Cell Biology

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BioCina and NovaCina forge strategic alliance to offer biologics developers integrated drug substance and drug product solutions

BioCina Pty Ltd., a global end-to-end biologics Contract Development and Manufacturing Organisation (CDMO), and NovaCina Pty Ltd., a global fill-and-finish CDMO, announced a strategic partnership to provide integrated drug substance and drug product solutions for biologics developers.

From BioCina Pty Ltd. 29 Feb 2024

New tool can streamline the analysis of complex epigenome and epitranscriptome data

Scientists have extensively researched the structure and sequence of genetic material and its interactions with proteins in the hope of understanding how our genetics and environment interact in diseases.

28 Feb 2024

EPFL scientists uncover protein degradation mechanism preventing autoimmune reactions

Scientists at EPFL uncover the mechanism by which cells mark the protein cGAS for degradation, which is critical in preventing the immune system from mistakenly attacking the body's own tissues.

28 Feb 2024

Neuroscientists uncover surprising role of glia in regulating neuronal responses in the brain

Neuroscientists at Fred Hutchinson Cancer Center have found that an often-overlooked type of brain cell called glia has more of a role in brain function than previously thought.

28 Feb 2024

Novel "Tissue-in-a-CUBE" model mimics blood-brain barrier for drug testing

A research team at the RIKEN Center for Biosystems Dynamics Research (BDR) in Japan has succeeded in establishing a model of the blood-brain barrier using modularized tissue derived from human cells.

28 Feb 2024

Novel brain organoid model unveils link between inflammation and astrocyte dysfunction

The brain is typically depicted as a complex web of neurons sending and receiving messages. But neurons only make up half of the human brain.

28 Feb 2024

Revolutionary stem cell culture method produces full model of human central nervous system

The first stem cell culture method that produces a full model of the early stages of the human central nervous system has been developed by a team of engineers and biologists at the University of Michigan, the Weizmann Institute of Science, and the University of Pennsylvania.

26 Feb 2024

Study sheds light on the composition of nuclear matrix in Arabidopsis thaliana

Chromatin is a unique DNA and protein complex that makes up the chromosomes. Specific proteins (histones) wind up the DNA like small cable drums to package the long DNA.

23 Feb 2024

Decoding how bats distinguish sounds for navigation and communication

Seba's short-tailed bat (Carollia perspicillata) lives in the subtropical and tropical forests of Central and South America, where it mostly feeds on pepper fruit.

23 Feb 2024

AI tool helps develop the most complete map of the bacterial essential interactome

Universitat Autonoma de Barcelona (UAB) researchers have produced the most complete map of the bacterial essential interactome, i.e. how proteins combine and interact to perform functions essential for their survival.

23 Feb 2024

Research reveals bacteria's dynamic defense duo against phage viruses

Scientists at the University of Southampton have discovered that bacteria can pair up their defense systems to create a formidable force, greater than the sum of its parts, to fight off attack from phage viruses.

23 Feb 2024

Understanding how stress accelerates cancer spread

Stress is inevitable. But too much of it can be terrible for our health. Chronic stress can increase our risk for heart disease and strokes.

22 Feb 2024

Study reveals unexpected link between cell membrane damage and cellular senescence

Our cells are surrounded by a fragile membrane that's only 5 nanometers thick, 1/20 of a soap bubble. Cells are easily damaged by physiological activities, including muscle contraction and tissue injury.

22 Feb 2024

Neural cell culture model sheds light on the intricate mechanisms underlying neurodegeneration

Scientists at the University of Zurich have developed an innovative neural cell culture model, shedding light on the intricate mechanisms underlying neurodegeneration.

22 Feb 2024

Link between gut microbiome and premature aging unveiled in chronic HIV patients

The Wistar Institute's associate professor Mohamed Abdel-Mohsen, Ph.D., has demonstrated, with his lab and collaborators, a connection between viral damage to the gut and premature biological aging.

22 Feb 2024

Intramolecular bivalent glues: A promising avenue for protein degradation

Living cells resemble highly organized small towns - in addition to energy production, transportation systems, and construction, cells also require efficient waste disposal.

21 Feb 2024

“Laboratory testicles” could solve male infertility mysteries

The testis is responsible for sperm production and testosterone synthesis. Abnormalities in testis development and function lead to disorders of sex development (DSD) and male infertility. Currently, no in vitro system exists for modeling the testis.

20 Feb 2024

Study reveals novel mechanism for longevity of oocytes

Oocytes are immature egg cells that develop in almost all female mammals before birth. The propagation of future generations depends on this finite reserve of cells surviving for many years without incurring damage.

20 Feb 2024

Breakthrough gene therapy method utilizes bird retrotransposon for safe gene insertion

The recent approval of a CRISPR-Cas9 therapy for sickle cell disease demonstrates that gene editing tools can do a superb job knocking out genes to cure hereditary disease.

20 Feb 2024

Researchers develop artificial cell environment to promote nerve regeneration

Injuries in the central nervous system heal poorly because cavities scar. Researchers hope to remedy this problem by filling the cavities in such a way that stem cells feel comfortable in them.

20 Feb 2024

Cell Biology

BioCina and NovaCina forge strategic alliance to offer biologics developers integrated drug substance and drug product solutions

New tool can streamline the analysis of complex epigenome and epitranscriptome data

EPFL scientists uncover protein degradation mechanism preventing autoimmune reactions

Neuroscientists uncover surprising role of glia in regulating neuronal responses in the brain

Novel "Tissue-in-a-CUBE" model mimics blood-brain barrier for drug testing

Novel brain organoid model unveils link between inflammation and astrocyte dysfunction

Revolutionary stem cell culture method produces full model of human central nervous system

Study sheds light on the composition of nuclear matrix in Arabidopsis thaliana

Decoding how bats distinguish sounds for navigation and communication

AI tool helps develop the most complete map of the bacterial essential interactome

Research reveals bacteria's dynamic defense duo against phage viruses

Understanding how stress accelerates cancer spread

Study reveals unexpected link between cell membrane damage and cellular senescence

Neural cell culture model sheds light on the intricate mechanisms underlying neurodegeneration

Link between gut microbiome and premature aging unveiled in chronic HIV patients

Intramolecular bivalent glues: A promising avenue for protein degradation

“Laboratory testicles” could solve male infertility mysteries

Study reveals novel mechanism for longevity of oocytes

Breakthrough gene therapy method utilizes bird retrotransposon for safe gene insertion

Researchers develop artificial cell environment to promote nerve regeneration

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