Disease/Infection News

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Exciton, ULURU sign agreement to develop and market Altrazeal exSALT product

ULURU Inc. announced today that it has signed a Binding Letter of Intent with Exciton Technologies Inc. to develop and market a product that will combine Altrazeal® with Exciton's proprietary exSALT™ Antimicrobial Technology.

20 Jan 2011

Apricus Bio's MycoVa demonstrates 'non-inferiority' for treatment of onychomycosis compared to Loceryl

Apricus Biosciences, Inc. today announced that an additional analysis conducted on behalf of the Company has shown that MycoVa™ has successfully demonstrated 'non-inferiority' for the treatment of onychomycosis (commonly referred to as nail fungus), compared to the current standard of care in Europe for topical therapy, Loceryl®.

20 Jan 2011

Small molecules may inhibit entry of Ebola into human cells

Ebola, a virus that causes deadly hemorrhagic fever in humans, has no known cure or vaccine. But a new study by University of Illinois at Chicago scientists has uncovered a family of small molecules which appear to bind to the virus's outer protein coat and may inhibit its entry into human cells.

20 Jan 2011

Study: HIV-positive head and neck cancer patients respond well to radiation therapy treatments

HIV-positive head and neck cancer patients respond well to radiation therapy treatments and experience similar toxicity rates as non-HIV-positive patients, despite prior reports to the contrary, according to a study in the January issue of the International Journal of Radiation Oncology•Biology•Physics, an official journal of the American Society for Radiation Oncology.

19 Jan 2011

Scientists determine protein structure that delivers genetic material of HIV to human cells

A team of scientists at The Scripps Research Institute and the University of Virginia has determined the structure of the protein package that delivers the genetic material of the human immunodeficiency virus to human cells.

19 Jan 2011

Study finds link between public transport and risk of catching ARI

You are six times more likely to end up at the doctors with an acute respiratory infection if you have recently used a bus or tram — but those who use buses or trams daily might well be somewhat protected compared with more occasional users.

19 Jan 2011

Legionnaires’ disease scare in Bali: Australian tourists warned

Commonwealth chief medical officer Jim Bishop has warned Australians who have returned from Bali on an outbreak of Legionnaires’ disease on the popular Indonesian resort island. The Australian health authorities knew of 11 cases of Legionnaires’ disease detected in Victorians and Western Australians after holidays in the Kuta area of Bali between August 2010 and January 2011.

19 Jan 2011

Malaria parasite caught in action on film for the first time

Australian researchers have managed to take pictures of microscopic malaria parasite as it invades a human red blood cell. This will provide a deeper understanding of the parasite’s behaviour and may help fight it. Up to 10% of the world’s population contract malaria every year and a million people, mostly pregnant women and children, die as a result of the parasite transmitted by infected mosquitoes.

19 Jan 2011

Race and region play major role in health outcomes of people infected with HIV

Women, nonwhites, and people in the southern United States who were newly infected with HIV and followed for an average of four years experienced greater HIV/AIDS-related morbidity compared to men and people of other races living in other regions of the country. The findings, published in the February 15 issue of The Journal of Infectious Diseases, underscore the urgent need to improve the health of these populations in order to reduce HIV-related morbidity and mortality in the U.S.

19 Jan 2011

Transplant surgeons routinely use fewer organs from high-risk donors

As a response to a 2007 episode in which four patients in Chicago were transplanted with organs from a single donor unknowingly infected with HIV — the only such episode in 20 years — one-third of transplant surgeons in the United States "overreacted" and began routinely using fewer organs from high-risk donors, new research from Johns Hopkins finds.

19 Jan 2011

Collaborative study may lead to improved influenza vaccine and vaccines for other respiratory virus infections

A collaborative project between researchers at the Trudeau Institute and their colleagues at St. Jude Children's Research Hospital in Memphis, Tenn., offers new insights that may lead to an improved strategy to protect against the influenza virus and other viruses that infect the respiratory tract.

19 Jan 2011

Dr. Kathleen receives NSF grant to measure how climate change will impact risk of malaria, dengue fever

Thanks to a $250,000 National Science Foundation grant we may soon know how climate change will impact our risk of malaria and dengue fever. Dr. Kathleen Schreiber, professor of geography at Millersville University of Pennsylvania, received the grant from the NSF sponsored Vector-Borne Disease Project to measure how environmental temperature change influences the transmission and disease risk of the two diseases.

