Genomics

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Study identifies how environmental information is transmitted by non-DNA molecules in the sperm

It has long been understood that a parent's DNA is the principal determinant of health and disease in offspring.

16 Mar 2021

Researchers identify a genetic defect that increases the risk of debilitating eye disease

A genetic defect could hold the key to preventing or delaying the onset of a debilitating eye disease that can lead to vision loss and blindness.

16 Mar 2021

Researchers identify epigenetic mechanism responsible for lifelong stress susceptibility

An epigenetic modification that occurs in a major cell type in the brain's reward circuitry controls how stress early in life increases susceptibility to additional stress in adulthood, researchers at the Icahn School of Medicine at Mount Sinai have learned.

15 Mar 2021

Empiric Logic collaborates with UCD to develop novel genomics data protection methodology

Empiric Logic, an Irish bioinformatics SaaS (software-as-a-service) start-up, today announced that is has secured €85,000 in grant funding, under Enterprise Ireland's Innovation Partnership Programme, to develop a novel genomics data protection methodology in collaboration with University College Dublin.

15 Mar 2021

Le Bonheur and UTHSC sign agreement to obtain genetic information from 25,000 DNA samples

As research into genetic causes of disease began to grow, Le Bonheur Pediatrician-in- Chief Jon McCullers, MD, knew it was time to start building a pediatric DNA biorepository.

13 Mar 2021

Novel tool can add or remove sugar from proteins

Sugar has been called "evil," "toxic," and "poison." But the body needs sugars, too. Sugar molecules help cells recognize and fight viruses and bacteria, shuttle proteins from cell to cell, and make sure those proteins function.

12 Mar 2021

Optimized nano-micelles can induce efficient genome editing in the mouse brain

The research group of Deputy Principal Research Scientist Dr. Satoshi Uchida (Associate Professor, Kyoto Prefectural University of Medicine) at the Innovation Center of NanoMedicine (Director General: Prof. Kazunori Kataoka, Location: Kawasaki-Japan, Abbreviation: iCONM) reported that optimized nano-micelles can induce efficient genome editing in the mouse brain.

12 Mar 2021

Deforestation in the Amazon increases diversity of antibiotic-resistant bacteria

In Brazil, a study conducted by researchers affiliated with the University of São Paulo (USP) and collaborators showed that deforestation in the Amazon causes an increase in the diversity of antibiotic-resistant bacteria.

12 Mar 2021

Living in neighborhoods with high rates of violence and poverty alters gene activity

The chronic stress of living in neighborhoods with high rates of violence and poverty alters gene activity in immune cells, according to a new study of low-income single Black mothers on the South Side of Chicago.

12 Mar 2021

Optimized nano-micelles can induce efficient genome editing in the mouse brain

12 Mar 2021

Genetics can partly explain aggressive behavior in children with ADHD with DBDs

An international collaboration headed by researchers from iPSYCH has found genetic variants that increase the risk of aggression in children with ADHD.

11 Mar 2021

Study uncovers 50 new genes for eye color

The genetics of human eye color is much more complex than previously thought, according to a new study published today.

11 Mar 2021

Novel CRISPR-based gene editor developed to correct mutations that cause genetic disorders

A team of researchers from the Agency for Science, Technology and Research's (A*STAR) Genome Institute of Singapore have developed a CRISPR-based gene editor, C-to-G Base Editor (CGBE), to correct mutations that cause genetic disorders.

11 Mar 2021

Study opens the door to new possibilities targeting telomeres to help treat cancer

The Telomeres and Telomerase Group led by Maria A. Blasco at the Spanish National Cancer Research Centre continues to make progress in unraveling the role that telomeres -the ends of chromosomes that are responsible for cellular aging as they shorten- play in cancer.

10 Mar 2021

RNA editing events influence gene expression and phenotypic manifestation

Combining computational mining of big data with experimental testing in the lab, researchers at Children's Hospital of Philadelphia (CHOP) have identified RNA editing events that influence gene expression and, in turn, the phenotypic manifestation of that expression.

10 Mar 2021

First complete atlas of how mutations affect the formation of amyloid plaques in Alzheimer’s disease

A study published in the journal eLife made all the possible mutations in the amyloid beta peptide and tested how they influence its aggregation into plaques, a pathological hallmark of Alzheimer's disease.

9 Mar 2021

Project Helios launched to unlock new approaches in small molecule drug discovery

The University of Texas MD Anderson Cancer Center's Therapeutics Discovery division and Orionis Biosciences today announced the launch of Project Helios, a research collaboration designed to unlock new drug development opportunities through genome-scale mapping of drug-target interactions.

9 Mar 2021

Cooperation between two key genes drives breast cancer growth

Cooperation is generally a good thing -- working together to reach a goal. But in the case of cancer, it can be detrimental. University of Cincinnati researchers have discovered that cooperation between two key genes drives cancer growth, spread and treatment resistance in one particularly aggressive type of breast cancer.

9 Mar 2021

Critical mechanism allows deadly bacteria to gain resistance to antibiotics

Researchers have identified a critical mechanism that allows deadly bacteria to gain resistance to antibiotics.

9 Mar 2021

Diphtheria is evolving to become antibiotic-resistant and could lead to vaccine escape

Diphtheria - a relatively easily-preventable infection - is evolving to become resistant to a number of classes of antibiotics and in future could lead to vaccine escape, warn an international team of researchers from the UK and India.

8 Mar 2021

Genomics

Study identifies how environmental information is transmitted by non-DNA molecules in the sperm

Researchers identify a genetic defect that increases the risk of debilitating eye disease

Researchers identify epigenetic mechanism responsible for lifelong stress susceptibility

Empiric Logic collaborates with UCD to develop novel genomics data protection methodology

Le Bonheur and UTHSC sign agreement to obtain genetic information from 25,000 DNA samples

Novel tool can add or remove sugar from proteins

Optimized nano-micelles can induce efficient genome editing in the mouse brain

Deforestation in the Amazon increases diversity of antibiotic-resistant bacteria

Living in neighborhoods with high rates of violence and poverty alters gene activity

Optimized nano-micelles can induce efficient genome editing in the mouse brain

Genetics can partly explain aggressive behavior in children with ADHD with DBDs

Study uncovers 50 new genes for eye color

Novel CRISPR-based gene editor developed to correct mutations that cause genetic disorders

Study opens the door to new possibilities targeting telomeres to help treat cancer

RNA editing events influence gene expression and phenotypic manifestation

First complete atlas of how mutations affect the formation of amyloid plaques in Alzheimer’s disease

Project Helios launched to unlock new approaches in small molecule drug discovery

Cooperation between two key genes drives breast cancer growth

Critical mechanism allows deadly bacteria to gain resistance to antibiotics

Diphtheria is evolving to become antibiotic-resistant and could lead to vaccine escape

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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