Cell Biology

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Retooling the cell's polypeptide manufacturing plants to generate polymer chains

Synthetic biologists have become increasingly creative in engineering yeast or bacteria to churn out useful chemicals - from fuels to fabrics and drugs - beyond the normal repertoire of microbes.

13 Jun 2023

Regulatory connection between DREAM and cellular senescence may play a potential role in aging process

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 10, entitled, "Key elements of cellular senescence involve transcriptional repression of mitotic and DNA repair genes through the p53-p16/RB-E2F-DREAM complex."

13 Jun 2023

New process for creating a “meta-cell overcomes the challenges of studying single-cell secrets

University of California, Irvine neuroscientists probing the gene changes behind Alzheimer's disease have developed a process of making a "meta-cell" that overcomes the challenges of studying a single cell.

13 Jun 2023

Study shows link between death perception and reduced aging in flies

Researchers led by Christi Gendron at the University of Michigan, US, have found the link between death perception and reduced aging in flies.

13 Jun 2023

DYRK1A gene may dictate susceptibility to multiple highly pathogenic coronaviruses

Entry of the SARS-CoV-2 virus into human tissues depends on the activity of a host gene that regulates production of a key viral receptor, according to a study publishing June 13th in the open access journal PLOS Biology by Madison Strine and Craig Wilen of Yale University, US, and colleagues.

13 Jun 2023

Using heart and lung stem cells to better understand how COVID-19 impacts different organs

Researchers have used heart and lung stem cells infected with the virus that causes COVID-19 to better understand how the disease impacts different organs, paving the way for more targeted treatments.

13 Jun 2023

Maximizing the function and potential of stem cell-based treatments for patients with Type 1 diabetes

Following encouraging results from pre-clinical research and a recent clinical trial on stem cell-based treatments for patients with Type 1 diabetes, researchers are now working on maximizing the function and potential of stem cell-based treatments for future application in patients.

13 Jun 2023

Study illuminates how T cells fight and remember infections

The immune system protects the body from invaders, such as bacteria, viruses, or tumors, with its intricate network of proteins, cells, and organs.

13 Jun 2023

Scientists uncover the structure of the first step in amyloid formation for Huntington's disease

Devastating neurodegenerative diseases like Huntington's, Alzheimer's, and Parkinson's are all associated with protein deposits in the brain, known as amyloid.

13 Jun 2023

Study reveals biologically validated imaging-based evidence of medically induced myelin repair

A decade after UC San Francisco scientists identified an over-the-counter antihistamine as a treatment for multiple sclerosis, researchers have developed an approach to measure the drug's effectiveness in repairing the brain, making it possible to also assess future therapies for the devastating disorder.

13 Jun 2023

Manipulating white blood cells to eliminate solid tumors

By silencing the molecular pathway that prevents macrophages from attacking our own cells, Penn Engineers have manipulated these white blood cells to eliminate solid tumors.

12 Jun 2023

New cell culture model generates the alveolar macrophage in the lab

Researchers at Texas Biomedical Research Institute have succeeded in generating the lung's most important immune cell, the alveolar macrophage, in the lab.

12 Jun 2023

Researchers create a new method of studying nano-sized particles

Researchers at Karolinska Institutet have created a new method of studying the smallest bioparticles in the body.

12 Jun 2023

Study raises new hopes for blood cancer patients with an incomplete response to CAR T cell therapy

The aim of immunotherapy strategies is to use cells in the patient's own immune system to destroy tumor cells. CAR T cell therapy is an immunotherapy that is effective in treating blood cancer.

12 Jun 2023

Researchers discover how a sugar molecule can affect cancer cell response to chemoradiotherapy

Researchers at Georgetown University's Lombardi Comprehensive Cancer Center and colleagues who have been exploring the complexities of biochemical pathways involved in cancer development have found that a form of glucose, a type of sugar, is intricately linked to a pathway used to build DNA molecules.

12 Jun 2023

Study reveals how p62 bodies control redox-independent stress response

Cellular stress, or oxidative stress, occurs when there is a buildup of reactive oxygen species (ROS), which interferes with cellular mechanisms and can even cause damage to proteins, lipids, and DNA.

12 Jun 2023

Vaccine against deadly chytrid fungus shifts microbiome to make frogs more resilient to future exposure

A human or animal's microbiome - the collection of often beneficial microorganisms, including as bacteria and fungi, that live on or within a host organism - can play an important role in the host's overall immune response, but it is unclear how vaccines against harmful pathogens impact the microbiome.

11 Jun 2023

Researchers identify microRNAs associated with a weakened immune response to COVID-19

A team of researchers at NYU Abu Dhabi, led by Associate Professor of Biology Youssef Idaghdour and working in collaboration with clinicians at several Abu Dhabi hospitals, investigated the association between microRNAs, a class of small RNA molecules that regulate genes, and COVID-19 severity among 259 unvaccinated COVID-19 patients living in Abu Dhabi.

11 Jun 2023

Researchers create first integrated single-cell atlas of the human lung

The largest and most comprehensive cell map of the human lung is announced in Nature Medicine today (8 June). Revealing the great diversity of cell types in the lung and key differences between health and disease, the Human Lung Cell Atlas will be a valuable resource for lung researchers.

10 Jun 2023

Scientists determine the atomic-level structure of a zinc-transporter protein

Scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory have determined the atomic-level structure of a zinc-transporter protein, a molecular machine that regulates levels of this crucial trace metal micronutrient inside cells.

9 Jun 2023

Cell Biology

Retooling the cell's polypeptide manufacturing plants to generate polymer chains

Regulatory connection between DREAM and cellular senescence may play a potential role in aging process

New process for creating a “meta-cell overcomes the challenges of studying single-cell secrets

Study shows link between death perception and reduced aging in flies

DYRK1A gene may dictate susceptibility to multiple highly pathogenic coronaviruses

Using heart and lung stem cells to better understand how COVID-19 impacts different organs

Maximizing the function and potential of stem cell-based treatments for patients with Type 1 diabetes

Study illuminates how T cells fight and remember infections

Scientists uncover the structure of the first step in amyloid formation for Huntington's disease

Study reveals biologically validated imaging-based evidence of medically induced myelin repair

Manipulating white blood cells to eliminate solid tumors

New cell culture model generates the alveolar macrophage in the lab

Researchers create a new method of studying nano-sized particles

Study raises new hopes for blood cancer patients with an incomplete response to CAR T cell therapy

Researchers discover how a sugar molecule can affect cancer cell response to chemoradiotherapy

Study reveals how p62 bodies control redox-independent stress response

Vaccine against deadly chytrid fungus shifts microbiome to make frogs more resilient to future exposure

Researchers identify microRNAs associated with a weakened immune response to COVID-19

Researchers create first integrated single-cell atlas of the human lung

Scientists determine the atomic-level structure of a zinc-transporter protein

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