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Boehringer Ingelheim's BI 201335 new data against HCV highlighted at EASL meeting

New data presented today at the International Liver CongressTM 2011, the 46th Annual Meeting of the European Association for the Study of the Liver, in Berlin, highlighted the efficacy of Boehringer Ingelheim's once-daily oral protease inhibitor BI 201335, in both treatment-naïve and -experienced patients with chronic genotype-1 hepatitis C virus infection. Genotype-1 HCV is the most challenging genotype of HCV to treat.

2 Apr 2011

Boehringer Ingelheim advances into Phase 3 clinical trial of BI 201335

Boehringer Ingelheim today announced a preview of the study designs for the pivotal Phase 3 clinical trials evaluating BI 201335, its investigational once-daily oral protease inhibitor, in both treatment-naive and -experienced patients with chronic genotype-1 hepatitis C virus, the most challenging genotype to treat.

2 Apr 2011

Series of new clinical trials confirm range of viable treatment options for HCV patients

Highly anticipated data from a number of clinical trials presented for the first time at the International Liver CongressTM confirmed that a range of new proteases inhibitors will help treat patients who have previously failed therapy for the treatment of chronic hepatitis C.

2 Apr 2011

Recent releases in Global Health

A Lancet Infectious Diseases editorial describes the growing public concerns over a global rise in antimicrobial resistance. "Bearing in mind that our objective is to contain antibiotic resistance rather than eradicate it, several policies could be adopted to help guarantee a future for antibiotics," the editorial states, adding, "We need reliable data to tackle antibiotic resistance.

2 Apr 2011

House subcommittee approves bill calling for report on USAID's efforts to address Haiti's cholera outbreak

The House Foreign Affairs Subcommittee on the Western Hemisphere on Thursday "approved by voice vote a bill (HR 1016) that would require the Obama administration to report to Congress within six months on the handling of U.S. funds for combating a cholera outbreak that occurred after last year's earthquake in Haiti," CQ reports.

2 Apr 2011

Blocking TNF-related apoptosis-inducing ligand pathway partially reconstitutes HBV-specific T cells

A new study presented today at the International Liver Congress shows a novel pathway where activated natural killer (NK) cells expressing death ligands may excessively down-modulate the antiviral immune response in chronic HBV patients.

2 Apr 2011

Encouraging early data from HCV vaccine phase I trial presented at International Liver Congress

Early data from phase I trials of an HCV vaccine presented today at the International Liver CongressTM show encouraging results, with high immunogenicity and good safety profile.

2 Apr 2011

Researcher to host live experiment to show effectiveness of antimicrobial copper in preventing MRSA

Following research by Professor Bill Keevil at the University of Southampton showing that copper can significantly reduce the presence of MRSA, the University, in partnership with the Copper Development Association, is hosting a live experiment that will show the effectiveness of antimicrobial copper in preventing MRSA infections.

2 Apr 2011

South Africa, Lesotho, Swaziland form alliance to fight MDR-TB

Health ministers from Lesotho, Swaziland and South Africa said they have formed an alliance to fight drug-resistant tuberculosis, Deutsche Presse-Agentur/M&C reports.

1 Apr 2011

USAID Administrator testifies before State, Foreign Ops subcommittee about FY12 budget, expresses concerns about FY11 budget cuts

In a hearing regarding the FY12 budget before the House Appropriations State and Foreign Operations subcommittee earlier this week, USAID Administrator Rajiv Shah highlighted the possible impact of the FY11 budget cuts currently being debated in Congress, Foreign Policy's "The Cable" blog reports.

1 Apr 2011

Pediatrician suggests tips to combat allergic symptoms

One of the problems that parents may have during the springtime is deciphering whether their children's sneezing is due to a cold or allergies.

1 Apr 2011

Results of Boehringer Ingelheim's BI 201335 study presented at Annual Meeting of EASL

New data presented today at the 46th Annual Meeting of the European Association for the Study of the Liver demonstrate the antiviral activity of Boehringer Ingelheim's once-daily oral protease inhibitor, BI 201335, in both treatment-naive and -experienced patients with chronic genotype-1 hepatitis C virus, the most challenging genotype of HCV to treat.

