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World could meet U.N. goal of almost ending malaria deaths by 2015, U.N. special envoy for malaria says

International efforts to fight malaria are "on track" to almost end malaria-related deaths by 2015, Ray Chambers, the U.N. secretary-general's special envoy for malaria, said on Monday, the Associated Press reports.

27 Apr 2011

Boehringer Ingelheim initiates enrollment in BI 201335 Phase 3 clinical trial for chronic HCV

Boehringer Ingelheim Pharmaceuticals, Inc. today announced that enrollment has commenced at North American sites in its pivotal Phase 3 clinical trial program for BI 201335, the Company's investigational, oral protease inhibitor for the treatment of chronic hepatitis C virus (HCV).

27 Apr 2011

Researchers develop protein-based inhibitor that can treat HPV

Human papillomavirus causes cervical cancer, the second most common cause of cancer death for women, and is a common cause of anogenital and some head and neck cancers.

27 Apr 2011

IQ Therapeutics completes dosing in IQNLF Phase I trial for anthrax

IQ Therapeutics has completed the dosing of antibody IQNLF in a Phase I clinical trial. A total of 36 healthy volunteers participated in the randomized, placebo controlled, double blind, single dose-escalating study, intended to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of IQNLF.

27 Apr 2011

New study sheds light on evolution of 2009 pandemic influenza A(H1N1) virus in Japan

Analysis of mutations of the 2009 pandemic influenza A(H1N1) virus by researchers at the RIKEN Omics Science Center (OSC) has revealed major genetic differences between the virus in its early phase of infection in Japan and in its peak phase. While yielding valuable clues on the genetic origins of drug resistance, the findings also pave the way toward the development of new diagnostic kits for detecting and preventing the spread of global pandemic diseases.

26 Apr 2011

New malaria initiative

According to the UN chief envoy for malaria a $5 billion campaign has saved several hundred thousand lives in recent years, keeping international efforts on track to virtually end deaths from the mosquito-borne disease by 2015. The UN reveals that about 780,000 people, mostly babies and toddlers in sub-Saharan Africa, now die from malaria annually, down from nearly 1 million in 2008.

26 Apr 2011

New angle in cause of tuberculosis discovered - scientists hopeful for new therapy

In a new study published Monday, researchers from the US have isolated the enzyme that allows tuberculosis to destroy lung tissue. This discovery could speed the search for treatments.

26 Apr 2011

Durata attains global rights for dalbavancin to treat abSSSI

Durata Therapeutics today announced the Company has attained worldwide rights for the development and commercialization of Durata's lead product, dalbavancin, a long-acting, intravenous (IV) lipoglycopeptide for the treatment of acute bacterial skin and skin structure infections (abSSSI). In December 2010, Durata acquired from RaQualia Pharma commercialization rights for dalbavancin in Japan.

26 Apr 2011

FDA grants Cepheid marketing clearance for Xpert Flu diagnostic test

Cepheid today announced it has received clearance from the U.S. Food & Drug Administration (FDA) to market Xpert® Flu. The diagnostic test, which runs on Cepheid's GeneXpert® System, simultaneously detects and differentiates Influenza A, Influenza B, and the 2009 H1N1 influenza virus in about one hour.

26 Apr 2011

PolyMedix defensin-mimetic antibiotic compounds show antimicrobial efficacy against anthrax

PolyMedix, Inc., a biotechnology company focused on developing new therapeutic drugs to treat patients with acute infectious diseases and cardiovascular disorders, announced today that several of its defensin-mimetic antibiotic compounds have shown antimicrobial efficacy in an animal model against the bacteria that causes anthrax.

26 Apr 2011

Merck receives Health Canada approval for GARDASIL to treat HPV in women upto age 45

Today, Merck announced that Health Canada has extended the indication of GARDASIL in women up to the age of 45. Merck's HPV vaccine is now approved for girls and women nine through 45 years of age for the prevention of cervical cancer, vulvar and vaginal cancers, precancerous lesions and genital warts caused by the Human Papillomavirus types 6, 11, 16, 18. Previously, GARDASIL was approved in girls and women nine through 26.

