short in medical coding accuracy

State-of-the-art artificial intelligence systems known as large language models (LLMs) are poor medical coders, according to researchers at the Icahn School of Medicine at Mount Sinai.

22 Apr 2024

Insightful review explores alcohol-related liver cancer pathogenesis

While heavy drinking is a well-established risk factor for liver cancer, the specific mechanisms by which alcohol contributes to A-HCC remain unclear.

22 Apr 2024

Top pharmaceutical company evaluates Optimer for precision liver medicine

Optimer delivery vehicle has been shipped to a pharma partner for external evaluation.

From Aptamer Group 22 Apr 2024

UCSF study identifies cells responsible for cough reflex

When a mouthful of water goes down the wrong pipe – heading toward a healthy person’s lungs instead of their gut – they start coughing uncontrollably.

18 Apr 2024

New urine-based test improves identification of high-grade prostate cancer

Researchers at the University of Michigan Rogel Cancer Center have developed a new urine-based test that addresses a major problem in prostate cancer: how to separate the slow-growing form of the disease unlikely to cause harm from more aggressive cancer that needs immediate treatment.

18 Apr 2024

Therapeutics News and Research

Deciphering the role of Th2-multipotent progenitor cells in chronic allergic inflammation

Specific class of drugs can reverse diet-induced obesity, fatty liver and diabetes in mice

Asimov achieves 10x improvement in lentiviral production, launches new stable cell line development service

Study reveals genetic divergence and drug resistance mechanisms in two critical superbugs

Benefits and challenges of integrating nursing home residents into clinical trials

Parkinson’s UK invests £2.1 million in Neumora Therapeutics for preclinical testing of new Parkinson’s drug

Harnessing immune enhancement to combat drug-resistant tuberculosis

New imaging technique provides a much closer look at fibril assemblies

Study suggests a common brain network exists between heart rate deceleration and depression

CASGEVY gene therapy eliminates vaso-occlusive crises in sickle cell patients

NYU Langone surgeons perform first combined mechanical heart pump and gene-edited pig kidney transplant surgery

Global study reveals mismatch in COVID-19 treatment guidelines with WHO standards

Analysis finds significant variations in national COVID-19 treatment recommendations

Innovative malaria prodrug targets liver, enhances efficacy while reducing toxicity, preclinical studies show

CN Bio raises $21 million USD in first close of Series B investment round

AI models fall short in medical coding accuracy

Insightful review explores alcohol-related liver cancer pathogenesis

Top pharmaceutical company evaluates Optimer for precision liver medicine

UCSF study identifies cells responsible for cough reflex

New urine-based test improves identification of high-grade prostate cancer

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest News