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New drug shows promise in fighting Tuberculosis (TB)

Scientists from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have determined how a promising drug candidate attacks the bacterium that causes tuberculosis (TB). Published online this week in Proceedings of the National Academy of Sciences, the finding may help scientists optimize the drug candidate, PA-824, which targets Mycobacterium tuberculosis (M. tb).

28 Dec 2005

Childhood infections stunt growth and reduce life expectancy

Records from four European countries show that, on average, survivors of generations with rampant childhood infection - measured by cohort mortality rates at young ages - were shorter and died sooner than counterparts from generations with less childhood disease.

28 Dec 2005

Blacks more likely to die of curable lung cancer than whites

Even when they have equal access to specialized care, blacks with potentially curable lung cancer are about half as likely as whites to undergo surgery that could save their lives, according to a study by Dana-Farber Cancer Institute researchers.

28 Dec 2005

Blue-green algae shows promise as a natural weapon against Alzheimer's

A compound isolated from a cyanobacterium, a type of blue-green algae known as Nostoc, shows promise of becoming a natural drug candidate for fighting Alzheimer's and other neurodegenerative diseases, according to an in vitro study by researchers in Switzerland.

28 Dec 2005

Talks between Bulgaria, Libya delayed as emotions run high over HIV children fund

Five Bulgarian nurses and one Palestinian doctor, who had been sentenced to death by firing squad, following a conviction of infecting 426 children with HIV in a hospital, have had that conviction quashed and a new trial has been ordered by Libya's Supreme Court.

28 Dec 2005

China's new bird flu vaccine ready to go

According to the state media, China is about to begin mass-production of a new bird flu vaccine for poultry by the end of the month.

28 Dec 2005

Heart disease risk higher if a brother or sister has heart problems

According to a new report having a brother or sister with a cardiovascular disease poses a greater risk than having a parent with a history of the disease.

28 Dec 2005

Even lower blood sugar levels advocated to avoid heart disease

According to a researcher and diabetes expert, doctors with diabetic patients should be aiming for much lower levels of blood glucose than is currently suggested by the guidelines.

22 Dec 2005

Tamiflu may not be as effective as hoped against bird flu

The stockpiles of bird flu drug Tamiflu, accumulated by governments around the world as the first line of defense against a flu pandemic, may prove to be useless.

22 Dec 2005

Targeted cancer therapies: Another step forward

While it is clear that the treatment of cancer has already begun to undergo a paradigm shift with the inclusion of innovative targeted therapies into current regimens, it would be wrong to assume these products will entirely replace traditional chemotherapy as the standard treatment for cancer sufferers.

22 Dec 2005

Targeted cancer therapies: Another step forward

22 Dec 2005

Micro-gyroscopes could detect, monitor and provide therapy guidance on cancer

A vibrating disc no bigger than a speck of dust could help to diagnose and monitor common types of cancer and provide specialists with information about the most appropriate therapy.

22 Dec 2005

Early, aggressive treatment of type 1 diabetes reduced risk heart disease and stroke

Intensive and early treatment of type 1 diabetes substantially lowers the risk of cardiovascular ailments such as heart disease and stroke, a new multicenter study shows.

22 Dec 2005

Imatinib mesylate (Gleevec) may not be effective at treating kidney cancer

Mayo Clinic Cancer Center investigators report that imatinib mesylate (GleevecTM), the drug used to treat patients with gastrointestinal stromal cancers (GISTs), is not likely to be effective for patients with high grade renal cell carcinoma -- the most aggressive kidney cancer.

22 Dec 2005

Scientists discover how HIV infects healthy cells

Using sophisticated detection methods, researchers at the Saint Louis University Institute for Molecular Virology (IMV) have demonstrated the molecular mechanism by which the HIV virus infects, or integrates, healthy cells. The discovery could lead to new drug treatments for HIV.

22 Dec 2005

Discovery reveals how malaria infects humans

Researchers at the International Centre for Genetic Engineering and Biotechnology (ICGEB) in India and a unit of the European Molecular Biology Laboratory (EMBL) in France have made a key discovery about a molecule that helps the malaria parasite infect human cells.

22 Dec 2005