26 Apr 2011

AU health ministers highlight concerns over climate change's impact on health at CAMH5

African health ministers last week discussed their concerns about the health implications of climate change during the fifth African Union Conference of Ministers of Health in Windhoek, Namibia, PANA/Afrique en ligne reports. The conference, which focused on climate change, ended on Friday.

26 Apr 2011

WHO Africa regional director issues message for World Malaria Day

In a message marking Monday's World Malaria Day, Luis Gomes Sambo, WHO's regional director for Africa, noted that this year signifies the end of the U.N. decade to roll back malaria and "offers an opportunity for renewed commitment" to fight the disease, the Angola Press reports.

26 Apr 2011

U.S. President's Malaria Initiative releases fifth annual report

Each year, World Malaria Day is observed to call attention to the disease and to mobilize action to combat it. On this occasion, the President's Malaria Initiative, led by the U.S. Agency for International Development and implemented together with the Centers for Disease Control and Prevention, releases its fifth annual report, which describes the role and contributions of the U.S. Government in the effort to reduce the burden of malaria in Africa.

26 Apr 2011

World Malaria Day opinion pieces

Andrew Mitchell, Britain's secretary of state for international development, discusses the U.K.'s approach to combating malaria around the world in a post on the Guardian's "Poverty Matters Blog."

26 Apr 2011

African-American couples with HIV can benefit from health promotion interventions

Interventions to promote healthy behaviors, including eating more fruits and vegetables, increasing physical activity, and participating in cancer screenings, as well as prevention of HIV/sexually transmitted diseases, appear beneficial for African-American couples who are at high risk for chronic diseases, especially if one of the individuals is living with HIV.

26 Apr 2011

Study: More couple-based HIV counseling needed in South Africa

A new study of sexual risk behaviors within long-term couples in South Africa finds that HIV-positive people take almost as much risk in their sexual behavior when they know their partner is HIV-negative or don't know their status, as when they know their partner is already infected.

26 Apr 2011

NetGuarantee's inaugural transaction to help save lives from malaria

NetGuarantee, a new innovative finance facility, announces its first transaction with Zurich in North America, part of the Zurich Financial Services Group, to celebrate World Malaria Day today, April 25.

26 Apr 2011

Scientists identify key enzyme that destroys lung tissue in TB

Scientists have identified a key enzyme responsible for destroying lung tissue in tuberculosis, they report today in the Journal of Clinical Investigation. Drugs that inhibit this enzyme are already available, meaning that the finding could lead quickly to new treatments.

26 Apr 2011

Study: HIV infection linked to increased risk of heart failure

Patients with HIV infection without a prior history of coronary heart disease may be at a higher risk of developing heart failure, according to a report in the April 25 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

26 Apr 2011

Disease/Infection News

World could meet U.N. goal of almost ending malaria deaths by 2015, U.N. special envoy for malaria says

Boehringer Ingelheim initiates enrollment in BI 201335 Phase 3 clinical trial for chronic HCV

Researchers develop protein-based inhibitor that can treat HPV

IQ Therapeutics completes dosing in IQNLF Phase I trial for anthrax

New study sheds light on evolution of 2009 pandemic influenza A(H1N1) virus in Japan

New malaria initiative

New angle in cause of tuberculosis discovered - scientists hopeful for new therapy

Durata attains global rights for dalbavancin to treat abSSSI

FDA grants Cepheid marketing clearance for Xpert Flu diagnostic test

PolyMedix defensin-mimetic antibiotic compounds show antimicrobial efficacy against anthrax

Merck receives Health Canada approval for GARDASIL to treat HPV in women upto age 45

AU health ministers highlight concerns over climate change's impact on health at CAMH5

WHO Africa regional director issues message for World Malaria Day

U.S. President's Malaria Initiative releases fifth annual report

World Malaria Day opinion pieces

African-American couples with HIV can benefit from health promotion interventions

Study: More couple-based HIV counseling needed in South Africa

NetGuarantee's inaugural transaction to help save lives from malaria

Scientists identify key enzyme that destroys lung tissue in TB

Study: HIV infection linked to increased risk of heart failure

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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