1 Apr 2011

eGlobalTech receives HRSA contract to support enterprise-wide Call Center Study

eGlobalTech announced today that it has been awarded a prime contract with the Health Resources and Services Administration to support an enterprise-wide Call Center Study.

1 Apr 2011

New guidelines to eliminate bloodstream infections in patients with intravenous catheters

New guidelines, released by the Centers for Disease Control and Prevention and the Healthcare Infection Control Practices Advisory Committee outline steps to eliminate bloodstream infections in patients with intravenous catheters, which are among the most deadly and costly healthcare-associated infections.

1 Apr 2011

Scientists develop new experimental diagnostic test to distinguish infection from disease

A potential new experimental diagnostic test able to quickly distinguish individuals with active tuberculosis from those with latent TB infection has been developed. If the preliminary results of the study will be confirmed in a larger population sample, the new diagnostic system could allow more effective strategies to control the spread of the re-emerging pathology.

1 Apr 2011

New findings from two modeling studies can help reduce HCV-related deaths in Europe

New findings from two modeling studies presented at the International Liver Congress support the call to action from medical experts and patients in relation to the challenge health inequalities represent in the diagnosis and access to HCV treatment.

1 Apr 2011

California State Controller urges Merck, Tibotec and ViiV to reduce AIDS drug prices

Today AIDS Healthcare Foundation (AHF) announced that California State Controller John Chiang has sent letters to the CEOs of Merck & Co., Tibotec Therapeutics and ViiV Healthcare, asking the companies to reduce the price of their HIV/AIDS medications for California and its AIDS Drug Assistance Program (ADAP).

1 Apr 2011

Lymphocyte-hepatocyte interactions: Hepatitis C virus changes the rules

New data presented at the International Liver CongressTM today show the existence of novel interactions between T cells and hepatocytes that are regulated by HCV infection, providing a novel understanding of how HCV persists in the liver.

1 Apr 2011

HIV prevention, treatment must be expanded in Asia-Pacific, delegates at regional meeting say

More needs to be done to prevent the spread of HIV/AIDS and increase access to treatments for patients living with the disease, according to representatives from 24 Asia-Pacific countries attending a regional United Nations meeting in Bangkok this week, VOA News reports.

1 Apr 2011

Potential HIV vaccine component undergoes dramatic protein rearrangement

An international study headed by a UC Davis scientist describes how a component of a potential HIV vaccine opens like a flower, undergoing one of the most dramatic protein rearrangements yet observed in nature. The finding could reveal new targets for vaccines to prevent HIV infection and AIDS. A paper describing the work was published online this week in the journal Proceedings of the National Academy of Sciences.

1 Apr 2011

Disease/Infection News

Boehringer Ingelheim's BI 201335 new data against HCV highlighted at EASL meeting

Boehringer Ingelheim advances into Phase 3 clinical trial of BI 201335

Series of new clinical trials confirm range of viable treatment options for HCV patients

Recent releases in Global Health

House subcommittee approves bill calling for report on USAID's efforts to address Haiti's cholera outbreak

Blocking TNF-related apoptosis-inducing ligand pathway partially reconstitutes HBV-specific T cells

Encouraging early data from HCV vaccine phase I trial presented at International Liver Congress

Researcher to host live experiment to show effectiveness of antimicrobial copper in preventing MRSA

South Africa, Lesotho, Swaziland form alliance to fight MDR-TB

USAID Administrator testifies before State, Foreign Ops subcommittee about FY12 budget, expresses concerns about FY11 budget cuts

Pediatrician suggests tips to combat allergic symptoms

Results of Boehringer Ingelheim's BI 201335 study presented at Annual Meeting of EASL

eGlobalTech receives HRSA contract to support enterprise-wide Call Center Study

New guidelines to eliminate bloodstream infections in patients with intravenous catheters

Scientists develop new experimental diagnostic test to distinguish infection from disease

New findings from two modeling studies can help reduce HCV-related deaths in Europe

California State Controller urges Merck, Tibotec and ViiV to reduce AIDS drug prices

Lymphocyte-hepatocyte interactions: Hepatitis C virus changes the rules

HIV prevention, treatment must be expanded in Asia-Pacific, delegates at regional meeting say

Potential HIV vaccine component undergoes dramatic protein rearrangement

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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