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Findings hold promise for development of therapies to fight different viral infections

The human body has the ability to ward off viruses by activating a naturally occurring protein at the cellular level, setting off a chain reaction that disrupts the levels of cholesterol required in cell membranes to enable viruses to enter cells.

18 Apr 2013

House-Senate 'endgame talks' face political hurdles, delays

The House GOP is moving slowly in naming negotiators to work through differences between the House- and Senate-passed budgets.

18 Apr 2013

IDRI, Medicago announce positive Phase I clinical trial results for avian flu pandemic vaccine

IDRI, a Seattle-based non-profit research organization that is a leading developer of adjuvants used in vaccines combating infectious disease, and Medicago Inc., a biopharmaceutical company focused on developing highly effective and competitive vaccines based on proprietary manufacturing technologies and Virus-Like Particles, today reported positive interim results from a Phase I clinical trial for an H5N1 Avian Influenza VLP vaccine candidate.

18 Apr 2013

Study: Half of Tamiflu prescriptions during 2009-10 influenza pandemic went unused in England

A new study concludes that approximately half of the prescriptions of Tamiflu during the 2009-10 influenza pandemic went unused in England.

18 Apr 2013

Research findings could lead to novel approaches for eliminating reservoirs of HIV-1

Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered how the protein that blocks HIV-1 from multiplying in white blood cells is regulated.

18 Apr 2013

Tacere Therapeutics submits TT-034 clinical trial application to Recombinant DNA Advisory Committee

RNAi-based therapeutics company Benitec Biopharma Limited today announced that the company's wholly owned US subsidiary, Tacere Therapeutics Inc., has submitted an application to the US National Institutes of Health's Recombinant DNA Advisory Committee.

18 Apr 2013

Study suggests strain with Haiti cholera mutations may increase severity of disease

The cholera strain that transferred to Haiti in 2010 has multiple toxin gene mutations that may account for the severity of disease and is evolving to be more like an 1800s version of cholera, reports a new Northwestern Medicine study.

17 Apr 2013

Registration open for 7th IAS Conference on HIV Pathogenesis, Treatment and Prevention

Registration for the 7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2013) -- which will take place in Kuala Lumpur, Malaysia, from June 30 to July 3, 2013 -- is now open through the conference webpage, which notes "[d]elegates are encouraged to register by 18 April 2013 ... to avoid the late fee surcharge, which begins on 19 April."

17 Apr 2013

Research shows how climate, environmental changes influence spread of dangerous viruses

How are human and animal diseases in general affected by the climate becoming "wilder, wetter and warmer"? Solveig Jore's doctoral research shows that the tick Ixodes ricinus has spread over larger geographical areas in Norway and that climate and environmental changes, access to host animals and demography affect tick distribution in Norway.

17 Apr 2013

Regional meeting to scale up collaborative TB/HIV activities begins in Maputo

"The regional meeting to scale up collaborative TB/HIV activities in Africa kicked off in Maputo last week with presentations scheduled for 14 African country representatives to share progress and challenges in confronting TB/HIV co-infection in the most highly impacted region of the world," the Center for Global Health Policy's "Science Speaks" blog reports.

17 Apr 2013

Researchers study how airborne infections spread in naturally ventilated hospital wards

The chance of infection in some hospital wards varies dramatically according to whether the nurses leave the windows open.

17 Apr 2013

New York Times examines indictments of Sierra Leone health officials over misuse of GAVI funding

The New York Times examines the indictment of 29 top health officials "by Sierra Leone's anticorruption agency on charges of misappropriating a half-million dollars in grants from" the GAVI Alliance.

17 Apr 2013

Misconduct by Zimbabwe U.N. official might have worsened 2008 cholera outbreak, U.N. tribunal finds

South Africa's Mail & Guardian examines the findings of a recent U.N. tribunal that found misconduct by the former head of the U.N. Development Programme office in Zimbabwe, which led to the 2009 wrongful dismissal of the head of the U.N.'s Office for the Coordination of Humanitarian Affairs after he warned about the potential for a cholera epidemic.

17 Apr 2013

Antiretroviral therapy does not affect resting energy expenditure in HIV-infected women

Studies have shown that about 10 percent of men infected with human immunodeficiency virus have an elevated resting energy expenditure.

17 Apr 2013

Flunisyn Phase 2a trial data shows positive results in elderly population

Following the widely publicised US Centers for Disease Control and Prevention report in February that the current season's flu vaccine is only 9% effective in the over-65 population, Immune Targeting Systems Limited, today announces positive data from a Phase 2a trial with the Company's lead pan-strain influenza A T-cell vaccine, Flunisyn, in the elderly population.

17 Apr 2013

Circumcision offers men some protection against HIV, discovers TGen-led study

Male circumcision reduces the abundance of bacteria living on the penis and might help explain why circumcision offers men some protection against HIV, according to a study led by the Translational Genomics Research Institute.

17 Apr 2013

Reports of H7N9 cases, deaths continue from across China

"Two more people have died in China from a new strain of bird flu, raising the death toll from the virus to 13, state media reported Sunday," the Associated Press reports.

16 Apr 2013

Production of synthetic artemisinin an attack against farmers currently growing the plant

"On Thursday, the founder of Amyris Biotech triumphantly announced production of 70 million doses of the anti-malarial compound artemisinin," Jim Thomas, research program director for ETC group, a technology watchdog that works with farmers' organizations, writes in The Guardian's "Poverty Matters" blog.

16 Apr 2013

Malaria strategies need to target at-risk populations, researchers say

New strategies are needed to fight malaria in countries with low prevalence, because "pockets of infection remain, mainly among men living or working outdoors," according to a paper published in The Lancet, BBC News reports.

16 Apr 2013

IRIN examines how mining industry in Mozambique increasing fears of HIV

IRIN examines how "[e]very mining boom brings the fear of a rising HIV infection rate, particularly in a country like Mozambique, where the estimated prevalence is already 11.3 percent."

16 Apr 2013

Disease/Infection News

Findings hold promise for development of therapies to fight different viral infections

House-Senate 'endgame talks' face political hurdles, delays

IDRI, Medicago announce positive Phase I clinical trial results for avian flu pandemic vaccine

Study: Half of Tamiflu prescriptions during 2009-10 influenza pandemic went unused in England

Research findings could lead to novel approaches for eliminating reservoirs of HIV-1

Tacere Therapeutics submits TT-034 clinical trial application to Recombinant DNA Advisory Committee

Study suggests strain with Haiti cholera mutations may increase severity of disease

Registration open for 7th IAS Conference on HIV Pathogenesis, Treatment and Prevention

Research shows how climate, environmental changes influence spread of dangerous viruses

Regional meeting to scale up collaborative TB/HIV activities begins in Maputo

Researchers study how airborne infections spread in naturally ventilated hospital wards

New York Times examines indictments of Sierra Leone health officials over misuse of GAVI funding

Misconduct by Zimbabwe U.N. official might have worsened 2008 cholera outbreak, U.N. tribunal finds

Antiretroviral therapy does not affect resting energy expenditure in HIV-infected women

Flunisyn Phase 2a trial data shows positive results in elderly population

Circumcision offers men some protection against HIV, discovers TGen-led study

Reports of H7N9 cases, deaths continue from across China

Production of synthetic artemisinin an attack against farmers currently growing the plant

Malaria strategies need to target at-risk populations, researchers say

IRIN examines how mining industry in Mozambique increasing fears of HIV

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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