Cell Biology

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Study reveals new insight into how human telomeres function at the molecular level

The length of telomeres that protect the ends of our chromosomes should be tightly regulated. Those that are too long predispose to cancer, and those that are too short lose their protective ability, resulting in telomere disorders with serious health consequences.

4 Jun 2024

Understanding the role of tumor-associated fibrosis in immunotherapy resistance

Immunotherapy is based on harnessing a person's own immune system to attack cancer cells.

4 Jun 2024

Unraveling the role of follicular helper lymphocytes in antibody production against viruses and allergies

The production of antibodies, essential for protecting our body against infections, is very well regulated through the action of a specific subtype of immune system cells, follicular helper lymphocytes.

4 Jun 2024

Proteomic profiling reveals sexual dimorphism and immune system alterations in Werner syndrome

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 10, entitled, "Integrated liver and serum proteomics uncover sexual dimorphism and alteration of several immune response proteins in an aging Werner syndrome mouse model."

4 Jun 2024

Applied Cells releases game-changing reagent kits to empower cell therapy development

Applied Cells is excited to announce the launch of its MARS® Ingenuity™ Reagent kits for fast and easy cell isolation. This innovative product line features both RUO and GMP-grade reagents, and has been specifically optimized for use on Applied Cells’ proprietary MARS® Bar platform.

From Applied Cells 4 Jun 2024

Canagliflozin enhances senescent cell clearance, improving aging-related conditions

Whether sodium-glucose co-transporter 2 (SGLT2) inhibitors induce senolysis.

3 Jun 2024

Stem cell models unlock secrets of early human embryo development

A new study using stem cell-based models has shed new light on how the human embryo begins to develop, which could one day benefit the development of fertility treatment.

31 May 2024

Stem cell breakthrough: EPHA2 protein may hold key to safer regenerative therapies

Pluripotent stem cells (PSCs) are a type of stem cells capable of developing into various cell types. Over the past few decades, scientists have been working towards the development of therapies using PSCs.

30 May 2024

Miniaturized CRISPR protein opens door for gene therapy with adeno-associated virus

Researchers have developed a novel version of a key CRISPR gene-editing protein that shows efficient editing activity and is small enough to be packaged within a non-pathogenic virus that can deliver it to target cells.

30 May 2024

Cervix-on-a-Chip: A breakthrough model for studying women's health

Bacterial Vaginosis (BV) has been identified as one of the many unmet needs in women's health and affects more than 25% of reproductive-aged women.

30 May 2024

Study reveals sex-specific cognitive effects of astrocytic receptors

Weill Cornell Medicine scientists have uncovered the first evidence that astrocyte receptors can trigger opposite effects on cognitive function in male and female preclinical models.

30 May 2024

How tight binding between immune cells dictates T cell cancer-fighting ability

Immunotherapy, treatments that reinvigorate immune cells' anti-cancer activity or reprogram T cells to target cancer, has shown promise in treating leukemias but has not yet been realized in solid tumors.

30 May 2024

Mast cells and PGE2: Key players in controlling asthma inflammation

Previous research indicates that mast cells, a type of immune cell found in the tissues throughout the body, cause inflammation during an asthma attack, inducing symptoms such as trouble breathing and narrowing of the airways.

30 May 2024

Newly discovered lincRNA controls the development and function of regulatory T cells

The T cells in our blood fight against cancer, viruses and bacteria. Specific regulatory T cells are required to control faulty immune responses, and disruption in their function may lead to autoimmune diseases or cancer.

30 May 2024

hnRNPM's protective role in protein synthesis precision uncovered

Researchers at Baylor College of Medicine and collaborating institutions have discovered that a protein called hnRNPM helps protect the integrity of the process cells use to make proteins.

30 May 2024

Researchers develop novel method to 'grow your own' donor skin

Skin grafting is an essential procedure used to treat severe skin wounds. In the case of extensive wounds, however, it can be challenging to harvest enough donor skin, and generating artificial skin substitutes that include hair follicles and sweat glands and can engraft on deep wounds has not been successful.

29 May 2024

New AI model Dev-ResNet accurately monitors embryonic development in real-time

Research led by the University of Plymouth has shown that a new deep learning AI model can identify what happens and when during embryonic development, from video.

28 May 2024

Scientists design new way to "cloak" proteins for targeted therapeutic delivery

Cornell University scientists have designed a way to "cloak" proteins in a generalized technique that could lead to repurposing things like antibodies for biological research and therapeutic applications.

28 May 2024

MUSC researchers unravel the mystery of cancer recurrence

MUSC Hollings Cancer Center researchers have unlocked a discovery that could help to explain why cancer can recur in patients who have undergone chemotherapy or radiotherapy.

28 May 2024

Understanding genetic mosaicism in human cells

In a study led by Jan Korbel at the European Molecular Biology Laboratory (EMBL) and Ashley Sanders at the Berlin Institute for Medical Systems Biology of the Max Delbrück Center (MDC-BIMSB), researchers have found that approximately one in 40 human bone marrow cells carry massive chromosomal alterations – copy number variations and chromosomal rearrangements, for example – without causing any apparent disease or abnormality.

28 May 2024

Cell Biology

Study reveals new insight into how human telomeres function at the molecular level

Understanding the role of tumor-associated fibrosis in immunotherapy resistance

Unraveling the role of follicular helper lymphocytes in antibody production against viruses and allergies

Proteomic profiling reveals sexual dimorphism and immune system alterations in Werner syndrome

Applied Cells releases game-changing reagent kits to empower cell therapy development

Canagliflozin enhances senescent cell clearance, improving aging-related conditions

Stem cell models unlock secrets of early human embryo development

Stem cell breakthrough: EPHA2 protein may hold key to safer regenerative therapies

Miniaturized CRISPR protein opens door for gene therapy with adeno-associated virus

Cervix-on-a-Chip: A breakthrough model for studying women's health

Study reveals sex-specific cognitive effects of astrocytic receptors

How tight binding between immune cells dictates T cell cancer-fighting ability

Mast cells and PGE2: Key players in controlling asthma inflammation

Newly discovered lincRNA controls the development and function of regulatory T cells

hnRNPM's protective role in protein synthesis precision uncovered

Researchers develop novel method to 'grow your own' donor skin

New AI model Dev-ResNet accurately monitors embryonic development in real-time

Scientists design new way to "cloak" proteins for targeted therapeutic delivery

MUSC researchers unravel the mystery of cancer recurrence

Understanding genetic mosaicism in human cells

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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