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Study highlights the role of genetic factors in COVID-19 thrombosis and inflammation

Despite global vaccination efforts, COVID-19 continues to pose significant risks, leading to severe complications and fatalities. These risks are driven by disrupted coagulation, impaired fibrinolysis, which is the process of breaking blood clots, and heightened inflammatory responses.

3 Oct 2024

New insights into the link between respiratory infections and chronic lung diseases

A 3D reconstruction of a mouse lung four days after infection with fluorescent Sendai virus reveals widespread virus presence (red) and active replication (green).

3 Oct 2024

Scientists identify gut microbial signatures that distinguish diseases and predict health states

Study reveals significant gut microbial differences across diseases in the Chinese population, identifying universal microbial signatures that could predict disease states with high accuracy.

2 Oct 2024

Long-lived plasma cells fail to establish after COVID mRNA vaccination, limiting long-term antibody response

Researchers found that SARS-CoV-2-specific plasma cells were largely excluded from the long-lived plasma cell compartment in the bone marrow after mRNA vaccination, explaining the short-lived antibody response.

2 Oct 2024

Long COVID affects 38% of emergency patients with persistent symptoms

Researchers found that post-COVID-19 condition (PCC) symptoms persist in a significant number of both SARS-CoV-2 positive and negative emergency department patients, highlighting the non-specific nature of the WHO’s PCC criteria.

1 Oct 2024

Study reveals genetic elements driving Klebsiella pneumoniae hypervirulence

More than a decade ago, physicians around the world began reporting cases due to a new hypervirulent strain of Klebsiella pneumoniae, which could infect and severely sicken otherwise healthy people.

1 Oct 2024

Emergency response underway as Rwanda battles deadly Marburg virus

The World Health Organization (WHO) is readying emergency supplies to send to Rwanda following the country's first outbreak of the highly contagious Marburg virus, as authorities attempt to trace people who may be at risk.

1 Oct 2024

New humanized mouse models created to study COVID-19

Scientists at La Jolla Institute for Immunology (LJI) have developed six lines of humanized mice that can serve as valuable models for studying human cases of COVID-19.

1 Oct 2024

Study reveals widespread long-COVID symptoms, challenging WHO definition

Study reveals that more than one-third of SARS-CoV-2 positive patients experience long-COVID symptoms three months after an emergency department visit, with significant overlap in symptoms observed among negative patients.

1 Oct 2024

Brazil achieves milestone in eliminating lymphatic filariasis

The World Health Organization (WHO) congratulates Brazil for having eliminated lymphatic filariasis as a public health problem.

1 Oct 2024

Uncovering the secrets of malaria parasite cell division

A team of scientists at the University of Nottingham, have uncovered how the parasite that causes malaria orchestrates their cell division – which is key in enabling the parasite to transmit this deadly disease.

1 Oct 2024

New mechanism uncovered behind immune decline after tuberculosis treatment

Researchers at Baylor College of Medicine and collaborating institutions have discovered a mechanism that drives the long-term decline in immune response that is observed after tuberculosis (TB) has been successfully treated.

1 Oct 2024

Researchers uncover new disease-linked microbial species through pan-body microbiome analysis

Researchers in Germany conducted a pan-body microbiome analysis, uncovering new microbial species and potential therapies linked to diseases, with implications for diagnostic and therapeutic advancements.

1 Oct 2024

New collaboration aims to break through LGMD treatment barriers

Critical Path Institute (C-Path) today announced the formation of a new task force under its Rare Disease Cures Accelerator-Data and Analytics Platform (RDCA-DAP®), dedicated to advancing therapeutic development for limb-girdle muscular dystrophies (LGMDs).

1 Oct 2024

Scientists uncover role of Wnt in kidney formation

A group of essential signaling molecules known as the Wnt pathway emerged early in the evolution of multicellular life. Scientists have been studying Wnt actions for four decades to comprehend its complex roles in development and disease.

1 Oct 2024

High magnesium levels drive higher mortality in sepsis patients

Study identifies high serum magnesium levels as a significant factor associated with increased mortality in sepsis patients, demonstrating a dose-response relationship across diverse patient cohorts. It highlights magnesium as a potential marker for risk stratification in sepsis.

30 Sep 2024

Macrophage memory following COVID infection provides cross-virus protection

More than 200 viruses can infect and cause disease in humans; most of us will be infected by several over the course of a lifetime.

30 Sep 2024

Discovery of antibodies that boost complement activation against K. pneumoniae

Researchers investigate antibody-dependent complement activation during Klebsiella pneumoniae infection.

30 Sep 2024

Study links COVID-19 to increased risk of acute kidney disorders

Researchers from West China Hospital, Sichuan University, have conducted a study revealing a significant association between COVID-19 and acute kidney disorders (AKD), including acute kidney injury (AKI), that varies over time.

30 Sep 2024

How viral persistence and immune dysfunction drive long COVID

Study explores the biological drivers and mechanisms of long COVID, shedding light on its epidemiology and potential therapeutic interventions. It emphasizes the role of viral persistence, immune dysfunction, and coagulation in the development of this condition.

29 Sep 2024