Drug Discovery & Pharmaceuticals

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Repurposing or improving drugs for spinocerebellar ataxia type 5

A team of researchers has developed a new method to screen FDA-approved drugs to determine if they could be repurposed or improved to help patients with a rare, debilitating disease of the nervous system.

16 Feb 2023

Inventia Life Science collaborates with MSD to develop 3D advanced cell models for neurodegenerative disease drug discovery

Inventia Life Science, a world leader in advanced cell models for biomedical research and drug discovery, today announced a collaboration with MSD (tradename of Merck & Co., Inc., Rahway, N.J., USA) using Inventia’s RASTRUM™ 3D cell culture platform.

From Inventia Life Science 16 Feb 2023

Study could lead to a safe, on-demand and reversible oral contraceptive for men

In a mouse study, researchers funded by the National Institutes of Health have identified a potential non-hormonal contraceptive that men could take shortly before sexual activity and have fertility restored the next day.

14 Feb 2023

New analytical platform quantifies the structure of mRNA-based medicines

Researchers from Tokyo Metropolitan University and RIKEN CSRS have developed a new analytical platform based on liquid chromatography, mass spectrometry and software analysis that quantifies the structure of messenger RNA (mRNA) based medicines.

13 Feb 2023

Active compound from edible mushrooms boosts nerve growth and enhances memory

Researchers from The University of Queensland have discovered the active compound from an edible mushroom that boosts nerve growth and enhances memory.

10 Feb 2023

Researchers propose a pre-assembly strategy for efficient degradation of antibiotics

Recently, a research team led by Prof. KONG Lingtao from Institute of Solid State Research, Hefei Institutes of Physical Science of Chinese Academy of Sciences proposed a pre-assembly strategy to anchor single atoms on carbon nitride nanosheets.

9 Feb 2023

Researchers discover small molecules that can lock SARS-CoV-2 spike proteins

The infamous spike proteins on the surface of SARS-CoV-2 help it bind to and enter human cells. Because of their important role in spreading infection, these spike proteins are one of the main targets for COVID-19 vaccines and treatments.

9 Feb 2023

Researchers develop a new method to design peptide antibiotics

Hokkaido University researchers have developed a novel method to design and develop peptide antibiotics in large numbers, which will prove critical to controlling antibiotic resistance.

7 Feb 2023

Mucoactive drugs block SARS-CoV-2 infection

Researchers evaluate the effects of mucociliary active molecules on SARS-CoV-2 infection in vitro.

7 Feb 2023

AAHI awarded a $9.9 million project to develop prototype intranasal bivalent influenza RNA vaccine candidate

The Access to Advanced Health Institute announced today that it has been awarded a project agreement worth up to $9.9 million through the Medical CBRN Defense Consortium Other Transaction Authority to develop a prototype intranasal bivalent influenza RNA vaccine candidate based on AAHI's self-amplifying RNA (saRNA) platform that targets both pandemic A(H5N1) and A(H7N9) influenza virus pathogens.

6 Feb 2023

New method can control the growth of a substance known to cause kidney stones in dolphins

In the body, crystals – made of things such as calcium or a collection of urine – form masses that can cause pain and serious health conditions.

5 Feb 2023

Oncodesign Services looks to the future

As Oncodesign evolves into Oncodesign Services and begins its journey as an independent business, CEO Fabrice Viviani explains his hopes and plans for the company’s future.

From Oncodesign Services 3 Feb 2023

ERES IV acquires a majority stake in Oncodesign Services

Oncodesign Services, a leading Contract Research Organization (CRO) specializing in drug discovery and preclinical services in oncology and immuno-inflammation, and Elyan Partners announce the completion of the acquisition of a majority stake in Oncodesign Services by ERES IV, representing 61.58% of its share capital, from its main shareholders, including Mr. Philippe Genne, Founder of Oncodesign Services, as well as certain key shareholders and several managers and minority shareholders, following the entry into exclusive negotiations on June 30, 2022.

From Oncodesign Services 3 Feb 2023

UC Davis launches new institute to advance basic knowledge of psychedelics and neurotherapeutics

The University of California, Davis has launched the Institute for Psychedelics and Neurotherapeutics to advance basic knowledge about the mechanisms of psychedelics and translate it into safe and effective treatments for diseases such as depression, post-traumatic stress disorder, addiction, Alzheimer's disease and Parkinson's disease, among others.

2 Feb 2023

MD Anderson and Federation Bio collaborate to design and manufacture a synthetic microbial consortium

The University of Texas MD Anderson Cancer Center and Federation Bio today announced a strategic collaboration to design and manufacture a complex, synthetic microbial consortium with the goal of expanding the number of cancer patients who respond to immunotherapy.

1 Feb 2023

Researchers develop AI-based strategy for discovering high-affinity antibody drugs

Scientists at University of California San Diego School of Medicine have developed an artificial intelligence (AI)-based strategy for discovering high-affinity antibody drugs.

30 Jan 2023

New candidate molecule could become an effective non-hormonal male contraceptive

Despite birth control existing for decades, almost none of the options specifically target sperm cells. Researchers are now developing approaches that target testosterone or otherwise interrupt the sperm's ability to fertilize an egg, yet these may not work for everyone.

30 Jan 2023

Machine learning identifies drugs that could be repurposed to help people quit smoking cigarettes

Medications like dextromethorphan, used to treat coughs caused by cold and flu, could potentially be repurposed to help people quit smoking cigarettes, according to a study by Penn State College of Medicine and University of Minnesota researchers.

30 Jan 2023

$1 million grant will help University of Utah chemists to speed up the drug development process

Michael Grünwald, Ryan Looper and Rodrigo Noriega, of the University of Utah Department of Chemistry, received a $1 million grant from the W.M. Keck Foundation funding studies of currently unpredictable aspects of the process of crystallization.

30 Jan 2023

Novel class of sulfonamides to block malaria transmission

Malaria is a devastating disease, with 247 million cases and 619,000 deaths reported in 2021 alone. Malaria causes fever and a flu-like illness that occurs when people are infected with the parasite Plasmodium falciparum, which is spread by mosquitoes.

30 Jan 2023

Drug Discovery & Pharmaceuticals

Repurposing or improving drugs for spinocerebellar ataxia type 5

Inventia Life Science collaborates with MSD to develop 3D advanced cell models for neurodegenerative disease drug discovery

Study could lead to a safe, on-demand and reversible oral contraceptive for men

New analytical platform quantifies the structure of mRNA-based medicines

Active compound from edible mushrooms boosts nerve growth and enhances memory

Researchers propose a pre-assembly strategy for efficient degradation of antibiotics

Researchers discover small molecules that can lock SARS-CoV-2 spike proteins

Researchers develop a new method to design peptide antibiotics

Mucoactive drugs block SARS-CoV-2 infection

AAHI awarded a $9.9 million project to develop prototype intranasal bivalent influenza RNA vaccine candidate

New method can control the growth of a substance known to cause kidney stones in dolphins

Oncodesign Services looks to the future

ERES IV acquires a majority stake in Oncodesign Services

UC Davis launches new institute to advance basic knowledge of psychedelics and neurotherapeutics

MD Anderson and Federation Bio collaborate to design and manufacture a synthetic microbial consortium

Researchers develop AI-based strategy for discovering high-affinity antibody drugs

New candidate molecule could become an effective non-hormonal male contraceptive

Machine learning identifies drugs that could be repurposed to help people quit smoking cigarettes

$1 million grant will help University of Utah chemists to speed up the drug development process

Novel class of sulfonamides to block malaria transmission

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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