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Treatment found to be safe, efficacious in improving insomnia and night sweats among midlife women

Hot flashes and night sweats are a common cause of insomnia among peri- and postmenopausal women. Hot flashes, night sweats and insomnia are all linked to reduced quality of life and distress.

17 Feb 2022

UC joins nationwide trial to evaluate efficacy of repurposed drugs for mild-to-moderate COVID-19

The University of Cincinnati is joining a nationwide study to evaluate repurposed medications in the search for effective, safe treatments for mild-to-moderate COVID-19. Repurposed medications are those already approved by the U.S. Food and Drug Administration for other indications.

16 Feb 2022

New drug effective in patients with muscle-invasive bladder cancer ineligible for cisplatin chemotherapy

Findings from a new study led by Yale Cancer Center researchers show enfortumab vedotin is effective in patients with muscle-invasive bladder cancer (MIBC) not eligible for cisplatin chemotherapy.

15 Feb 2022

Antiviral potential of N-acylethanolamine acid amide hydrolase against SARS-CoV-2 and Zika virus

A recent study posted to the bioRxiv* pre-print server investigated the antiviral potential of N-acylethanolamine acid amidase (NAAA) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the Zika virus (ZIKV).

14 Feb 2022

Phase one study of oral SARS-CoV-2 antiviral agent nirmatrelvir

A recent study posted to the medRxiv* preprint server reported the phase one pharmacokinetic and safety data of nirmatrelvir/ritonavir to facilitate its rapid progression to the last stages of clinical trials in coronavirus disease 2019 (COVID-19) patients with mild to moderate disease.

14 Feb 2022

Molecular treatment works against metastatic cancer that spread to the brain

Mount Sinai researchers conducting clinical trials of a drug targeting a cancer gene found that it increased metastatic cancer patients' survival and was able to work within the brain, according to a study published in Clinical Cancer Research in February.

10 Feb 2022

Study paves the way for efficient one-dose strategy to reduce scabies prevalence

One dose of an anti-parasite drug was just as effective as two at significantly reducing the spread of scabies, the contagious, intensely itchy skin condition, according to a new study.

10 Feb 2022

New analysis highlights growing trends in combination cancer therapy clinical trials

The Cancer Research Institute, a nonprofit organization dedicated to the discovery and development of powerful immunotherapies for all types of cancer, announced today the publication of its newest analysis of the global landscape of clinical development of drugs that target the PD1/PDL1 immune checkpoint pathway.

10 Feb 2022

Study examines whether viagra-like drug may be effective in treating vascular dementia

A new study, published today in Alzheimer's & Dementia, tested whether tadalafil, a drug closely related to Viagra, may be effective in treating people with vascular dementia.

9 Feb 2022

Two peanut allergy treatments for children found to be highly effective at inducing remission

Researchers have discovered two peanut allergy treatments for children that are both highly effective at inducing remission.

7 Feb 2022

Drug used to treat skin and lung cancers slows the progression of ovarian cancer sub-type

A drug currently used to treat skin and lung cancers has been found to slow the progression of a form of ovarian cancer and increase the number of patients who respond to treatment, a clinical trial has found.

4 Feb 2022

Ketamine is rapid, safe, and effective in treating hospitalized suicidal patients

Ketamine is a fast acting, efficient treatment for patients hospitalized for severe suicidal thoughts (ideation), finds a clinical trial published by The BMJ today.

3 Feb 2022

Nanoparticle vaccine effective against eight SARS-CoV-2 variants in non-human primates

Researchers demonstrate that SARS-CoV-2 RBD-based nanoparticle vaccine induces neutralizing antibodies against SARS-CoV-2 variants.

2 Feb 2022

Experimental immunotherapy could help treat some people with metastatic breast cancer

An experimental form of immunotherapy that uses an individual's own tumor-fighting immune cells could potentially be used to treat people with metastatic breast cancer, according to results from an ongoing clinical trial led by researchers at the National Cancer Institute's Center for Cancer Research, part of the National Institutes of Health.

1 Feb 2022

Individual dosing of preparatory drug makes stem cell transplants safer for children

Individual dosing of a drug used to prepare children for stem cell transplantation makes this treatment safer. That's according to new research by scientists from the Princess Máxima Center and the Wilhelmina Children's Hospital.

1 Feb 2022

Open-label placebo shows promise as therapy for disorders of gut-brain interaction in children

Pain-predominant disorders of gut-brain interaction (DGBIs) in children -; such as functional abdominal pain (FAP) and irritable bowel syndrome (IBS)-; can lead to disabling symptoms, poor quality of life and high use of health care resources.

31 Jan 2022

New trial tests the effectiveness of hyperimmune immunoglobulin for hospitalized COVID-19 patients

This scanning electron microscope image shows SARS-CoV-2 (round gold particles) emerging from the surface of a cell cultured in the lab. SARS-CoV-2, also known as 2019-nCoV, is the virus that causes COVID-19.NIAID

28 Jan 2022

Study provides a new treatment option for patients with relapsed B-cell lymphoma

A new therapy showed improvement over the standard treatment for relapsed B-cell lymphoma, according to a study published in the New England Journal of Medicine.

26 Jan 2022

Homologous and heterologous COVID-19 booster vaccines found to be safe and immunogenic

In adults who had previously received a full regimen of any of three COVID-19 vaccines granted Emergency Use Authorization (EUA) or approved by the U.S. Food and Drug Administration, an additional booster dose of any of these vaccines was safe and prompted an immune response, according to preliminary clinical trial results reported in The New England Journal of Medicine.

26 Jan 2022

More than 5,000 people enrolled in PANORAMIC study for COVID-19 antivirals

Over 5,000 vulnerable people have now enrolled into a world-class study for the chance to receive life-saving antivirals, the government has announced today (Wednesday 26 January 2022).

26 Jan 2022

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Drug Trial News

Treatment found to be safe, efficacious in improving insomnia and night sweats among midlife women

UC joins nationwide trial to evaluate efficacy of repurposed drugs for mild-to-moderate COVID-19

New drug effective in patients with muscle-invasive bladder cancer ineligible for cisplatin chemotherapy

Antiviral potential of N-acylethanolamine acid amide hydrolase against SARS-CoV-2 and Zika virus

Phase one study of oral SARS-CoV-2 antiviral agent nirmatrelvir

Molecular treatment works against metastatic cancer that spread to the brain

Study paves the way for efficient one-dose strategy to reduce scabies prevalence

New analysis highlights growing trends in combination cancer therapy clinical trials

Study examines whether viagra-like drug may be effective in treating vascular dementia

Two peanut allergy treatments for children found to be highly effective at inducing remission

Drug used to treat skin and lung cancers slows the progression of ovarian cancer sub-type

Ketamine is rapid, safe, and effective in treating hospitalized suicidal patients

Nanoparticle vaccine effective against eight SARS-CoV-2 variants in non-human primates

Experimental immunotherapy could help treat some people with metastatic breast cancer

Individual dosing of preparatory drug makes stem cell transplants safer for children

Open-label placebo shows promise as therapy for disorders of gut-brain interaction in children

New trial tests the effectiveness of hyperimmune immunoglobulin for hospitalized COVID-19 patients

Study provides a new treatment option for patients with relapsed B-cell lymphoma

Homologous and heterologous COVID-19 booster vaccines found to be safe and immunogenic

More than 5,000 people enrolled in PANORAMIC study for COVID-19 antivirals

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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