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Queensland’s flooded residents warned against insect bites

The Queensland Health authorities have issued warnings to residents and tourists in the Emerald region regarding mosquitoes, biting midges (commonly known as sand flies) and black flies in areas affected by flooding. The Council insect control programs are helping with reducing the number of insects, say authorities but people still need to protect themselves to reduce the risk of being bitten in the next few weeks.

6 Jan 2011

VEREGEN Ointment added as new therapeutic option in 2010 CDC STD Treatment Guidelines

PharmaDerm, a division of Nycomed US Inc., announced today that VEREGEN (sinecatechins) Ointment, 15%, a topical medication for the treatment of external genital and perianal warts, has been added as a new therapeutic option in the 2010 Centers for Disease Control and Prevention Sexually Transmitted Diseases Treatment Guidelines.

6 Jan 2011

Profectus BioSciences commences GENEVAX IL-12 phase 1 study for HIV

Profectus BioSciences, a leader in the development of therapeutic and preventive vaccines against infectious diseases and cancers, and the AIDS Clinical Trials Group announced today the initiation of a phase 1 study of Profectus' multi-antigen HIV plasmid DNA vaccine administered with various doses of GENEVAX™ interleukin-12 pDNA adjuvant and delivered using the electroporation based TriGrid™delivery system developed by Ichor Medical Systems.

6 Jan 2011

Studies show XIFAXAN 550 mg tablets demonstrate significant relief of global IBS symptoms

Salix Pharmaceuticals, Ltd. today announced the New England Journal of Medicine has published results from TARGET 1 and TARGET 2, the Company's two pivotal Phase 3 efficacy and safety studies of XIFAXAN (rifaximin) 550 mg tablets for the treatment of Irritable Bowel Syndrome without constipation, or Non-C IBS.

6 Jan 2011

Impact of flu vaccine opt-out is being seen as A(H1N1) returns to Europe

As the UK and a number of European countries are now experiencing epidemics of influenza, including A(H1N1) which was the 2009 pandemic virus, the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) warns that the consequences of non-vaccination could emerge as a new flu emergency and are calling for greater efforts to encourage vaccination, not only for at risk groups but also health care workers.

6 Jan 2011

Indian drugmaker seeks to make, sell generic version of Pfizer's HIV drug

The Indian drugmaker Natco Pharma "said Wednesday it has informed Pfizer Inc. that it wants to make and sell a low-cost generic version of the U.S. company's [drug] maraviroc for treating the HIV infection under a so-called 'compulsory license'," Dow Jones Newswires/Smart Money reports.

6 Jan 2011

Scientists identify prognostic biomarker to treat patients with HCV

Scientists at Inserm and Institut Pasteur have performed biomarker discovery on patients being treated for chronic hepatitis C infection. Their work, published in The Journal of Clinical Investigation, demonstrates that the plasma levels of the protein IP-10 predict, prior to treatment initiation, the efficacy of treatment with pegylated-interferon and ribavirin.

6 Jan 2011

Study sheds light on quantity of MRSA colonization, relationship between quantities at different sites

A new study from Rhode Island Hospital now sheds light on both the quantity of MRSA at different body sites and the relationship between the quantities at different sites.

6 Jan 2011

Columbia research team identifies bacteria may play a key role in atherosclerosis

Dr. Emil Kozarov and a team of researchers at the Columbia University College of Dental Medicine have identified specific bacteria that may have a key role in vascular pathogenesis, specifically atherosclerosis, or what is commonly referred to as "hardening of the arteries" - the number one cause of death in the United States.

6 Jan 2011

Study provides new insights into how viruses establish chronic infections

Walter and Eliza Hall Institute researchers in Melbourne, Australia, have discovered how a key viral gene helps viruses evade early detection by the immune system. Their finding is providing new insights into how viruses are able to establish chronic infections, leading scientists to reevaluate their approaches to viral vaccine development.

6 Jan 2011

Bacteria adopt defence strategy to promote antibiotic resistance

Genetic resistance to antibiotics is not the only trick bacteria use to resist eradication- they also have a second defence strategy known as persistence that can kick in.

6 Jan 2011

ODS enters license agreement with Enox Biopharma to develop novel treatment for periodontal disease

Enox Biopharma, a leader in the development of innovative solutions for infections associated with medical devices, and Ortho Dental Solutions LTD today announced an execution of an exclusive royalty bearing license agreement under which Enox Biopharma shall grant Ortho Dental Solutions LTD rights to patent application and knowhow for use in developing novel therapies limited in use for dental and gum diseases.

