Disease/Infection News

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Illustrations by Nigerian artist kickstart debate on neglected tropical disease

Illustrations by a local artist in Nigeria are helping health workers and policy makers understand what it's really like to live with a neglected tropical disease (NTD).

5 Nov 2020

Researchers identify antibodies that prevent SARS-CoV-2 from infecting human cells

The ability of SARS-CoV-2 to infect cells depends on interactions between the viral spike protein and the human cell surface protein ACE2.

5 Nov 2020

Study reveals new mechanism underlying immune-cell activation

When antibody-producing immune cells encounter infectious pathogens for the first time, they engage a signal cascade to generate a massive activation signal within seconds.

5 Nov 2020

Study shows T cells can prevent Zika infection in mice

Where Aedes mosquitoes fly, Zika virus may not be far behind. Although the explosive 2015–2016 Zika epidemics in the Americas are behind us, Zika may re-emerge, and "in many countries, Zika may be spreading in silence," says Sujan Shresta, Ph.D., a professor at La Jolla Institute for Immunology (LJI).

5 Nov 2020

Green tea and some fruit juices inhibit SARS-CoV-2 in vitro

Green tea, chokeberry juice, and pomegranate juice killed flu and SARS-CoV-2 viruses when incubated with the viruses in vitro. Thus, oral rinsing using these might be effective in preventing COVID-19.

5 Nov 2020

Election rallies linked to an increase in COVID-19 hospitalizations

Researchers from Ben-Gurion University, Israel, Harvard Medical School, Boston, and Tel Aviv University, Israel, have studied the correlation between large gatherings and hospitalization risk due to COVID-19. Their study titled, “Association of Mass Gatherings and COVID-19 Hospitalization,” was published as a preprint on the medRxiv server.

4 Nov 2020

Providing the best psychiatric care within a safe environment during COVID-19 pandemic

The very heart of inpatient care for psychiatric patients is socialization, group therapy, shared meals, and a standard two people per room. Then COVID-19 hit with the accompanying public health warnings to isolate, socially distance, and wear masks.

4 Nov 2020

Novel approach for modeling spread of infectious disease

The rapid spread of SARS-CoV-2 across the world despite the early shutdown of borders and the cessation of international travel has sparked interest and given rise to changes in knowledge regarding the spread of infections.

4 Nov 2020

Case study reports prolonged infectious SARS-CoV-2 shedding from an asymptomatic leukemia patient

The majority of people infected with SARS-CoV-2 appear to actively shed infectious virus for about 8 days, but there is a wide range of variability from person to person.

4 Nov 2020

Ebola virus antibodies found in people prior to 2018 DRC outbreak

Scientists found antibodies to Ebola virus in people up to a year before the 2018 Ebola virus disease outbreak began in the Eastern Democratic Republic of Congo, or DRC.

4 Nov 2020

Zinc-embedded polyamide fabrics are effective in absorbing and inactivating SARS-CoV-2

An international team of scientists has recently demonstrated that zinc-embedded polyamine fibers can effectively absorb and inactivate human respiratory viruses, including influenza A virus and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Thus, a face mask or other personal protective equipment (PPE) made from this fiber is expected to provide better protection against viral transmission.

4 Nov 2020

Computational study reveals SARS-CoV-2 spike protein structural stability

Using dynamic contact maps and energy differences between different conformations of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein (or S-protein), an international team of researchers have recently published an article on the bioRxiv preprint server showing the different stable conformations of the spike protein.

4 Nov 2020

An analysis of genetic diversity of D614G mutation in SARS-CoV-2

A new study published in the preprint server bioRxiv in November 2020 reports that the effect of the mutation is minimal, in terms of pathogenicity or altered response to neutralizing antibodies elicited against the native virus strain.

4 Nov 2020

D614G mutation enhances stability of SARS-CoV-2 spike protein

A new study, published on the preprint server bioRxiv in November 2020 by researchers at the Indian Institute of Science, has explored this issue further. The researchers have found that this mutation is associated with structural and energetic changes that cause this spike variant to become more available during infection, thus rendering the associated strain more infective.

4 Nov 2020

UC researcher recommends screening teen emergency room patients for STIs

A University of Cincinnati researcher is recommending pediatric hospital emergency rooms consider screening for sexually transmitted infections (STI) teenage and young adult patients who visit for other acute care issues.

4 Nov 2020

Ozone water found to rapidly inactivate SARS-Cov-2

As the coronavirus disease 19 (COVID-19) pandemic appears here to stay, a new study published on the preprint server bioRxiv* in November 2020 reports an effective and rapid inactivation tactic for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); namely, through the use of ozone water.

4 Nov 2020

People treated with statins have 22% to 25% lower risk of dying from COVID-19

Coronavirus has infected more than 40 million people around the world and has caused more than a million deaths in less than a year.

4 Nov 2020

RNA-binding proteins may suppress antiviral defenses against SARS-CoV-2

Conducted by researchers in South Korea at the Institute for Basic Science and the International Vaccine Institute, a new study published on the preprint server bioRxiv in November 2020 describes the many host proteins that bind with the ribonucleic acid (RNA) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and regulate the replication of the virus.

4 Nov 2020

Texas A&M study identifies four significant predictors of COVID-19 cases

In March 2020, New York City, an icon of America, was unfortunately named an early epicenter of the novel coronavirus. Now seven months later, America faces a new surge in coronavirus cases and researchers at Texas A&M University hope to provide information and context to help with the battle ahead.

4 Nov 2020

Study shows brilacidin strongly inhibits SARS-CoV-2 in laboratory cell lines

A recent study by US researchers reveals that brilacidin, a small synthetic molecule with peptide-like properties, exerts potent in vitro antiviral activity against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – both as a standalone treatment and in combination with FDA-approved remdesivir. The study is currently available on the bioRxiv preprint server.

4 Nov 2020