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Calluna Pharma successfully completes Phase 1 clinical study of CAL101, a first-in-class therapeutic for fibrotic and fibro-inflammatory indications

Calluna Pharma AS (Calluna), a clinical stage biotechnology company pioneering first-in-class antibodies to treat inflammatory and fibrotic diseases, today announced the completion of Phase 1 clinical study for CAL101, Calluna’s lead product candidate.

23 Oct 2024

Floor swabbing offers new insights for COVID-19 monitoring

COVID-19 is here to stay. As restrictions and human testing have waned, new research is tackling the challenge of how we can monitor, predict, and prevent cases and outbreaks of COVID-19, especially among vulnerable groups like hospitalized patients.

22 Oct 2024

FDA funding fuels research on turkey parasite and potential treatments

As scientists learn more about a deadly parasite's ability to move from host to host in turkey flocks, a long-standing theory is in question and opens the door to new preventative measures.

22 Oct 2024

New CDC report highlights disparities in flu hospitalization and vaccination

Black, Hispanic, and American Indian/Alaska Native (AI/AN) adults in the United States are more likely to be hospitalized with flu, as well as less likely to be vaccinated against flu, according to a new CDC Vital Signs report.

22 Oct 2024

INTEGRA Biosciences’ pipettes help progress small molecule inhibitors from discovery to clinical trials

RAPT Therapeutics in San Francisco, USA, relies on INTEGRA Biosciences’ pipettes to seamlessly accelerate the development of its candidate small molecule inhibitors for the treatment of inflammatory diseases and cancers.

From INTEGRA Biosciences 22 Oct 2024

New research uncovers how coronavirus evades immune defense

The novel coronavirus SARS-CoV-2 has an enzyme that can counteract a cell's innate defense mechanism against viruses, explaining why it is more infectious than the previous SARS and MERS-causing viruses.

22 Oct 2024

New single-chain mRNA vaccines offer enhanced immunity and protection against mpox

Study reveals single-chain mRNA vaccines confer 100% protection against lethal mpox challenge in mice, marking a significant advancement in vaccine technology.

22 Oct 2024

Diabetes drugs may reduce risk of opioid overdose and alcohol intoxication

Researchers examine the association between prescriptions of diabetes drugs and the incidence of alcohol intoxication and opioid overdose.

22 Oct 2024

Frequent ultra-processed food consumption raises mortality risks, especially in women

Ultra-processed food intake is linked to increased all-cause and cause-specific mortality, particularly in females, with metabolomic signatures highlighting the associated risks. This study provides critical evidence on the health dangers of UPFs.

22 Oct 2024

Affordability and supply remain critical to the success of long-lasting HIV drug

Affordability and mass distribution will be critical to the success of a long-lasting injectable HIV prevention drug that has proven highly effective in human trials, say global health specialists.

21 Oct 2024

Genetic variant identified as potential predictor for severe ulcerative colitis

The HLA-DRB1*01:03 genetic variant is associated with severe ulcerative colitis, significantly raising the risk of major surgeries and hospitalizations.

21 Oct 2024

Egypt achieves historic malaria-free certification

The World Health Organization (WHO) has certified Egypt as malaria-free, marking a significant public health milestone for a country with more than 100 million inhabitants.

21 Oct 2024

Sweden exceeds UNAIDS HIV goals but faces new challenges

Sweden has surpassed the UNAIDS 95-95-95 targets, with reduced HIV incidence and a steady increase in diagnosed and treated cases. However, challenges remain, especially among migrant populations and recent arrivals.

20 Oct 2024

Real world data highlights effectiveness of RSV vaccine

A multi-state study, published in The Lancet, is one of the first real world data analyses of the effectiveness of the RSV -- short for respiratory syncytial virus -- vaccine.

18 Oct 2024

Sweden becomes first country to meet global HIV targets

Sweden has reached the UNAIDS and WHO targets for the HIV epidemic, according to a study in Eurosurveillance by researchers at Karolinska Institutet and others.

18 Oct 2024

Exclusion of indigenous voices hinders HIV progress in Latin America

Indigenous communities in Latin America say they are being excluded from the global HIV/AIDS response, leaving them without access to life-saving medicines and prevention tools.

18 Oct 2024

The molecular underpinnings by which traumatic brain injury increases Alzheimer's disease risk

Findings indicate BAG3 modulation after traumatic brain injury may mitigate tau buildup and cognitive deficits, presenting a target for Alzheimer's prevention.

18 Oct 2024

Understanding cardiovascular risks in endometriosis patients

Endometriosis increases the risk of cardiovascular events.

18 Oct 2024

New consortium launched to combat Mpox outbreak in Africa

University College Dublin (UCD) is leading MpoxVax AFRIVAC, a new €1.3 million international consortium that aims to rapidly deploy technology and develop new knowledge to end the current Mpox outbreak in the Democratic Republic of Congo (DRC) and surrounding countries.

17 Oct 2024