Cell Biology

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Scientists reveal novel brain network linked to pain in Parkinsonism

Scientists have revealed a novel brain network that links pain in Parkinson's disease (PD) to a specific region of the brain, according to a report in the journal eLife.

28 Aug 2018

Protein modifications that indicate disease

Researchers from the University of Zurich can, for the first time, precisely characterize the protein modification ADP-ribosylation for all proteins in a tissue sample.

28 Aug 2018

Researchers develop 3D map of the human genome

Researchers have developed a way of mapping the positions of genes within cells to understand more about how the genome is organized.

28 Aug 2018

International research effort yields 'Image-Activated Cell Sorting' technology

Invented over 50 years ago, flow cytometry-based cell sorting has become a widely used tool in biology labs for physically isolating cells based on their global surface marker expression profiles.

28 Aug 2018

Research solves mystery on nature of EGFR signaling and how it drives development

What do cancer and the growing legs of a fruit fly have in common? They can both be influenced by a single molecule, a protein that tends to call the shots inside of embryos as they develop into living, breathing animals.

28 Aug 2018

Pancreas' network of enzyme ducts resembles formation of rivers

With methods used to analyze road systems and rivers researchers from the University of Copenhagen have studied the formation of the pancreas' network of ducts transporting digestive enzymes in mice.

27 Aug 2018

Discovery will allow scientists to target hypoxia in cancer

Researchers have discovered a new GPCR that will allow them to target hypoxia in cancer, offering a new, less harmful treatment for patients.

27 Aug 2018

Study sheds light on how cholera became a human pathogen

Scientists think they may have discovered how V. cholerae became a human pathogen, through its ability to interact with amoebae in aquatic environments.

27 Aug 2018

Researchers identify series of molecules involved in regeneration of damaged nerves

Researchers at Nagoya University have identified the series of molecules involved in the regeneration of damaged nerves in roundworm, showing that it largely overlaps with the signals used by the intrinsic removal system to take up and process dying cells.

24 Aug 2018

Scientists identify molecular pit crew responsible for refueling in signaling cells

During IndyCar races, pit stop crews will often refuel a car, replace wheels and complete minor repairs on a race car within 10 seconds. In this short time, a dozen or so people work rapidly and in a highly coordinated manner to complete a number of tasks with extraordinary efficiency.

24 Aug 2018

Study finds how animal guts have evolved to defend themselves from microbial attack

A new Nature Communications paper has journeyed to the inside of our insides, as a team from the Okinawa Institute of Science and Technology Graduate University has mapped the evolutionary journey of how animal guts have evolved to defend themselves from microbial attack.

24 Aug 2018

Researchers stimulate neural recovery in model of traumatic brain injury

Researchers have electrically stimulated neural recovery in a model of traumatic brain injury, providing new treatment insights.

24 Aug 2018

Researchers uncover how RNA regulates genes during critical stage in embryonic brain development

Scientists at the Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago and colleagues discovered how a type of RNA, called Evf2 enhancer RNA, regulates key genes during a critical stage in embryonic brain development.

24 Aug 2018

Finding ways to improve cell replacement therapy for Parkinson's disease

Parkinson's disease is a neurodegenerative disease that affects dopamine signaling neurons in patients' brains. Cell-replacement therapy shows some promise as a treatment for Parkinson's. A recent paper in the journal Molecular & Cellular Proteomics reports a technical advance in selecting cells to use in this therapy.

24 Aug 2018

Study provides new clues to connection between aging and neurodegeneration

For decades researchers have worked to shed light on the causes of neurodegenerative disorders, a group of devastating conditions, including Alzheimer's and Parkinson's, that involve the progressive loss of neurons and nervous system function. In recent years, numerous factors, from genetic mutations to viral infections, have been found to contribute to the development of these diseases.

23 Aug 2018

Scientists demonstrate rapid immune system development in newborn babies

Using new analytical techniques, researchers have shown for the first time the dramatic development of the human immune system after birth.

23 Aug 2018

Location of proteins on bacterial surface can impact pathogenicity of pneumococcal strains

Successful pathogenic strains of pneumococci have two proteins that, owing to their location on the surface of the bacteria, enhance their survival and ability to cause disease, a study from Karolinska Institutet in Sweden published in Nature Communications, reports.

23 Aug 2018

Researchers describe how RNA polymerase detects UV light damage in DNA

Damage to DNA is a constant threat to cellular life, and so it is constantly monitored and detected by a family of enzymes called RNA polymerases, resulting in subsequent repair to maintain genome integrity.

23 Aug 2018

Researchers develop faster method to grow brain cells from stem cells

Researchers at Lund University in Sweden have developed a faster method to generate functional brain cells, called astrocytes, from embryonic stem cells. Astrocytes play a significant role in neurodegenerative diseases.

22 Aug 2018

Researchers engineer peptide nanoparticles to outsmart biological system and target kidney cells

Remember the scene in the movie Mission: Impossible when Tom Cruise has to sneak into the vault? He had to do all sorts of moves to avoid detection. That's what it's like to sneak a targeted drug into a kidney and keep it from getting eliminated from the body.

22 Aug 2018

Cell Biology

Scientists reveal novel brain network linked to pain in Parkinsonism

Protein modifications that indicate disease

Researchers develop 3D map of the human genome

International research effort yields 'Image-Activated Cell Sorting' technology

Research solves mystery on nature of EGFR signaling and how it drives development

Pancreas' network of enzyme ducts resembles formation of rivers

Discovery will allow scientists to target hypoxia in cancer

Study sheds light on how cholera became a human pathogen

Researchers identify series of molecules involved in regeneration of damaged nerves

Scientists identify molecular pit crew responsible for refueling in signaling cells

Study finds how animal guts have evolved to defend themselves from microbial attack

Researchers stimulate neural recovery in model of traumatic brain injury

Researchers uncover how RNA regulates genes during critical stage in embryonic brain development

Finding ways to improve cell replacement therapy for Parkinson's disease

Study provides new clues to connection between aging and neurodegeneration

Scientists demonstrate rapid immune system development in newborn babies

Location of proteins on bacterial surface can impact pathogenicity of pneumococcal strains

Researchers describe how RNA polymerase detects UV light damage in DNA

Researchers develop faster method to grow brain cells from stem cells

Researchers engineer peptide nanoparticles to outsmart biological system and target kidney cells

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