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Groundbreaking malaria vaccine provides high-level protection with just one dose

Scientists at Sanaria and Seattle Children's Research Institute's Center for Global Infectious Disease Research (CGIDR) have unveiled a groundbreaking malaria vaccine, Sanaria® PfSPZ-LARC2 Vaccine, designed to provide high-level protection with just one dose.

12 Feb 2025

US funding suspension threatens health and research programs in Uganda

Malaria vaccination and HIV treatment are among numerous health programmes at risk in Uganda as the country's science research centres suffer the impact of a US freeze on overseas aid.

12 Feb 2025

Inhaled antibody therapy shows promise for COVID-19 treatment

The inhaled monoclonal antibody IN-006 shows promise in COVID-19 treatment, with high airway antibody levels and a favorable safety profile in healthy adults.

12 Feb 2025

New immune map uncovers key pancreatic cancer insights

Researchers determine a complex immune infiltrate pattern based on a newly constructed immune map developed using pancreatic cancer cells.

12 Feb 2025

Harvard Pilgrim Health Care Institute launches new center for sepsis research

The Harvard Pilgrim Health Care Institute is proud to announce the launch of the Center for Sepsis Epidemiology and Prevention Studies (SEPSIS).

11 Feb 2025

PAHO issues alert on rising risk of dengue outbreaks in the Americas

The Pan American Health Organization (PAHO) has issued an epidemiological alert regarding the increased risk of dengue outbreaks in the Americas, attributed to the growing circulation of the DENV-3 serotype in several countries in the region.

11 Feb 2025

Gut microbes influence how well cancer patients respond to immunotherapy

Researchers discovered that gut microbiota-derived hexa-acylated LPS enhances the effectiveness of anti-PD-1 cancer immunotherapy, while penta-acylated LPS may suppress immune responses.

11 Feb 2025

Diabetes medications may help lower COPD flare-up risk, study finds

The study reveals SGLT-2is are linked to fewer COPD exacerbations in type 2 diabetes, suggesting a need for further clinical trials to confirm these findings.

11 Feb 2025

Targeted polymersomes boost methotrexate efficacy for aggressive choriocarcinoma treatment

Researchers develop targeted polymersomes loaded with methotrexate for the treatment of gestational choriocarcinoma,

11 Feb 2025

Severe infections linked to increased risk of heart failure

Findings highlight the importance of infection prevention measures and personalized heart failure care.

11 Feb 2025

NIH clinical trial examines investigational therapy for dengue

A clinical trial supported by the National Institutes of Health (NIH) is testing an experimental treatment designed to help people suffering the effects of dengue, a mosquito-borne viral disease.

11 Feb 2025

Single dose of antibody shields macaques from severe H5N1 influenza

National Institutes of Health (NIH) scientists and their colleagues report that a single dose of a broadly neutralizing antibody (bnAb) administered prior to virus exposure protects macaques from severe H5N1 avian influenza.

11 Feb 2025

Adrenomedullin hormone as key driver of insulin resistance in obesity-linked type 2 diabetes

Researchers investigate the underlying mechanisms of endothelial insulin resistance involved in obesity-associated diabetes.

11 Feb 2025

Colorado study tracks long COVID healthcare utilization

A new study analyzing Long COVID healthcare utilization in Colorado reveals a significant shift from acute care to outpatient services following diagnosis, shedding light on evolving treatment patterns and the broader healthcare burden posed by the condition.

11 Feb 2025

AI approach reveals possible fusion of rare diseases in COVID-19 origins

Despite extensive research, the origins of COVID-19 remain elusive. In a new study published in the KeAi journal Advances in Biomarker Sciences and Technology (ABST), an AI-driven approach was adopted to examine DNA methylation patterns at 865,859 CpG sites in blood samples from early COVID-19 patients.

10 Feb 2025

Groundbreaking advances in tuberculosis vaccine development and therapies

Despite decades of efforts, tuberculosis remains a global health crisis, claiming over 1.3 million lives annually.

10 Feb 2025

Influenza A virus changes shape to evade immune responses

Influenza A virus particles strategically adapt their shape-to become either spheres or larger filaments-to favor their ability to infect cells depending on environmental conditions, according to a new study from National Institutes of Health (NIH) scientists.

10 Feb 2025

Tick-borne encephalitis emerges in Britain: Experts urge vigilance

Tick-borne encephalitis virus (TBEV) has now been confirmed in locally acquired human cases in the U.K., with evidence of established transmission in British tick populations. Increased surveillance and clinician awareness are crucial to detecting and managing this emerging threat.

10 Feb 2025

Study highlights growing antibiotic resistance in diarrheagenic E. coli in China

Diarrheagenic E. coli (DEC) is a major global cause of diarrheal diseases, with certain strains showing alarming levels of antibiotic resistance.

10 Feb 2025

House cats with bird flu could pose a risk to public health

More than 80 domestic cats, among many other types of mammals, have been confirmed to have had bird flu since 2022 — generally barn cats that lived on dairy farms, as well as feral cats and pets that spend time outdoors and likely caught it by hunting diseased rodents or wild birds.

10 Feb 2025