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Mathematical model projects potential impact of current tools fighting malaria in Africa

Current tools for combating malaria, such as artemisinin-based combination therapy (ACT) and increasing coverage of long-lasting insecticide treated nets (LLINs) insecticide-treated bednets (ITN) "could dramatically reduce the burden of malignant malaria on parts of Africa if a comprehensive, sustained intervention programme were in place," according to a study published this week in PLoS Medicine, CORDIS News reports.

16 Aug 2010

Nearly 1100 foodborne outbreaks reported nationally in 2007: CDC analysis

A total of 1,097 foodborne disease outbreaks were reported in 2007 to the Centers for Disease Control and Prevention, according to a CDC analysis. State investigators reported 21,244 illnesses and 18 deaths as a result of these outbreaks. The report also provides the most recent data on how many illnesses were linked to specific types of foods.

13 Aug 2010

Activists, care providers, patients protest against Senator Nelson's silence on AIDS drug program

While Florida continues to add up to 300 people each month to its waiting list for its AIDS Drug Assistance Program, scores of AIDS activists, care providers and patients will gather at a protest and press briefing hosted by AIDS Healthcare Foundation, Friday, August 13th at 12:00 Noon outside the Tampa offices of United States Senator Bill Nelson (D, FL).

13 Aug 2010

National organization releases “Lessons from the Frontlines” report on H1N1

The Canadian Medical Association (CMA), the College of Family Physicians of Canada (CFPC), and the National Specialty Society of Community Medicine (NSSCM) today released Lessons from the Frontlines, a collaborative report on H1N1 describing the physician experience on the frontlines of the pandemic.

13 Aug 2010

Mount Sinai receives grant from NIH to continue research on food allergy

Mount Sinai School of Medicine today announced that the National Institutes of Health (NIH) has renewed its funding of the Consortium of Food Allergy Research (CoFAR), providing an additional $29.9 million toward genetic research and the prevention and treatment of food allergy. Mount Sinai is the primary research site for CoFAR, leading seven other institutions around the country.

13 Aug 2010

Combination of fungi, insecticides can combat malaria mosquitoes: Research

A combination of fungal spores and chemical insecticides are an effective way of combating insecticide-resistant malaria mosquitoes. Researchers at Wageningen UR and from Benin, West Africa, have shown that fungi and insecticides reinforce each other´s efficacy, and that the effect of using a combination of both is greater than the sum of using the two methods separately. Their article in the August edition of PLoS One (Public Library of Science) claims that biological and chemical methods of fighting malaria can and should be used together.

13 Aug 2010

Floods: U.N. issues $459.7M appeal for Pakistan, China concerned about disease outbreaks after mudslides

The U.N. appealed for $459.7 million on Wednesday "to aid flood victims in Pakistan as the magnitude of the disaster widened, with about one-fifth of the country submerged and the annual monsoon season still potent," the New York Times reports (MacFarquhar, 8/11).

13 Aug 2010

A*STAR's Singapore Immunology Network, Institut M-rieux and bioM-rieux partner in TB research

An investment of S$3 million is being pumped into tuberculosis (TB) research by A*STAR's Singapore Immunology Network (SIgN), bioindustrial group Institut M-rieux and its in vitro diagnostics company bioM-rieux. The project, which involves setting up a joint laboratory in Biopolis, Singapore aims to investigate and identify novel biomarkers that could allow early identification of individuals at risk of TB disease development and disease reactivation. This could lead to better diagnosis and treatment for the highly contagious disease.

13 Aug 2010

Severe inflammatory response to initial UTI causes bladder damage: Research

The immune system may open the door to recurrent urinary tract infections (UTIs) by overdoing its response to an initial infection, researchers at Washington University School of Medicine in St. Louis have found.Researchers showed in mice that severe inflammatory responses to an initial UTI cause bladder damage and allow infection to persist longer. After one to two weeks of infection, the bladder wall undergoes additional changes that leave mice more vulnerable to later infection. Suppressing the immune system during initial infection decreases these vulnerabilities, they report Aug. 12 in PLoS Pathogens.

13 Aug 2010

Exposure to immune proteins during pregnancy increases risk for schizophrenia in offspring

Infections like the flu are common occurrences during pregnancy, and research has shown that children born to mothers who suffered from flu, viruses and other infections during pregnancy have about a 1.5 to 7 times increased risk for schizophrenia. A new study out of Temple University examines what's behind that link.

13 Aug 2010

HIV infected injection drug users likely to have kidney disease: Study

Poor kidney function is common among injection drug users, particularly those with HIV, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). The results suggest that clinicians should monitor the kidney function of HIV-infected injection drug users and consider them candidates for medical treatments to protect their kidneys when appropriate.

13 Aug 2010

Novavax announces positive results from pre-clinical toxicology study of RSV vaccine candidate

Novavax, Inc. reported today that results from a pre-clinical toxicology study of its vaccine candidate to prevent respiratory syncytial virus, showed the vaccine to be safe and well-tolerated at all doses tested. Novavax's vaccine uses highly purified recombinant particles of RSV-F fusion protein normally found in the virus. There is currently no approved vaccine to prevent RSV infection.

