Drug Discovery & Pharmaceuticals

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New genetically encoded sensor helps detect drugs of abuse

A genetically encoded sensor to detect hallucinogenic compounds has been developed by researchers at the University of California, Davis. Named psychLight, the sensor could be used in discovering new treatments for mental illness, in neuroscience research and to detect drugs of abuse. The work is published April 28 in the journal Cell.

29 Apr 2021

New compound could alleviate neurological symptoms of CHARGE syndrome

CHARGE syndrome is a rare genetic disorder affecting about 1 in 10,000 newborns. It can lead to neurological and behavioural disorders for which no treatment is currently available.

28 Apr 2021

Cholestenone could be a new antibacterial drug against H. pylori

Helicobacter pylori (H. pylori), a gram-negative pathogen that has infected half of the world's population is a Group I carcinogen according to the WHO. H. pylori resides in the gastric mucosa causing gastritis, ulcers, gastric cancers and malignant lymphoma of the stomach.

27 Apr 2021

Study may provide a basis for oral insulin development using DNP peptides

Researchers from Kumamoto University, Japan have found that DNP peptide, a small intestine-permeable cyclic peptide originally used as an insulin additive to improve absorption into the small intestinal, lowers blood glucose levels in mice.

26 Apr 2021

Study characterizes anti-inflammatory effect of strawberry geranium on the skin

Strawberry geranium (Saxifraga stolonifera) has been used in Japan as a herbal medicine to treat wounds and swelling, and continues to be an ingredient in food and cosmetics.

23 Apr 2021

Researchers develop a method of fabrication for biodegradable polymer microcapsules

An international team led by a Skoltech researcher has developed a method of fabrication for biodegradable polymer microcapsules, made more efficient by turning to an unusual source of inspiration - traditional Russian dumpling, or pelmeni, making.

23 Apr 2021

Drug-discovery collaboration finds potential new antimalarial drug candidates

Potential new antimalarial drug candidates are being developed through an extended drug-discovery collaboration between Australian medical research institute WEHI and Janssen Pharmaceutica NV. The collaboration was facilitated by Johnson & Johnson Innovation.

22 Apr 2021

Collaborative research could expedite or eliminate the need to manually adjust bioproduction process

Much of common pharmaceutical development today is the product of laborious cycles of tweaking and optimization.

21 Apr 2021

Argonne's Advanced Photon Source guided the development of new COVID-19 vaccine now in trials

Human clinical trials have begun on a new vaccine candidate that may protect against not only SARS-CoV-2, the virus that causes COVID-19, but against at least two of the variants emerging around the world.

21 Apr 2021

Asymmetric technique to synthesize aziridines in the presence of newly developed catalysts

Unless you've studied chemistry in college, it's unlikely you've come across the name aziridine. An organic compound with the molecular formula, C2H4NH, aziridines are well-known among medicinal chemists, who make use of the compound to prepare pharmaceutical drugs such as Mitomycin C, a chemotherapeutic agent known for its anti-tumor activity.

20 Apr 2021

Rare compound found in a shrub could help fight previously 'undruggable' cancer protein

A chemist from Purdue University has found a way to synthesize a compound to fight a previously "undruggable" cancer protein with benefits across a myriad of cancer types.

20 Apr 2021

Bristol-based new biotech company is developing ground-breaking treatments for Covid-19

A team of top scientists from the University of Bristol have announced the formation of a new biotech company that is developing ground-breaking and newly patented potential treatments for Coronavirus.

16 Apr 2021

New machine learning method for designing more effective antibody drugs

Antibodies are not only produced by our immune cells to fight viruses and other pathogens in the body. For a few decades now, medicine has also been using antibodies produced by biotechnology as drugs.

15 Apr 2021

Linkam FDCS196 stage used in research to develop a novel transdermal delivery system for risperidone

The first study of its kind reports on the enhancement of skin permeability of risperidone (RIS) using eutectic systems.

From Linkam Scientific Instruments 14 Apr 2021

Researchers find a way to fine-tune the molecular assembly line that creates antibiotics

Researchers from North Carolina State University have found a way to fine-tune the molecular assembly line that creates antibiotics via engineered biosynthesis.

13 Apr 2021

Natural treatment based on flour made from mealworms can help prevent Type II diabetes mellitus

Scientists from the Bioreactors Research Group of the University of Granada have demonstrated that a natural treatment based on flour made from the insect Tenebrio molitor (more commonly known as the mealworm) can help prevent Type II diabetes mellitus.

13 Apr 2021

MagnaPharm project opens up new possibilities in drug production

Polymorphs are crystalline materials that have the same chemical composition but different molecular packing. For example, diamond and graphite are both made from crystalline forms of carbon, but their physical and chemical properties vary drastically.

13 Apr 2021

BGU researchers identify probiotic yogurt-based drug candidates

Researchers at Ben-Gurion University of the Negev (BGU) have for the first time identified new drug candidates based on molecules isolated from probiotic Kefir yogurt for combating pathogenic bacteria and treating various inflammatory conditions, including inflammatory bowel disease (IBD) and COVID-19 related cytokine storms.

12 Apr 2021

Researchers use genetics to identify potential drugs for early management of COVID-19

A new study using human genetics suggests researchers should prioritize clinical trials of drugs that target two proteins to manage COVID-19 in its early stages.

9 Apr 2021

Toward a transformative therapy for sickle cell patients

For the millions of people worldwide who have sickle cell disease, there are only a few treatment options, which include risky bone marrow transplants, gene therapy or other treatments that address a subset of symptoms.

9 Apr 2021

Drug Discovery & Pharmaceuticals

New genetically encoded sensor helps detect drugs of abuse

New compound could alleviate neurological symptoms of CHARGE syndrome

Cholestenone could be a new antibacterial drug against H. pylori

Study may provide a basis for oral insulin development using DNP peptides

Study characterizes anti-inflammatory effect of strawberry geranium on the skin

Researchers develop a method of fabrication for biodegradable polymer microcapsules

Drug-discovery collaboration finds potential new antimalarial drug candidates

Collaborative research could expedite or eliminate the need to manually adjust bioproduction process

Argonne's Advanced Photon Source guided the development of new COVID-19 vaccine now in trials

Asymmetric technique to synthesize aziridines in the presence of newly developed catalysts

Rare compound found in a shrub could help fight previously 'undruggable' cancer protein

Bristol-based new biotech company is developing ground-breaking treatments for Covid-19

New machine learning method for designing more effective antibody drugs

Linkam FDCS196 stage used in research to develop a novel transdermal delivery system for risperidone

Researchers find a way to fine-tune the molecular assembly line that creates antibiotics

Natural treatment based on flour made from mealworms can help prevent Type II diabetes mellitus

MagnaPharm project opens up new possibilities in drug production

BGU researchers identify probiotic yogurt-based drug candidates

Researchers use genetics to identify potential drugs for early management of COVID-19

Toward a transformative therapy for sickle cell patients

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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