Disease/Infection News

RSS

Glucosidase inhibitors hold promise as novel therapeutic agents against SARS-CoV-2

In a new study posted to the bioRxiv* preprint server, researchers from the United States report that two iminosugar glucosidase inhibitors have the ability to suppress the replication of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in tissue culture – at concentrations of at least 100 times lower than required for cytotoxic effects.

19 May 2021

How SARS-CoV-2 evolved from a bat-to a human-adapted virus

New research published on the preprint server bioRxiv* performed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genomic simulations to understand the evolutionary transition from a bat-adapted SARS-CoV-2 to a human-adapted virus.

19 May 2021

Study identifies mechanism behind SARS-CoV-2 fusion of host cells

The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is mediated by the fusion of the spike protein to nearby healthy cells. New research by German researchers sheds light on how this happens.

19 May 2021

Animal and insect invasions could shed light on COVID-19 transmission

Invasions by alien insect and animal species have much in common with outbreaks of infectious diseases and could tell us a great deal about how pandemics spread, according to a research paper published today.

19 May 2021

Latest round of REACT-1 finds SARS-CoV-2 prevalence has halved since previous round

Researchers in the UK say the latest round of the REal-time Assessment of Community Transmission-1 (REACT-1) study has found that the prevalence of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – has fallen by 50%, compared with the previous round conducted in March of this year (2021).

19 May 2021

Study investigates mental health consequences of COVID-19 geriatric care in nursing homes

No matter one's age, race, gender, socioeconomic status or political party, COVID-19 has impacted everyone at some level. That impact has been especially palpable for the approximately 1.3 million elderly Americans who reside in the country's 15,600 nursing homes.

19 May 2021

Pandemic protocols in workplace resulted in less "sickness presenteeism"

Employer COVID-19 safety measures influenced worker precautions even when they were not on the clock, according to a new study out of Washington State University.

19 May 2021

Researchers found disparities for COVID-19 testing and positivity rates in West Virginia

In studying COVID-19 testing and positivity rates in West Virginia between March and September 2020, West Virginia University researchers found disparities among Black residents and residents experiencing food insecurity.

19 May 2021

New study will help investigate innate immune responses to viral infections

Researchers from Boston University School of Medicine (BUSM) report the formation of human cells containing a green fluorescent protein or GFP (one of the most important proteins in biology and fluorescence imaging) genetically fused with two interferon stimulated genes (ISGs), namely Viperin and ISG15.

19 May 2021

Scientists provide a new approach to model infectious diseases

In the midst of a devastating global pandemic of wildlife origin and with future spillovers imminent as humans continue to come into closer contact with wildlife, infectious-disease models that consider the full ecological and anthropological contexts of disease transmission are critical to the health of all life.

19 May 2021

Researchers propose new way to treat chronic lung condition

Traditionally, an infection is thought to happen when microbes - bacteria, fungi, or viruses - enter and multiply in the body, and its severity is associated with how prevalent the microbes are in the body.

19 May 2021

People with venom allergies are more likely to have bone marrow disorder

Researchers at Michigan Medicine found that people with venom allergies are much more likely to suffer mastocytosis, a bone marrow disorder that causes higher risk of fatal reactions.

19 May 2021

Antibody response following SARS-CoV-2 mRNA vaccine is greater than natural infection

Researchers in the United States have provided the first evidence that messenger RNA (mRNA)-based vaccines against severe acute respiratory coronavirus 2 (SARS-CoV-2) induce a broader array of antibody subtypes against the viral spike protein than natural infection does.

19 May 2021

Methotrexate impairs immunogenicity of BNT162b2 SARS-CoV-2 vaccine in patients with immune-mediated inflammatory diseases

Researchers from Germany and the USA recently investigated the cellular and humoral immune responses of patients with IMIDs on immunomodulatory treatment to mRNA COVID-19 vaccines. The research is published on the medRxiv* preprint server.

19 May 2021

Despite sufficient information on COVID-19, Central PA residents worry about mixed messages

Residents of central Pennsylvania had the information they needed to slow the spread of COVID-19 early on in the pandemic, but were overwhelmed with worries about mixed messages and distrust of some sources, according to Penn State College of Medicine researchers.

19 May 2021

Despite socioeconomic status, racial and ethnic populations endure worse COVID-19 outcomes

A research team, led by the University of Minnesota Medical School, found that regardless of socioeconomic status, Twin Cities residents of underrepresented racial and ethnic backgrounds endure worse COVID-19 outcomes compared to people who are white.

18 May 2021

SARS-CoV-2 mRNA vaccine PTX-COVID19-B safe and highly immunogenic in preclinical study

COVID-19, the coronavirus disease of 2019, is one of the worst pandemics in human history. It emerged in December 2019 and is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Nearly 164 million SARS-CoV-2 infections and 3.4 million deaths have been reported globally since the beginning of the pandemic, which is still raging in many countries.

18 May 2021

Potent antibody with unique genetic signature and spike recognition mechanism neutralizes SARS-CoV-2

In a new study, researchers used an antibody discovery technology to identify a new potently neutralizing antibody with a unique mode of SARS-CoV-2 recognition. They reported their results on the bioRxiv preprint server.

18 May 2021

Robust T cell and humoral immune response to SARS-CoV-2 in patients with immunodeficiency

A study of immune-deficient adults and children has shown that patients who fail to respond positively to infections and vaccinations have robust humoral immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) structural proteins.

18 May 2021

SARS-CoV-2 B.1.1.420 and B.1.617.1 immune escape variants reported in France

Researchers discovered the first N440K variant and the new E484Q and L452R Indian variants isolated in France in a recent study. They presented the genetic mutations in the isolated genomes and the phylogenetic tree, including these strains among different SARS-CoV-2 clades. This work is posted on the bioRxiv preprint server.

18 May 2021

Disease/Infection News

Glucosidase inhibitors hold promise as novel therapeutic agents against SARS-CoV-2

How SARS-CoV-2 evolved from a bat-to a human-adapted virus

Study identifies mechanism behind SARS-CoV-2 fusion of host cells

Animal and insect invasions could shed light on COVID-19 transmission

Latest round of REACT-1 finds SARS-CoV-2 prevalence has halved since previous round

Study investigates mental health consequences of COVID-19 geriatric care in nursing homes

Pandemic protocols in workplace resulted in less "sickness presenteeism"

Researchers found disparities for COVID-19 testing and positivity rates in West Virginia

New study will help investigate innate immune responses to viral infections

Scientists provide a new approach to model infectious diseases

Researchers propose new way to treat chronic lung condition

People with venom allergies are more likely to have bone marrow disorder

Antibody response following SARS-CoV-2 mRNA vaccine is greater than natural infection

Methotrexate impairs immunogenicity of BNT162b2 SARS-CoV-2 vaccine in patients with immune-mediated inflammatory diseases

Despite sufficient information on COVID-19, Central PA residents worry about mixed messages

Despite socioeconomic status, racial and ethnic populations endure worse COVID-19 outcomes

SARS-CoV-2 mRNA vaccine PTX-COVID19-B safe and highly immunogenic in preclinical study

Potent antibody with unique genetic signature and spike recognition mechanism neutralizes SARS-CoV-2

Robust T cell and humoral immune response to SARS-CoV-2 in patients with immunodeficiency

SARS-CoV-2 B.1.1.420 and B.1.617.1 immune escape variants reported in France

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

Latest News