Disease/Infection News

RSS

New model for scaling up treatment, prevention of HIV amongst IDUs

Against the backdrop of some of the globe's fastest growing HIV epidemics in Eastern Europe and Central Asia, a report launched today at the XVIII International AIDS conference in Vienna makes the case for a new model for scaling up treatment and prevention of HIV amongst Injecting Drug Users.

23 Jul 2010

Health bodies to discuss steps to further reduce mother to child HIV transmission

Transmission of HIV to children before or at birth has dropped dramatically around the country in the last decade since the advent of powerful new therapies. That certainly is true for Florida, where each year, fewer than 10 babies are born with the disease despite the fact that more than 600 HIV-positive women each year, on average, give birth.

23 Jul 2010

Study identifies infection mechanism of disease-causing microbes

A study published in the July 23 issue of Cell identifies the mechanism used by several types of common, virulent microbes to infect plants and cause devastating blights. Microbes using this infection mechanism include fungi that are currently causing wheat rust epidemics in Africa and Asia, and a class of parasitic algae, called oomycetes, that resulted in the Irish potato blight of the 19th Century. These microbes remain an agricultural scourge today.

23 Jul 2010

Pneumonia, diarrhea, and malaria cause death of 6 million of world's poorest children

A Johns Hopkins University scientist, whose team of researchers recently identified pneumonia, diarrhea, and malaria as the primary causes of death of 6 million of the world's poorest children, today called on leaders in donor and developing nations to take action to address the terrible death toll.

23 Jul 2010

Early HAART during TB treatment prolongs survival of untreated HIV-infected adults: CAMELIA study

A clinical trial in Cambodia has found it possible to prolong the survival of untreated HIV-infected adults with very weak immune systems and newly diagnosed tuberculosis (TB) by starting anti-HIV therapy two weeks after beginning TB treatment, rather than waiting eight weeks, as has been standard.

23 Jul 2010

NVHR releases statement on New York Times article 'Hope against Hepatitis C'

In response to today's New York Times article, "Hope against Hepatitis C," Andrew Muir, M.D., M.H.S., Director, Gastroenterology/Hepatology Research, Duke Clinical Research Institute and Steering Committee Member of the National Viral Hepatitis Roundtable (NVHR) released the following statement:

23 Jul 2010

Boehringer Ingelheim's VERxVE study of nevirapine meets primary endpoint

New data were presented today at the 18th International AIDS Conference from the VERxVE study that show an investigational, once-daily extended-release (400 mg QD) formulation of nevirapine was non-inferior to twice-daily immediate release Viramune® (nevirapine) tablets (200 mg BID), both in combination with Truvada® (tenofovir and emtricitabine) tablets in treatment-naive HIV-1 infected patients through 48 weeks.

23 Jul 2010

Corporation for National and Community Service awards National AIDS Fund $3.6 million SIF grant

The National AIDS Fund announced today it is one of 11 organizations to receive the first-ever Social Innovation Fund grants, an initiative administered by the Corporation for National and Community Service. The $3.6 million SIF grant will enable NAF to expand the scope of its Access to Care initiative in support of innovative public-private partnerships to improve individual health outcomes and strengthen local services systems, connecting economically and socially marginalized individuals living with HIV to high quality supportive services and health care.

23 Jul 2010

Sec. of State Clinton participates in ASEAN forum; ASEAN health ministers meet

Secretary of State Hillary Rodham Clinton arrived in Vietnam on Thursday to participate in the Association of Southeast Asian Nations (ASEAN) regional forum and to mark the 15th anniversary of the normalization of diplomatic relations between the U.S. and Vietnam, VOV News reports. According to the news service, this is Clinton's first visit to the country since she became secretary of state. During her trip, she will have meetings with Deputy Minister and Foreign Minister Pham Gia Khiem (7/22).

23 Jul 2010

National Jewish Health receives $31M NIH contract to study skin infections associated with atopic dermatitis

The National Institute of Allergy and Infections Disease has awarded a five-year $31 million contract to National Jewish Health, which is leading a consortium of academic medical centers seeking to better understand skin infections associated with atopic dermatitis. The researchers will focus on antibiotic-resistant staphylococcus aureus (MRSA) infections and widespread viral infections of the skin, both of which are more prevalent among atopic dermatitis patients.

23 Jul 2010

Independent DSMB recommends Inhibitex to complete FV-100 Phase II clinical trial for shingles

Inhibitex, Inc. today announced that the independent data safety monitoring board (DSMB) responsible for reviewing safety data from the Company's ongoing Phase II clinical trial of FV-100 met, as scheduled, after the Company had provided it with complete 30-day follow-up safety data on the third quartile (75%) of the patients that the Company plans to enroll in the trial. Based upon its review, the DSMB recommended that the trial continue to completion without modification.

23 Jul 2010

Schizophrenia patients likely to sustain medical injuries during non-psychiatric hospital stay

People with schizophrenia are more likely than others to sustain medical injuries during non-psychiatric hospital stays, a large national study finds.These findings confirm that medical and surgical hospitalizations are an at-risk time for this group, and a national problem, said lead study author Elizabeth Khaykin, at the Department of Mental Health at Bloomberg Johns Hopkins School of Public Health.

