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Hybrid immunity from vaccination and Omicron BA.1 or BA.5 breakthrough infections exhibits cross-reactive efficacy against BA.2.75

Researchers recently measured the neutralizing antibody titers against the wild-type strain of SARS-CoV-2 and the SARS-CoV-2 Omicron subvariants in healthcare workers fully vaccinated with three doses of the Comirnaty vaccine who experienced breakthrough Omicron infections.

8 Nov 2022

Italian study examines the experiences of expectant mothers during the COVID-19 pandemic

Researchers from Italy performed a qualitative study on the lived experiences of women who were pregnant during the COVID-19 pandemic to understand the adverse physical and mental health outcomes associated with experiencing pregnancy and childbirth during the pandemic-enforced restrictions.

8 Nov 2022

Study identifies a potential pharmacological target for treating COVID-19-associated heart failure

Researchers at the University of Maryland School of Medicine's (UMSOM) Center for Precision Disease Modeling identified how a specific protein in SARS-CoV-2, the virus responsible for COVID-19, damages heart tissue. They then used a drug to reverse the toxic effects of that protein on the heart.

8 Nov 2022

Study: Fenofibrate not a useful strategy for decreasing COVID-19 severity

After showing promise in early laboratory research, the cholesterol-lowering drug fenofibrate had no significant effect on COVID-19 outcomes in a multicenter international randomized clinical trial led by Penn Medicine scientists.

8 Nov 2022

U.S. COVID-19 vaccine safety surveillance results for the over 65s

In a recent study posted to the medRxiv* server, researchers conducted near real-time safety monitoring in the United States (US) elderly population for 14 safety outcomes weekly following the coronavirus disease 2019 (COVID-19) vaccination

7 Nov 2022

Modeling predicts a declining trend in monkeypox cases globally and on a country-specific scale

In a recent study posted to the medRxiv* server, researchers at Georgia State University, USA, generated short-term forecasts of new monkeypox cases using an ensemble and subepidemic model.

7 Nov 2022

Rosuvastatin vastly superior to six common heart health supplements

Six widely used dietary supplements often advertised to promote heart health are actually ineffective at lowering cholesterol levels.

7 Nov 2022

COVID-19 amplifies damage to the central nervous system in Alzheimer's disease

In a recent study published in the journal Annals of Diagnostic Pathology, researchers in the United States evaluated the impact of coronavirus disease 2019 (COVID-19) on central nervous system (CNS) damage in Alzheimer's disease (AD).

7 Nov 2022

Study shows consistent efficacy of Paxlovid regardless of age, number of vaccinations, comorbidities

In a recent study posted to the medRxiv* preprint server, researchers in Canada evaluated nirmatrelvir and ritonavir (Paxlovid) effectiveness against severe coronavirus disease 2019 (COVID-19) during the dominance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC) and Omicron sub-VOCs in Canada.

7 Nov 2022

Vaccine confidence declined significantly since the start of the pandemic, study suggests

A new study suggests that, despite the success of the COVID-19 vaccination campaigns, vaccine confidence has declined significantly since the start of the pandemic.

7 Nov 2022

Paxlovid antiviral therapy reduces risk of long COVID

In a recent study posted to the medRxiv* server, researchers in Saint Louis, Missouri, examined whether nirmatrelvir treatment reduced the risk of long COVID, the disease encompassing the post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [PASC].

7 Nov 2022

Viral whole genome study in the United States identifies ORF-disrupting mutations in monkeypox virus

Researchers used whole genome sequencing to evaluate monkeypox virus samples from Washington and Ohio states in the United States and identified 25 samples with open reading frame (ORF)-disrupting mutations.

7 Nov 2022

SARS-CoV-2 activates NLRP3 inflammasome

Researchers assessed the role of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the NLR family pyrin domain containing 3 (NLRP3) inflammasome activation.

7 Nov 2022

Phylodynamic analysis of the monkeypox virus genome suggests low genetic variation and evolutionary rates

Researchers explored the genetic variability among the monkeypox virus genomes of Clade IIb lineage B.1 using a phylodynamic and genetic survey to confirm the epidemic cluster in the clade and understand the evolution of the virus.

7 Nov 2022

Multinational consensus to end COVID-19 pandemic

A new study recommended specific actions to end the coronavirus disease 2019 (COVID-19) pandemic.

7 Nov 2022

Findings from a multi-year initiative aimed at improving HIV health outcomes

The results of a multi-year initiative aimed at improving HIV health outcomes for Black men who have sex with men (MSM) are published in a new Supplement in the peer-reviewed journal AIDS Patient Care and STDs.

7 Nov 2022

Evaluating dual direct-acting antivirals against persistent COVID-19

Researchers assessed the efficiency of dual direct-acting antivirals in treating persistent coronavirus disease 2019 (COVID-19).

7 Nov 2022

Does the time of day patients receive their COVID-19 vaccinations influence their clinical benefit?

Researchers investigated whether the time of day at which COVID-19 patients receive their SARS-CoV-2 vaccinations influences the vaccine effectiveness.

7 Nov 2022

The transmission dynamics of the monkeypox outbreak in the UK

Researchers analyzed monkeypox virus transmission dynamics among United Kingdom residents.

7 Nov 2022

Llusern debuts Lodestar UTI molecular diagnostic platform at Medica 2022

UK diagnostics manufacturer, Llusern Scientific, will preview its Lodestar DX molecular platform at Medica 2022 in Dusseldorf (14-17 November).

From Llusern Scientific Ltd. 7 Nov 2022

Disease/Infection News

Hybrid immunity from vaccination and Omicron BA.1 or BA.5 breakthrough infections exhibits cross-reactive efficacy against BA.2.75

Italian study examines the experiences of expectant mothers during the COVID-19 pandemic

Study identifies a potential pharmacological target for treating COVID-19-associated heart failure

Study: Fenofibrate not a useful strategy for decreasing COVID-19 severity

U.S. COVID-19 vaccine safety surveillance results for the over 65s

Modeling predicts a declining trend in monkeypox cases globally and on a country-specific scale

Rosuvastatin vastly superior to six common heart health supplements

COVID-19 amplifies damage to the central nervous system in Alzheimer's disease

Study shows consistent efficacy of Paxlovid regardless of age, number of vaccinations, comorbidities

Vaccine confidence declined significantly since the start of the pandemic, study suggests

Paxlovid antiviral therapy reduces risk of long COVID

Viral whole genome study in the United States identifies ORF-disrupting mutations in monkeypox virus

SARS-CoV-2 activates NLRP3 inflammasome

Phylodynamic analysis of the monkeypox virus genome suggests low genetic variation and evolutionary rates

Multinational consensus to end COVID-19 pandemic

Findings from a multi-year initiative aimed at improving HIV health outcomes

Evaluating dual direct-acting antivirals against persistent COVID-19

Does the time of day patients receive their COVID-19 vaccinations influence their clinical benefit?

The transmission dynamics of the monkeypox outbreak in the UK

Llusern debuts Lodestar UTI molecular diagnostic platform at Medica 2022

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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