Cell Biology

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Study reveals key signaling pathways driving lung cancer metastasis

When it comes to cancer metastasis, it takes two to tango. That was one of the key findings of a new study led by researchers at Memorial Sloan Kettering Cancer Center (MSK): The TGF-beta and RAS signaling pathways work together to spur the spread of cancer in lung adenocarcinoma, a leading cause of cancer deaths around the world.

6 Sep 2024

Study reveals key cell structure for heat perception in humans

A study by the Medical University of Vienna has made important progress in understanding heat perception in humans.

5 Sep 2024

Breakthrough research identifies key microenvironments linked to kidney injury and disease

A study published in Nature Communications provides new insight into how damaged cells interact within disease-promoting microenvironments following acute kidney injury, or AKI.

5 Sep 2024

New technique promises faster DNA analysis in sexual assault cases

A team of researchers has developed a radical new technique for analyzing evidence in sexual assault cases. The new approach could streamline the forensics pipeline and reduce delays in the processing of DNA evidence.

5 Sep 2024

A call for robust H5N1 influenza preparedness and response

As the global threat of H5N1 influenza looms with outbreaks across species and continents including the U.S., three international vaccine and public health experts say it is time to fully resource and support a robust strategy to address this and future potential pandemic influenza threats, including to consider voluntary vaccination for those now at exposure risk.

5 Sep 2024

A new genetic perspective on monilethrix

From infancy and usually for life, some families suffer from broken hair due to a congenital form of hair loss called monilethrix. Researchers at the University Hospital Bonn and the University of Bonn have now identified causative mutations in another keratin gene, KRT31. They hope that this will improve the diagnosis of this rare disease. Their results have now been published in the renowned "British Journal of Dermatology".

5 Sep 2024

Study reveals menstrual cycle’s role in spreading mutant cells in breast tissue

A team of researchers at the VIB-KU Leuven Center for Cancer Biology, the Netherlands Cancer Institute and Oncode Institute and the University of Cambridge have discovered that a defensive mechanism connected to the menstrual cycle plays a role in spreading mutant cells within mammary tissue.

4 Sep 2024

Astrocytes reprogrammed to brain stem cells through methylation

Resting brain stem cells hardly differ from normal astrocytes, which support the nerve cells in the brain.

4 Sep 2024

Allen Institute and NYSCF launch collaboration to create inclusive cellular models

Today, the Allen Institute for Cell Science and New York Stem Cell Foundation (NYSCF) announced a pioneering collaboration to address this critical issue, combining two cutting-edge technologies to create more inclusive cellular models for studying disease.

4 Sep 2024

A novel therapeutic option for HER2-positive extramammary Paget disease

The research article presents a comprehensive evaluation of the human epidermal growth factor receptor 2 (HER2) status in extramammary Paget disease (EMPD) and explores the therapeutic potential of disitamab vedotin (DV), a novel humanized anti-HER2 antibody-drug conjugate (ADC), for this rare adenocarcinoma.

4 Sep 2024

Study shows beta cells can function independently for glycemic control

Our glycemic balance is based on the ability of the pancreatic beta cells to detect glucose and secrete insulin to maintain our blood sugar levels. If these cells malfunction, the balance is broken, and diabetes develops.

3 Sep 2024

Extraordinary cell division mechanism discovered in common dental plaque bacteria

One of the most diverse ecosystems on the planet is closer than you think -; right inside your mouth. Your mouth is a thriving ecosystem of more than 500 different species of bacteria living in distinct, structured communities called biofilms.

2 Sep 2024

Alternative splicing may influence gene expression more than protein diversity

Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA).

2 Sep 2024

Breakthrough in blood stem cell development offers hope for leukemia and bone marrow failure

Melbourne researchers have made a world first breakthrough into creating blood stem cells that closely resemble those in the human body. And the discovery could soon lead to personalized treatments for children with leukemia and bone marrow failure disorders.

2 Sep 2024

NCCS study uses exosomes to overcome resistance to epidermal growth factor receptor inhibitors

In a new study, clinician-scientists and researchers from the National Cancer Centre Singapore (NCCS) have demonstrated the use of exosomes to successfully target squamous cell cancer tumours that are usually resistant to epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs). Their research is the first where exosomes have been applied to target TKI-resistant cancers in Singapore. The findings were published in the journal Developmental Cell last month.

2 Sep 2024

Autophagy in HPCs modulates exosomal miRNAs to inhibit liver fibrosis

The study investigates the role of autophagy in hepatic progenitor cells (HPCs) and its potential to modulate exosomal microRNAs (miRNAs) to inhibit liver fibrosis in the context of schistosomiasis, a disease caused by parasitic flatworms that can lead to severe organ damage, particularly to the liver.

2 Sep 2024

Mosquito males’ visual and auditory cues reveal new insights for malaria control

A high-pitched buzzing sound in your ear is an unmistakable sign that a female mosquito is out on the hunt -; for they, not males, drink blood. Hearing that tone might make you turn to try to swat the pest. But for a male mosquito, that tone means it's time to mate.

30 Aug 2024

EU-funded MASTER project develops first comprehensive database of food metagenomes

The first comprehensive database of food metagenomes has been developed by the EU-funded MASTER project.

30 Aug 2024

AI tool RENAISSANCE transforms creation of kinetic models in cellular metabolism

Understanding how cells process nutrients and produce energy - collectively known as metabolism - is essential in biology. However, analyzing the vast amounts of data on cellular processes to determine metabolic states is a complex task.

30 Aug 2024

Ingenza announces partnership with Cellugy to investigate the potential of biofabricated cellulose

Industrial biotech specialist Ingenza is delighted to announce that it is collaborating with Cellugy to accelerate the development of its innovative platform for producing biofabricated cellulose. This technology will provide a sustainable alternative to fossil-based petrochemicals in various industrial applications, starting with personal care. The new project will ultimately accelerate the understanding and optimization of bacterial cellulose production.

From Ingenza Ltd 30 Aug 2024

Cell Biology

Study reveals key signaling pathways driving lung cancer metastasis

Study reveals key cell structure for heat perception in humans

Breakthrough research identifies key microenvironments linked to kidney injury and disease

New technique promises faster DNA analysis in sexual assault cases

A call for robust H5N1 influenza preparedness and response

A new genetic perspective on monilethrix

Study reveals menstrual cycle’s role in spreading mutant cells in breast tissue

Astrocytes reprogrammed to brain stem cells through methylation

Allen Institute and NYSCF launch collaboration to create inclusive cellular models

A novel therapeutic option for HER2-positive extramammary Paget disease

Study shows beta cells can function independently for glycemic control

Extraordinary cell division mechanism discovered in common dental plaque bacteria

Alternative splicing may influence gene expression more than protein diversity

Breakthrough in blood stem cell development offers hope for leukemia and bone marrow failure

NCCS study uses exosomes to overcome resistance to epidermal growth factor receptor inhibitors

Autophagy in HPCs modulates exosomal miRNAs to inhibit liver fibrosis

Mosquito males’ visual and auditory cues reveal new insights for malaria control

EU-funded MASTER project develops first comprehensive database of food metagenomes

AI tool RENAISSANCE transforms creation of kinetic models in cellular metabolism

Ingenza announces partnership with Cellugy to investigate the potential of biofabricated cellulose

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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