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3D printed nanoparticle biosensing platform detects SARS-CoV-2 antibodies within seconds

Pandemics caused by novel infectious agents like the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Zika, or Ebola virus seriously impact human health and lives while also overwhelming health care systems all over the world. Early detection and diagnosis allow isolation of the infected patients and contact tracing, which can mitigate the spread of the virus and save lives, especially when a significant number of the patients are asymptomatic.

14 Sep 2020

Central nervous system immune responses to COVID-19

A recent study published on the preprint server bioRxiv by scientists from Yale School of Medicine, University of California, Yale School of Public Health, Yale University, and Howard Hughes Medical Institute examined the impact of SARS-CoV-2 infection on the central nervous system.

14 Sep 2020

NIH and FDA examine serious side effect that surfaced in COVID vaccine trial

The Food and Drug Administration is weighing whether to follow British regulators in resuming a coronavirus vaccine trial that was halted when a participant suffered spinal cord damage, even as the National Institutes of Health has launched an investigation of the case.

14 Sep 2020

Georgetown experts release report on pandemic preparedness and COVID-19 lessons

In a new report commissioned by the Global Preparedness Monitoring Board (GPMB), Georgetown global health experts say the success of any effort to redress pandemic preparedness failures demonstrated by COVID-19 requires a re-centering of governance that would include greater accountability, transparency, equity, participation and the rule of law.

14 Sep 2020

Smoke from wildfires may increase COVID-19 risk

The smoke the firefighters are breathing is heightening their risk of contracting the new coronavirus, with potentially life-threatening effects. Further, fighting the huge fires may make infection control measures such as hand washing and social distancing, challenging to perform.

14 Sep 2020

Oxford University and AstraZeneca resume COVID-19 vaccine trial

More than a hundred candidate vaccine trials against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes the coronavirus disease (COVID-19), are underway. About 35 are now undergoing clinical evaluation, and of these, nine are in the final phase of human trials, including the vaccine developed by Oxford University and the biopharmaceutical firm, AstraZeneca.

14 Sep 2020

Researchers find coping techniques linked with positive mental health during COVID-19

The early days of the COVID-19 pandemic contributed to negative mental health effects for many in the U.S., according to new Penn State research. But the researchers also found that some coping techniques -- like wearing masks and focusing on self-care -- were linked with positive mental health.

14 Sep 2020

Circadian rhythm affects SARS-CoV-2 infection and host immune response

In an interesting bioRxiv preprint paper, French researchers show that the time day can affect infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as well as guide subsequent host immune response – implying that circadian rhythm may well be a novel target for managing viral progression.

14 Sep 2020

Earlier treatment with steroids reduces adverse outcomes in patients with septic shock

Some critically ill patients with septic shock need medications called vasopressors to correct dangerously low blood pressure.

14 Sep 2020

Keto diet could be beneficial for elderly COVID-19 patients

A recent study by researchers at Yale School of Medicine, New York University Langone Health and Washington University School of Medicine, claims that the ketogenic diet (high fat, low carbohydrate diet) is capable of mitigating clinical outcomes of coronavirus disease 2019 (COVID-19) in elderly people by improving immune-metabolic functions and reducing inflammation. The study is currently available on the bioRxiv* preprint server.

14 Sep 2020

Children's Hospital Los Angeles is U.S. site for new study of SARS-CoV-2 spread within households

One of the mysteries about severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19, is how it is spread within households, including why some family members develop the viral infection and others do not.

14 Sep 2020

Computational models screen for coronaviruses likely to infect humans

The researchers from Rochester Institute of Technology and the Hauptmann-Woodward Medical Research Institute produced models of the receptor-binding domain (RBD) found on outbreak strains of betacoronaviruses and its interaction with the host cell receptor angiotensin-converting enzyme 2 (ACE2).

14 Sep 2020

Toyonaka Municipal Hospital reports successful control of COVID-19

Researchers at Toyonaka Municipal Hospital in Japan have shown that the rate of subclinical infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among staff at the hospital is no higher than among the general population in the same area.

14 Sep 2020

Sticky DNA webs may cause tissue damage associated with severe COVID-19 infections

Sticky webs of DNA released from immune cells known as neutrophils may cause much of the tissue damage associated with severe COVID-19 infections, according to two new studies published September 14 in the Journal of Experimental Medicine.

14 Sep 2020

Are children more likely to be SARS-CoV-2 asymptomatic than adults?

he frequency of children carrying asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been suggested to be higher than among adults. It is also suggested that asymptomatic children enhance viral spread. A new study published in the journal JAMA Pediatrics in September 2020 explores the truth of this common belief.

14 Sep 2020

Should a COVID-19 vaccine be mandatory for children?

As the search for a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine continues, with some candidate vaccines nearing the completion Phase III clinical trials, a trio of experts weighs in with some sound reasoning as to whether any future vaccine should be considered mandatory for children. The viewpoint article is published in the journal JAMA Pediatrics in September 2020.

14 Sep 2020

Researchers identify microRNA molecules that could repress the replication of human coronaviruses

HSE University researchers have found microRNA molecules that are potentially capable of repressing the replication of human coronaviruses, including SARS-CoV-2.

14 Sep 2020

Efforts to control COVID-19 could create a health time bomb in slum communities

Efforts to stem the impact of COVID-19 in low to middle income countries could be creating a health time bomb in their slum communities by deepening existing inequalities, according to an international team of health researchers led by the University of Warwick.

14 Sep 2020

New poll highlights feelings of loneliness and isolation among older adults during COVID-19

Staying close to home and avoiding crowded places can help older adults reduce their risk of COVID-19. But a new national poll suggests it comes with a cost, especially for those with health challenges.

14 Sep 2020

Sleep apnea patients could be at increased risk of adverse outcomes from COVID-19

People who have been diagnosed with obstructive sleep apnoea could be at increased risk of adverse outcomes from COVID-19 according to a new study from the University of Warwick.

14 Sep 2020

Disease/Infection News

3D printed nanoparticle biosensing platform detects SARS-CoV-2 antibodies within seconds

Central nervous system immune responses to COVID-19

NIH and FDA examine serious side effect that surfaced in COVID vaccine trial

Georgetown experts release report on pandemic preparedness and COVID-19 lessons

Smoke from wildfires may increase COVID-19 risk

Oxford University and AstraZeneca resume COVID-19 vaccine trial

Researchers find coping techniques linked with positive mental health during COVID-19

Circadian rhythm affects SARS-CoV-2 infection and host immune response

Earlier treatment with steroids reduces adverse outcomes in patients with septic shock

Keto diet could be beneficial for elderly COVID-19 patients

Children's Hospital Los Angeles is U.S. site for new study of SARS-CoV-2 spread within households

Computational models screen for coronaviruses likely to infect humans

Toyonaka Municipal Hospital reports successful control of COVID-19

Sticky DNA webs may cause tissue damage associated with severe COVID-19 infections

Are children more likely to be SARS-CoV-2 asymptomatic than adults?

Should a COVID-19 vaccine be mandatory for children?

Researchers identify microRNA molecules that could repress the replication of human coronaviruses

Efforts to control COVID-19 could create a health time bomb in slum communities

New poll highlights feelings of loneliness and isolation among older adults during COVID-19

Sleep apnea patients could be at increased risk of adverse outcomes from COVID-19

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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