Cell Biology

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Macrophage-targeted therapy could enhance cardiac regeneration and myocardial repair

A new review published in Genes & Diseases highlights macrophage-targeted therapy as a promising frontier in cardiac regeneration and myocardial repair.

5 Mar 2025

Study links environmental chemical exposures to faster biological aging

A new research paper was published in Aging (Aging-US) on February 11, 2025, Volume 17, Issue 2, titled "Exposome-wide association study of environmental chemical exposures and epigenetic aging in the national health and nutrition examination survey."

5 Mar 2025

Brown fat discovery could revolutionize aging and exercise performance

Rutgers Health researchers have made discoveries about brown fat that may open a new path to helping people stay physically fit as they age.

5 Mar 2025

New insights into how white blood cells clear pathogens

A vivid new image is taking shape in the world of cell biology: Imagine bacteria adhering to the surface of a cell, perhaps at the site of an injury or wound.

4 Mar 2025

Researchers discover neural mechanism behind leptin resistance and a way to reverse it

Worldwide obesity rates have more than doubled since 1990, with nearly a billion people now falling into the category.

4 Mar 2025

Researchers uncover key biological mechanism that prevents sperm-egg fusion

A Yale-led research team has uncovered how a naturally occurring biological mechanism found in mammals is able to prevent sperm cells from interacting with an egg, preventing fertilization.

3 Mar 2025

Study unveils protein complex critical for sperm morphology

The human body is full of checks and balances that ensure correct growth, development, and function of all our different systems. Now, researchers from Japan have reported a newly discovered protein interaction that regulates sperm development.

3 Mar 2025

Synthetic microbiome therapy offers new hope against C. difficile infections

A synthetic microbiome therapy, tested in mice, protects against severe symptoms of a gut infection that is notoriously difficult-to-treat and potentially life threatening in humans, according to a team of researchers at Penn State.

3 Mar 2025

Study elucidates mechanism behind bacterial cancer therapy

A research team led by Prof. Liu Chenli from the Shenzhen Institutes of Advanced Technology of the Chinese Academy of Sciences (CAS) and Prof. Xiao Yichuan from the Shanghai Institute of Nutrition and Health of CAS elucidated the mechanism behind bacterial cancer therapy using a genetically engineered bacterial strain.

3 Mar 2025

Study elucidates mechanism connecting ER membrane remodeling to pyroptosis in cancer cells

Pyroptosis, a highly inflammatory type of programmed cell death, has garnered attention for its potential in cancer treatment.

3 Mar 2025

St. Jude scientists discover how retinoic acid selectively kills metastatic neuroblastoma cells

Neuroblastoma is a solid tumor that occurs in children. When high-risk, the disease has a poor prognosis. Decades ago, adding the drug retinoic acid to neuroblastoma treatment increased survival by 10-15%.

2 Mar 2025

Innovative AI-enabled, low-cost device makes flow cytometry accessible for clinical use

A team of researchers at the George R. Brown School of Engineering and Computing at Rice University has developed an innovative artificial intelligence (AI)-enabled, low-cost device that will make flow cytometry ⎯ a technique used to analyze cells or particles in a fluid using a laser beam ⎯ affordable and accessible.

2 Mar 2025

UCSF study reveals lungs as source of hematopoietic stem cells

Red blood cells carry oxygen from the lungs to every other organ, and blood-forming stem cells must make about 200 billion new red blood cells each day to keep the oxygen flowing.

28 Feb 2025

Trained immunity may exacerbate inflammatory bone loss disorders

Clinical research has long focused on ways to harness the actions of the immune system. From vaccines to immunotherapies, researchers have used their knowledge of the immune system to develop therapies to treat or prevent diseases from influenza to autoimmune disease and cancer.

27 Feb 2025

Macrophages use bacteria to build vital nutrients and control inflammation

Immune cells that eat bacteria in the body don't stash them in specialized compartments as once thought, but turn them into critical nutrients that build proteins, create energy and keep the cells alive, according to a new study from scientists at the University of Colorado Anschutz Medical Campus.

27 Feb 2025