Drug Discovery & Pharmaceuticals

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RUDN University scientists synthesize new range of cytotoxic substances

Scientists from RUDN University have synthesized a number of new cytotoxic substances - the ones that can damage cells. In the future the results of the study can be used in cancer therapy.

13 Oct 2017

New generation of drugs targets cancer cells’ vulnerability with broken genes

In recent years, new cancer treatments have brought hope to people who once had limited options. But for others, the wait for an effective drug continues.

12 Oct 2017

Human minibrains expose psychedelic drug effects, study reveals

A Brazilian study has detected variations in signaling pathways that are associated with neurodegeneration, inflammation, and neural plasticity stimulated by a compound from the dimethyltryptamine family known as 5-MeO-DMT.

10 Oct 2017

New webinar highlights importance of data integrity in GxP-regulated laboratories

As regulators continue to tighten their inspection approaches, it is critical for managers and scientists in regulated laboratories to understand the key issues surrounding data integrity and be able to demonstrate compliance.

6 Oct 2017

CGT Catapult’s iPSC line licensed to Universal Cells for creating universal donor cell line

The Cell and Gene Therapy Catapult today announced a non-exclusive licensing agreement to provide its clinical-grade induced Pluripotent Stem Cell line to Seattle based Universal Cells.

6 Oct 2017

Powerful new approach could aid design of better drugs with fewer side-effects

A powerful new way of analyzing how drugs interact with molecules in the body could aid the design of better treatments with fewer side-effects.

5 Oct 2017

Scientists manipulate living cells to produce fluorinated bioplastics

Natural organic compounds that contain fluorine are rare because living organisms—with a few exceptions—do not produce them.

4 Oct 2017

Researchers produce fluorinated molecules in living cells

Natural organic compounds that contain fluorine are rare because living organisms—with a few exceptions—do not produce them. American scientists have now genetically engineered a microbial host for organofluorine metabolism, allowing it to produce a fluoridated intermediate known as a diketide.

30 Sep 2017

University of Hawaii researcher receives $6.3 million grant for trivalent Ebola vaccine development

University of Hawaii vaccine researcher Axel Lehrer, PhD, has received a nearly $6.3 million grant to test whether the Ebola vaccine formula he has developed will protect against two additional viruses in the same family.

28 Sep 2017

Deep Genomics receives $13 million investment to create new class of genetic drugs

Deep Genomics, the AI driven genetic medicine company, received a USD $13 million equity investment led by Khosla Ventures, one of the top venture capital firms. They are accompanied by early stage investment firm True Ventures.

28 Sep 2017

High-speed method generates mini-protein binders with potential to become new class of drugs

Scientists have created a high-speed method to generate thousands of different, small, stable proteins from scratch that can be custom-designed to bind to specific therapeutic targets.

27 Sep 2017

Understanding molecular mechanisms and metabolic pathways of yeast for drug discovery

My research uses budding yeast as a tool for synthetic biology, and also in chemical and functional genomic applications. We are interested in understanding molecular mechanisms and metabolic pathways of yeast for drug discovery.

From Tecan 27 Sep 2017

SBP researcher awarded $10.8 million grant to pursue development of new drug for substance abuse

Sanford Burnham Prebys Medical Discovery Institute is pleased to announce the National Institute on Drug Abuse at the National Institutes of Health has awarded Nicholas Cosford, Ph.D., a three-year, $10.8 million grant to pursue the preclinical development of a new class of medicine to treat substance use disorders.

26 Sep 2017

Researchers use multi-modal integrated approach to develop potential anti-Chagas therapies

Chagas disease is a potentially life-threatening illness caused by the parasite, Trypanosoma cruzi, and is transmitted to humans through triatomine blood-sucking bugs that are commonly referred to as "kissing bugs" or "vampire bugs".

26 Sep 2017

Advanced technique could pave way for cascade of new steroidal therapeutics

Researchers at Dartmouth College have developed a technique to produce synthetic steroids that could pave the way for a cascade of new drug discoveries. The process, published in the journal Nature Chemistry, facilitates access to rare, mirror-image isomers of naturally occurring steroid structures.

26 Sep 2017

One-fourth of cancer patients use cannabis, study reveals

New research conducted in a cancer center in a state that had legalized the use of recreational and medicinal cannabis shown that about one-fourth of surveyed cancer patients used cannabis in the previous year, mostly for psychological and physical symptoms. The study also indicated that legalization increased the likelihood of a rise of cannabis use among cancer patients.

25 Sep 2017

New collaboration could lead to novel drugs that address unmet medical needs

Southern Research and the University of Tennessee Health Science Center have formed a partnership to advance promising research that could lead to new drugs that address unmet medical needs.

20 Sep 2017

LSUHealthNO to examine effectiveness of novel drug designed for heart muscle regeneration

In collaboration with Novo Biosciences, Inc., LSU Health New Orleans Cardiovascular Center of Excellence will receive more $500,000 over two years to study the effectiveness of a novel drug designed to stimulate the regeneration of heart muscle and prevent the formation or scar tissue following a heart attack.

15 Sep 2017

Porvair Sciences provide optimised microplate products for drug discovery scientists

Porvair Sciences offers a range of application optimised microplates and high-performance microplate equipment designed to enable drug discovery scientists to optimise sample preparation and improve productivity.

From Porvair Sciences Limited 15 Sep 2017

Pharmaceutical compound from leaves of coralberry may help combat asthma

The coralberry could offer new hope for asthmatics: researchers at the University of Bonn have extracted a new kind of active pharmaceutical ingredient from its leaves to combat this widespread respiratory disease. In mice, it almost completely inhibits the characteristic contraction of the airways.

14 Sep 2017

Drug Discovery & Pharmaceuticals

RUDN University scientists synthesize new range of cytotoxic substances

New generation of drugs targets cancer cells’ vulnerability with broken genes

Human minibrains expose psychedelic drug effects, study reveals

New webinar highlights importance of data integrity in GxP-regulated laboratories

CGT Catapult’s iPSC line licensed to Universal Cells for creating universal donor cell line

Powerful new approach could aid design of better drugs with fewer side-effects

Scientists manipulate living cells to produce fluorinated bioplastics

Researchers produce fluorinated molecules in living cells

University of Hawaii researcher receives $6.3 million grant for trivalent Ebola vaccine development

Deep Genomics receives $13 million investment to create new class of genetic drugs

High-speed method generates mini-protein binders with potential to become new class of drugs

Understanding molecular mechanisms and metabolic pathways of yeast for drug discovery

SBP researcher awarded $10.8 million grant to pursue development of new drug for substance abuse

Researchers use multi-modal integrated approach to develop potential anti-Chagas therapies

Advanced technique could pave way for cascade of new steroidal therapeutics

One-fourth of cancer patients use cannabis, study reveals

New collaboration could lead to novel drugs that address unmet medical needs

LSUHealthNO to examine effectiveness of novel drug designed for heart muscle regeneration

Porvair Sciences provide optimised microplate products for drug discovery scientists

Pharmaceutical compound from leaves of coralberry may help combat asthma

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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