Disease/Infection News

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Polyphor, Roche agree to develop and commercialize antibiotic for bacterial infections

Polyphor Ltd, a privately held pharmaceutical company, and Roche announced today that they have entered into an exclusive worldwide license agreement to develop and commercialize Polyphor's investigational macrocycle antibiotic, POL7080, for patients suffering from bacterial infections caused by Pseudomonas aeruginosa.

4 Nov 2013

Study: Single dose of HPV vaccine may be sufficient to protect cervical cancer

Women vaccinated with one dose of a human papillomavirus (HPV) vaccine had antibodies against the viruses that remained stable in their blood for four years, suggesting that a single dose of vaccine may be sufficient to generate long-term immune responses and protection against new HPV infections, and ultimately cervical cancer, according to a study published in Cancer Prevention Research, a journal of the American Association for Cancer Research.

4 Nov 2013

Study: Sugar intake is not directly associated with nonalcoholic fatty liver disease

Despite current beliefs, sugar intake is not directly associated with nonalcoholic fatty liver disease, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association. Rather, high-calorie diets promote the progression of this serious form of liver disease.

4 Nov 2013

VG Life Sciences' peptide awarded US patent for HIV treatment

The United States Patent and Trademark Office has issued on October 15, 2013 Patent No.: US 8,557,764 covering the VG Life Sciences' peptide VG1177 for treating HIV infection.

31 Oct 2013

Listeria's resistance to disinfectants

Recent years have seen significant outbreaks of listeriosis on both sides of the Atlantic. Although the disease can usually be treated successfully, it is occasionally fatal, most frequently in pregnant women or immunocompromized people.

31 Oct 2013

EcoHealth Alliance discovers new SARS-like coronavirus in Chinese horseshoe bats

EcoHealth Alliance, a nonprofit organization that focuses on local conservation and global health issues, announced the discovery of a new SARS-like coronavirus (CoV) in Chinese horseshoe bats.

31 Oct 2013

GHIT Fund to host panel discussion to examine recent successes, setbacks in global health

The Global Health Innovative Technology Fund, along with the New York Academy of Sciences and Japan Society, will host a panel discussion - comprised of preeminent global health experts - to examine recent successes and setbacks in global health and what they see as the secret ingredient to moving a vaccine, cure or diagnostic across the finish line and into the field.

31 Oct 2013

HIV infection, not antiretroviral therapy associated with risk for atherosclerosis

HIV infection, not antiretroviral therapy (ART), is associated with risk for atherosclerosis in patients with no history of smoking, particularly those infected for eight years or more.

31 Oct 2013

Researchers find more accurate method to screen for meningococcal infection

Researchers from the University of Missouri School of Medicine have found a more accurate method to screen for bacterial meningococcal infection in its early stages, when it's hardest to detect. According to the researchers, the method for diagnosis could save lives by getting patients treatment earlier, when the infection is most treatable.

31 Oct 2013

Meclizine drug has the potential to treat certain infectious diseases and cancer

Meclizine, an over-the-counter drug used for decades to treat nausea and motion sickness, has the potential for new uses to treat certain infectious diseases and some forms of cancer, according to Dr. Vishal M. Gohil, Texas A&M AgriLife Research biochemist.

31 Oct 2013

CytoDyn submits protocol to FDA for Phase IIb clinical trial of PRO 140

CytoDyn Inc. ("CytoDyn") (OTCQB:CYDY), a biotechnology company focused on the development of new therapies for combating infection with immune deficiency viruses, today announced that CytoDyn Chief Medical Officer David Feigal, M.D., has submitted a revised protocol to the U.S. Food and Drug Administration relating to an upcoming Phase IIb clinical trial of PRO 140, CytoDyn's leading product under development as a treatment for Human Immunodeficiency Virus (HIV) infection.

31 Oct 2013

Canadian researchers contribute to the science of verotoxigenic E. coli and associated infections

Many Canadian scientists and clinicians were unsung heroes during the early years (1977-1983) of research unfolding around verotoxigenic E. coli (VTEC).