6 Jan 2011

New resolvin reduces levels of pro-inflammatory molecules and cells in inflammation caused by E. coli

Inflammation is a protective response to invading microbes and tissue damage. Upon microbe clearance from the body or completion of wound healing, the inflammatory response must be dampened down.

5 Jan 2011

Men are more willing to receive HPV vaccine, trend may help reduce cancer deaths

Men are more willing to receive human papillomavirus vaccine when they learn the vaccine can prevent cancer, according to a recent University of North Carolina at Chapel Hill study.

5 Jan 2011

P. gingivalis infection accelerates inflammation and atherosclerosis in the innominate artery

Atherosclerosis is the leading cause of death in the developed world. While a number of risk factors for atherosclerosis have been defined, scientists continue to study other possible risk factors for this disease. Recent epidemiological and experimental studies link infectious agents with the development of inflammatory atherosclerosis. A hallmark of chronic infection with the oral pathogen Porphyromonas gingivalis is the induction of a chronic inflammatory response.

5 Jan 2011

Insecticidal nets do not always work against diseases transmitted by insect bites

Longlasting insecticidal nets yielded an important breakthrough in malaria prevention, but this does not automatically mean they always work against diseases transmitted by insect bites. Against the transmission of kala azar disease in India and Nepal they did not have an effect. This was reported by an international group of researchers, led by Marleen Boelaert of the Institute of Tropical Medicine Antwerp, in the reputed British Medical Journal.

5 Jan 2011

Indian government rejects Abbott's patent application for second-line ARV

India's patent office "has rejected American drug maker Abbott Laboratories' patent application for an HIV combination drug, allowing low-cost local drug makers to make and sell their generic versions in India and other countries where the medicine is not patented," Economic Times reports (1/4).

5 Jan 2011

Dongsheng obtains exclusive sales rights of Thymosin Alpha 1 Injection in China

Dongsheng Pharmaceutical International Co., Ltd. announced today that it has obtained the exclusive sales rights of Thymosin Alpha 1 Injection in 19 provinces in China from Shanghai Biochemistry Pharmaceutical Co. I.

5 Jan 2011

Two doses of varicella vaccine provide higher antibody levels than one

When vaccinating children against varicella, researchers at Yale School of Medicine have found, two doses are better than one. In fact, the odds of developing chicken pox were 95 percent lower in children who had received two doses of the vaccine compared with those who had received only one dose.

5 Jan 2011

Researchers develop new hand-held instrument for glaucoma screening

A new hand-held instrument involving a system of micro-force sensors, specially designed microchips, and math-based programmed procedures has been designed by researchers at the UA College of Engineering. The easy-to-use probe gently rubs the eyelid and can be used at home, threatening to replace painful eye drops and the need for a sterilized sensor.

5 Jan 2011

Disease/Infection News

Queensland’s flooded residents warned against insect bites

VEREGEN Ointment added as new therapeutic option in 2010 CDC STD Treatment Guidelines

Profectus BioSciences commences GENEVAX IL-12 phase 1 study for HIV

Studies show XIFAXAN 550 mg tablets demonstrate significant relief of global IBS symptoms

Impact of flu vaccine opt-out is being seen as A(H1N1) returns to Europe

Indian drugmaker seeks to make, sell generic version of Pfizer's HIV drug

Scientists identify prognostic biomarker to treat patients with HCV

Study sheds light on quantity of MRSA colonization, relationship between quantities at different sites

Columbia research team identifies bacteria may play a key role in atherosclerosis

Study provides new insights into how viruses establish chronic infections

Bacteria adopt defence strategy to promote antibiotic resistance

ODS enters license agreement with Enox Biopharma to develop novel treatment for periodontal disease

New resolvin reduces levels of pro-inflammatory molecules and cells in inflammation caused by E. coli

Men are more willing to receive HPV vaccine, trend may help reduce cancer deaths

P. gingivalis infection accelerates inflammation and atherosclerosis in the innominate artery

Insecticidal nets do not always work against diseases transmitted by insect bites

Indian government rejects Abbott's patent application for second-line ARV

Dongsheng obtains exclusive sales rights of Thymosin Alpha 1 Injection in China

Two doses of varicella vaccine provide higher antibody levels than one

Researchers develop new hand-held instrument for glaucoma screening

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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