X-Pulse represents a key breakthrough in the versatility of benchtop NMR spectroscopy.
Its innovative modular design integrates fully tunable broadband X-nuclei capability, flow chemistry, reaction monitoring, sample automation, and variable temperature control, all while delivering exceptional spectral resolution. X-Pulse offers the broadest range of NMR chemical analysis, making it ideal for research, development, quality control, and teaching directly at your laboratory bench.
The X-Pulse benchtop NMR spectrometer is designed to identify structures, characterize reaction dynamics, and measure the physical and chemical properties of molecules, compounds, and mixtures. It can be easily installed in a laboratory without the need for liquid cryogens, thanks to its high homogeneity permanent magnet that provides exceptional temperature stability.
X-Pulse is compatible with standard 5 mm NMR tubes and features an easy-to-use flow cell. The optional X-Auto sample changer enhances throughput and automates data acquisition for up to 25 samples.
The newly enhanced SpinFlow software simplifies routine experiments and offers greater flexibility for advanced users.
For coherence selection, selective excitation, and effective water and solvent suppression, X-Pulse includes comprehensive pulsed field gradients and shaped RF pulses as standard features.
On resonance: In Conversation with Dr Dave Ellis
Video Credit: Oxford Instruments Magnetic Resonance
Video Credit: Oxford Instruments Magnetic Resonance
Broadband
The only broadband benchtop NMR system in the world, X-Pulse, allows users to freely switch between a variety of X-Nuclei with just one benchtop NMR instrument.
- Easy to use
- Flow NMR option
- Resolution <0.35 Hz (50 %)/<10 Hz (0.55 %)
- Sensitivity: 130:1 for 1 % Ethyl Benzene
- Pulsed field gradients as standard (>0.5 T/m)
- No cryogens
- Standard 5 mm OD NMR tubes
- Variable temperature option (0 °C – 65 °C)
- X-Channel: fully tuneable ²⁹Si – ³¹P
Image Credit: Oxford Instruments Magnetic Resonance
Dual X
The X-Pulse Dual-X benchtop NMR system allows for the analysis of four NMR active nuclei using a single device.
- Resolution <0.35 Hz (50 %) / <10 Hz (0.55 %)
- Sensitivity: 130:1 for 1 % Ethyl Benzene
- Pulsed field gradients as standard (>0.5T/m)
- X-Channel: select 2 nuclei from ¹³C, ³¹P, ⁷Li, ²⁹Si,¹¹B, ²³Na, and more
- Variable temperature option (0 °C – 65 °C)
- Easy to use
- Flow NMR option
- No cryogens
- Standard 5mm OD NMR tubes
- Fully upgradable to X-Pulse broadband
Image Credit: Oxford Instruments Magnetic Resonance
HF
The HF is a single channel benchtop NMR system with outstanding sensitivity.
- Resolution <0.35 Hz (50 %)/<10 Hz (0.55 %)
- Sensitivity: 200:1 for 1 % Ethyl Benzene
- Pulsed field gradients as standard (>0.5 T/m)
- Variable temperature option (0 °C – 65 °C)
- Flow NMR option
- No cryogens
- Easy to use
- Standard 5mm OD NMR tubes
- Fully upgradable to X-Pulse broadband or X-Pulse Dual-X
Image Credit: Oxford Instruments Magnetic Resonance
Choose the nuclei
True broadband capability with X-Pulse provides the flexibility to select the nuclei you need for your experiments, whether it is ¹H, ³C, ³P, ⁷Li, ²⁹Si, or more exotic options like ²⁹Xe, ¹B, or ⁵⁹Co, because true broadband capability allows to do freely. imply choose the desired nucleus in the software and adjust the probe to operate under optimal conditions.
Maximizing the signal-to-noise ratio is crucial for the success of benchtop NMR experiments. The exceptional sensitivity of X-Pulse, achieving 130:1 (broadband/Dual-X) and 200:1 (HF) for 1% ethyl benzene, makes successful outcomes more achievable. For nuclei with low receptivity, such as ¹³C or ²⁹Si, ensuring sensitivity is essential. The ability to tune and match for each specific nucleus allows users to achieve the maximum signal-to-noise ratio.
Image Credit: Oxford Instruments Magnetic Resonance
Powerful
X-Pulse is a highly versatile and powerful benchtop NMR instrument. Its design philosophy, which separates the magnet and electronics akin to high-field NMR systems, ensures optimal performance of key components independently.
This approach allows X-Pulse to handle a vast array of NMR pulse sequences, from standard 1-dimensional and 2-dimensional proton and X-nuclei experiments like FID, DEPT, HSQC, and HMBC, to more intricate sequences such as gs-HSQC, PGSE, and solvent suppression, utilizing 3-axis pulsed field gradients and shaped pulses.
These robust NMR techniques can be combined with additional instrument capabilities, such as the flow cell for in-line reaction monitoring and the variable temperature system, enabling users to gain comprehensive insights into their chemistry within the lab.
Image Credit: Oxford Instruments Magnetic Resonance
High resolution
With X-Pulse, NMR peaks are easier to separate, and lower concentrations become visible. X-Pulse utilizes a 60 MHz (1.4 T) permanent magnet. Its new shimming technology generates an extremely homogeneous field, delivering a resolution of less than 0.35 Hz at half-height and a line shape of 10 Hz at 0.55 %. Peaks are easier to identify and integrate. Combined with shaped RF pulses, solvent suppression is much more effective, allowing even challenging compounds such as sugars and starches dissolved in water to be analyzed.
Image Credit: Oxford Instruments Magnetic Resonance
Benchtop convenience
The magnetic field of an X-Pulse benchtop NMR system is produced using a uniquely designed permanent magnet. This eliminates the need for cryogens to cool the system, significantly reducing running costs and concerns about magnet quenching.
This unique magnet design delivers extremely high stability, ensuring that experiments are artefact-free. The benchtop footprint and minimal stray field (2 G line within the magnet case) allow X-Pulse to be installed in a wide range of environments without the need for special facilities.
NMR can be performed right next to experiments in the lab or even next to a process reactor, allowing for better understanding of reaction processes. The large thermal mass of the magnet ensures stable, artefact-free data collection, whether flowing liquids at 10 °C or 75 °C through the flow cell. Additionally, the optional X-Pulse mobile workstation allows for easy movement of the system.
Image Credit: Oxford Instruments Magnetic Resonance
Easy operation
The new SpinFlow benchtop NMR data acquisition software brings a new level of ease of use to X-Pulse. Predefined “quick" experiments enable the collection of routine data, such as a basic 1-dimensional ¹H spectrum or a ¹³C DEPT array, with a single click.
Any experiment setup can be turned into a single-click experiment with the user-defined experiments feature. This allows experienced users to save their own sequences and parameters for future use, ensuring consistency and reducing the time required to collect data. Experiment queues can be easily built and saved, automating multiple acquisitions on a sample and repeating that process across many samples to maximize efficiency and minimize errors.
Image Credit: Oxford Instruments Magnetic Resonance
See X-Pulse in action
New X-Pulse with X-Auto
Video Credit: Oxford Instruments Magnetic Resonance
Related applications
- Agriculture and Food
- Batteries
- Chemistry Research
- Chemical Manufacturing
- Illicit Drugs Testing
- Pharma
- Polymers
- Teaching NMR