30 Oct 2013

Malaria elimination and insecticide resistance: an interview with Professor Hilary Ranson, Liverpool School of Tropical Medicine

The first malaria elimination programme was in the 1950s and 1960s. Malaria was eliminated from many countries in Asia and the Americas, largely by indoor spraying with insecticide. But the campaign had very little impact in Africa and eventually resources were moved away from malaria control.

30 Oct 2013

MRSA cases continue to decline in VA medical centers

Five years after implementing a national initiative to reduce methicillin-resistant Staphylococcus aureus (MRSA) rates in Veterans Affairs (VA) medical centers, MRSA cases have continued to decline, according to a study in the November issue of the American Journal of Infection Control, the official publication of the Association for Professionals in Infection Control and Epidemiology (APIC).

30 Oct 2013

Identifying gaps in infection prevention practices may help improve patient safety, shows study

Identifying gaps in infection prevention practices may yield opportunities for improved patient safety, according to a survey published in the November issue of the American Journal of Infection Control, the official publication of the Association for Professionals in Infection Control and Epidemiology (APIC).

30 Oct 2013

Mice exploit IRG proteins to create resistance mechanism against toxoplasma infection

One of the commonest parasites in the world is Toxoplasma gondii. Toxoplasma can infect most warm-blooded animals, including humans, and causes significant damage to the unborn child if a woman becomes infected for the first time during pregnancy.

30 Oct 2013

Researchers develop new substance that quickly and effectively kills multi-resistant bacteria

In Europe alone, more than 25,000 people die each year from infections caused by multi-resistant bacteria. Researchers from University of Copenhagen have now developed and characterized a substance that quickly and effectively kills the virulent bacteria. The substance employs a multifunctional mechanism that reduces the risk of antibiotic resistance. The findings have recently been published in the scientific journal Chemistry & Biology.

30 Oct 2013

Study looks at the feasibility of Xpert test for TB in real-life clinical setting in southern Africa

The first randomised trial to measure the impact of the rapid Xpert MTB/RIF test for tuberculosis in a real-life clinical setting finds that it can be accurately performed by a non-specialist with minimal training, improves same-day diagnosis and time to starting treatment, and increases the number of people who start treatment after testing positive on day 1 by 50%, compared with conventional TB diagnostics.

30 Oct 2013

Researchers complete first phase of landmark study on fungal complications of TB

The first phase of a landmark study of complications of tuberculosis - the first ever carried out in Africa - has been completed by researchers at Wythenshawe Hospital and the University of Manchester working with colleagues in Uganda.

30 Oct 2013

Researchers identify new drug for treating irritable bowel syndrome with constipation

An international team led by University of Adelaide researchers has identified the mechanism of pain relief of a new drug for treating Irritable Bowel Syndrome with Constipation (IBS-C), based on nonclinical studies, and quantified its effectiveness in pain relief in human trials.

30 Oct 2013

Disease/Infection News

Polyphor, Roche agree to develop and commercialize antibiotic for bacterial infections

Study: Single dose of HPV vaccine may be sufficient to protect cervical cancer

Study: Sugar intake is not directly associated with nonalcoholic fatty liver disease

VG Life Sciences' peptide awarded US patent for HIV treatment

Listeria's resistance to disinfectants

EcoHealth Alliance discovers new SARS-like coronavirus in Chinese horseshoe bats

GHIT Fund to host panel discussion to examine recent successes, setbacks in global health

HIV infection, not antiretroviral therapy associated with risk for atherosclerosis

Researchers find more accurate method to screen for meningococcal infection

Meclizine drug has the potential to treat certain infectious diseases and cancer

CytoDyn submits protocol to FDA for Phase IIb clinical trial of PRO 140

Canadian researchers contribute to the science of verotoxigenic E. coli and associated infections

Malaria elimination and insecticide resistance: an interview with Professor Hilary Ranson, Liverpool School of Tropical Medicine

MRSA cases continue to decline in VA medical centers

Identifying gaps in infection prevention practices may help improve patient safety, shows study

Mice exploit IRG proteins to create resistance mechanism against toxoplasma infection

Researchers develop new substance that quickly and effectively kills multi-resistant bacteria

Study looks at the feasibility of Xpert test for TB in real-life clinical setting in southern Africa

Researchers complete first phase of landmark study on fungal complications of TB

Researchers identify new drug for treating irritable bowel syndrome with constipation

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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