19 Jan 2011

Dextran-coated onto iron oxide nanoparticles can detect cholera toxin: Study

A complex sugar may someday become one of the most effective weapons to stop the spread of cholera, a disease that has claimed thousands of lives in Haiti since the devastating earthquake last year.

19 Jan 2011

Researchers create biyouyanagin compound library

Using chemical compounds found in a Japanese plant as a lead and the clever application of ultraviolet light, a Scripps Research Institute team has created a unique library of dozens of synthetic compounds to test for biomedical potential. Already, one of the compounds has shown great promise in inhibiting replication of HIV particles and fighting inflammation.

19 Jan 2011

Convalescent plasma therapy may reduce mortality rate in patients with H1N1 infection: Study

A study published in the February 15 issue of Clinical Infectious Diseases suggests that convalescent plasma may reduce the death rate in patients severely ill with this type of influenza.

19 Jan 2011

Meganucleases used to prevent HSV-1 infection

Cellectis, announced today that scientists from Cellectis therapeutics, the French National Center For Medical Research (CNRS) and Institut de la Vision (Paris) have used its proprietary meganucleases to successfully prevent infection of cultured cells by a Herpes Simplex virus (HSV-1).

19 Jan 2011

BSi and OMJPI enter development agreement for novel neurological and psychiatric disease therapeutics

The Johns Hopkins Brain Science Institute (BSi) announced today that it has entered into an agreement with Ortho-McNeil-Janssen Pharmaceuticals Inc. (OMJPI) to advance the development of novel therapeutics for neurological and psychiatric diseases.

19 Jan 2011

Healthy teeth and gums may reduce risk for pneumonia, chronic obstructive pulmonary disease

Maintaining periodontal health may contribute to a healthy respiratory system, according to research published in the Journal of Periodontology. A new study suggests that periodontal disease may increase the risk for respiratory infections, such as chronic obstructive pulmonary disease (COPD) and pneumonia.

19 Jan 2011

New project on developing countermeasures for natural and intentional exposure to disease pathogens

Researchers at Dana-Farber Cancer Institute have received a $5.6 million grant from the Defense Advanced Research Projects Agency (DARPA) and the Army Research Office (ARO) to develop transient immunity against known, unknown, naturally occurring, or engineered disease-causing pathogens. The ultimate goal is to develop a viable countermeasure to an unknown pathogen within seven days of receiving it in a laboratory.

19 Jan 2011

WHO Director-General opens executive board session with calls for reform

Kicking off a nine-day annual WHO executive board meeting Monday, WHO Director-General Margaret Chan called for the board to consider areas where the agency can redirect resources in a more targeted manner so as to achieve greater outcomes, Reuters reports.

19 Jan 2011

Disease/Infection News

Exciton, ULURU sign agreement to develop and market Altrazeal exSALT product

Apricus Bio's MycoVa demonstrates 'non-inferiority' for treatment of onychomycosis compared to Loceryl

Small molecules may inhibit entry of Ebola into human cells

Study: HIV-positive head and neck cancer patients respond well to radiation therapy treatments

Scientists determine protein structure that delivers genetic material of HIV to human cells

Study finds link between public transport and risk of catching ARI

Legionnaires’ disease scare in Bali: Australian tourists warned

Malaria parasite caught in action on film for the first time

Race and region play major role in health outcomes of people infected with HIV

Transplant surgeons routinely use fewer organs from high-risk donors

Collaborative study may lead to improved influenza vaccine and vaccines for other respiratory virus infections

Dr. Kathleen receives NSF grant to measure how climate change will impact risk of malaria, dengue fever

Dextran-coated onto iron oxide nanoparticles can detect cholera toxin: Study

Researchers create biyouyanagin compound library

Convalescent plasma therapy may reduce mortality rate in patients with H1N1 infection: Study

Meganucleases used to prevent HSV-1 infection

BSi and OMJPI enter development agreement for novel neurological and psychiatric disease therapeutics

Healthy teeth and gums may reduce risk for pneumonia, chronic obstructive pulmonary disease

New project on developing countermeasures for natural and intentional exposure to disease pathogens

WHO Director-General opens executive board session with calls for reform

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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