23 Jul 2010

Reusing syringes in anesthesia leads to viral transmission: Study

Hepatitis B virus and hepatitis C virus can be transmitted during intravenous administration of anesthesia, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association Institute. In this study, doctors found that anesthesia contamination - not endoscopy contamination - was the cause of infection.

23 Jul 2010

Researchers discover fundamental entry mechanism of fungal microbes into plant and human host cells

A research team led by scientists at the Virginia Bioinformatics Institute (VBI) at Virginia Tech has discovered a fundamental entry mechanism that allows dangerous fungal microbes to infect plants and cause disease. The discovery paves the way for the development of new intervention strategies to protect plant, and even some animal cells, from deadly fungal infections. The findings are published in the July 23 edition of the journal Cell.

23 Jul 2010

AIDS 2010 studies, releases: Criminalization, discrimination of high-risk groups; Test-and-treat; UNAIDS launches HIV prevention commission

The criminalization of men who have sex with men (MSM) and transgender people in Asia is holding back efforts to contain HIV/AIDS in the region, according to a report presented Wednesday by the U.N. Development Program (UNDP) and Asia Pacific Coalition on Male Sexual Health at the International AIDS Conference-AIDS 2010, VOA News reports. The report "linked the criminalization of homosexual behavior to an increase in the infection rate of HIV and AIDS in Asia," the news service writes (Dewan, 7/21).

23 Jul 2010

AIDS 2010: Halving HIV/TB co-infection deaths; Financial transaction tax discussed, and more

UNAIDS and the Stop TB Partnership joined together on Thursday at the International AIDS Conference-AIDS 2010 in Vienna, Austria, with the goal of preventing 200,000 deaths annually from HIV and tuberculosis co-infection, Agence France-Presse reports. TB is the number one killer of people living with HIV/AIDS (Ingham, 7/22).

23 Jul 2010

New HIV drug on the block

Johnson and Johnson’s experimental HIV drug rilpivirine or TMC278, a non-nucleoside reverse transcriptase inhibitor (NNRTI), is being developed for use in combination therapy for treating the human immunodeficiency virus (HIV) that causes AIDS. Two clinical trials with the drug has shown that although its effectiveness was same as the existing anti-HIV drugs, its side effects were fewer. On the flip side nearly twice as many patients failed to respond to treatment with the new drug.

22 Jul 2010

Tibotec reports Phase 3 trial results of TMC278 vs. EFV in treatment-naive HIV-1-infected adults

Tibotec Pharmaceuticals announced today results from two pivotal Phase 3, double-blind, randomized clinical trials comparing the efficacy, safety and tolerability of its investigational non-nucleoside reverse transcriptase inhibitor (NNRTI) TMC278 (rilpivirine) versus efavirenz (EFV), each administered once daily with a nucleoside/nucleotide background regimen in treatment-naive, HIV-1-infected adults.

22 Jul 2010

Achillion nominates ACH-2928 NS5A clinical candidate for treatment of HCV

Achillion Pharmaceuticals, Inc., a leader in the discovery and development of treatments for the most challenging infectious diseases, today announced the nomination of a lead clinical candidate in its fourth proprietary program against hepatitis C virus (HCV) infection. The candidate, ACH-2928, is an NS5A inhibitor that in preclinical studies has demonstrated excellent potency against HCV RNA replication, as well as good pharmacokinetic and safety profiles.

22 Jul 2010

Towards a cure: HIV reservoirs and strategies to control them

Can HIV infection ever be cured? The prospect of efficiently controlling HIV persistence in infected persons was the topic of a high-level, two-day meeting of researchers gathered here on the eve of AIDS 2010, the biennial international conference of HIV researchers, funders, policy-makers and advocates.

22 Jul 2010

Disease/Infection News

New model for scaling up treatment, prevention of HIV amongst IDUs

Health bodies to discuss steps to further reduce mother to child HIV transmission

Study identifies infection mechanism of disease-causing microbes

Pneumonia, diarrhea, and malaria cause death of 6 million of world's poorest children

Early HAART during TB treatment prolongs survival of untreated HIV-infected adults: CAMELIA study

NVHR releases statement on New York Times article 'Hope against Hepatitis C'

Boehringer Ingelheim's VERxVE study of nevirapine meets primary endpoint

Corporation for National and Community Service awards National AIDS Fund $3.6 million SIF grant

Sec. of State Clinton participates in ASEAN forum; ASEAN health ministers meet

National Jewish Health receives $31M NIH contract to study skin infections associated with atopic dermatitis

Independent DSMB recommends Inhibitex to complete FV-100 Phase II clinical trial for shingles

Schizophrenia patients likely to sustain medical injuries during non-psychiatric hospital stay

Reusing syringes in anesthesia leads to viral transmission: Study

Researchers discover fundamental entry mechanism of fungal microbes into plant and human host cells

AIDS 2010 studies, releases: Criminalization, discrimination of high-risk groups; Test-and-treat; UNAIDS launches HIV prevention commission

AIDS 2010: Halving HIV/TB co-infection deaths; Financial transaction tax discussed, and more

New HIV drug on the block

Tibotec reports Phase 3 trial results of TMC278 vs. EFV in treatment-naive HIV-1-infected adults

Achillion nominates ACH-2928 NS5A clinical candidate for treatment of HCV

Towards a cure: HIV reservoirs and strategies to control them

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

Latest News