13 Aug 2010

WHO releases H1N1 Emergency Committee roster

Five of the 15 experts advising the WHO on H1N1 (swine flu) had ties to the pharmaceutical industry, "including for flu vaccine research," according to the Emergency Committee members' list released by the agency Wednesday, Agence France-Presse reports.

13 Aug 2010

Superbug purportedly from Asia on the rise in UK & Australia

British scientists have claimed that a new gene called New Delhi metallo-beta-lactamase, or NDM-1 has emerged that makes the bacteria resistant to almost all antibiotics. India has rejected the claim that it is the source of this superbug. Cases have been detected in the UK and Australia and are on the rise in the UK.

12 Aug 2010

Pharmasset receives fast track designation from FDA for PSI-7977

Pharmasset, Inc. has received fast track designation from the U.S. Food and Drug Administration for PSI-7977 for the treatment of chronic hepatitis C virus infection. PSI-7977 is an oral uridine nucleotide analog polymerase inhibitor of HCV. Pharmasset recently completed dosing in a 28 day Phase 2a trial to evaluate PSI-7977 in combination with Pegasys (pegylated interferon) plus Copegus (ribavirin) in treatment-naive patients chronically infected with HCV genotype 1.

12 Aug 2010

FDA grants BioMimetic Therapeutics orphan drug designation for rhPDGF-BB in treatment of OCD

BioMimetic Therapeutics, Inc. today announced that it has received orphan drug designation from the Food and Drug Administration for its protein therapeutic, recombinant human platelet derived growth factor, to be used in conjunction with autograft and/or commercially available osteochondral allograft for the treatment of osteochondritis dissecans of the knee, elbow or ankle.

12 Aug 2010

VSee, Mandy Moore, Nothing But Nets, and UN Foundation partner for video townhall on malaria in Africa

On August 12th at 2:00 p.m. ET, Mandy Moore joins Nothing But Nets™ and PSI for a video townhall on malaria in Africa, broadcast on Facebook®. The video conferencing service will be provided by VSee Lab, Inc. and Ustream, and the event is hosted by Derrick Ashong, one of Katalyst Media's Social Media Envoys. This is an opportunity to question Mandy Moore and learn about sending nets and saving lives. Become a fan of Nothing But Nets on Facebook and join the discussion.

12 Aug 2010

News outlets look at how H1N1 will inform WHO's future outbreak response

Following the WHO's decision on Tuesday to declare the H1N1 (swine flu) pandemic over, several news outlets reviewed the emergence of the virus around the world, exploring how some of the lessons learned from H1N1 could assist the WHO's handling of future outbreaks.

12 Aug 2010

Newly identified gene enabling bacterial resistance to most antibiotics found in South Asia, U.K., study finds

A study published online Wednesday in Lancet Infectious Diseases identifies a gene that enables bacteria to resist most antibiotics and calls for better global surveillance of multi-drug resistant bacteria, the Associated Press reports (8/11).

12 Aug 2010

Emergency Committee Members report on post-pandemic period of H1N1

The world is no longer in phase 6 of influenza pandemic alert. We are now moving into the post-pandemic period. The new H1N1 virus has largely run its course.These are the views of members of the Emergency Committee, which was convened earlier today by teleconference.The Committee based its assessment on the global situation, as well as reports from several countries that are now experiencing influenza. I fully agree with the Committee's advice.

12 Aug 2010

Disease/Infection News

Mathematical model projects potential impact of current tools fighting malaria in Africa

Nearly 1100 foodborne outbreaks reported nationally in 2007: CDC analysis

Activists, care providers, patients protest against Senator Nelson's silence on AIDS drug program

National organization releases “Lessons from the Frontlines” report on H1N1

Mount Sinai receives grant from NIH to continue research on food allergy

Combination of fungi, insecticides can combat malaria mosquitoes: Research

Floods: U.N. issues $459.7M appeal for Pakistan, China concerned about disease outbreaks after mudslides

A*STAR's Singapore Immunology Network, Institut M-rieux and bioM-rieux partner in TB research

Severe inflammatory response to initial UTI causes bladder damage: Research

Exposure to immune proteins during pregnancy increases risk for schizophrenia in offspring

HIV infected injection drug users likely to have kidney disease: Study

Novavax announces positive results from pre-clinical toxicology study of RSV vaccine candidate

WHO releases H1N1 Emergency Committee roster

Superbug purportedly from Asia on the rise in UK & Australia

Pharmasset receives fast track designation from FDA for PSI-7977

FDA grants BioMimetic Therapeutics orphan drug designation for rhPDGF-BB in treatment of OCD

VSee, Mandy Moore, Nothing But Nets, and UN Foundation partner for video townhall on malaria in Africa

News outlets look at how H1N1 will inform WHO's future outbreak response

Newly identified gene enabling bacterial resistance to most antibiotics found in South Asia, U.K., study finds

Emergency Committee Members report on post-pandemic period of H1N1

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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