Genomics

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CRISPR gene editing shows promise for treating individuals with a form of inherited blindness

Results from a groundbreaking clinical trial of CRISPR gene editing in 14 individuals with a form of inherited blindness show that the treatment is safe and led to measurable improvements in 11 of the participants treated.

6 May 2024

Genomics plc and GSK collaborate to harness polygenic risk scores in clinical trials

Genomics plc and GSK announced a new collaboration to explore the potential for using polygenic risk scores (PRS) in clinical trials, to improve understanding of disease risk and patient selection, which could support optimization of trial design.

6 May 2024

GenE-HumDi's strategy for involving young scientists in cutting-edge research

COST Actions are meant to be inclusive which means ensuring a geographic spread of participants, encouraging gender balance, and involving young researchers.

3 May 2024

Researchers map early genetic development of the brain

In an article published in Nature, researchers from Karolinska Institutet present an atlas of the early development of the brain.

3 May 2024

Study uncovers causal genetic variant strongly associated with childhood obesity

Researchers from Children's Hospital of Philadelphia (CHOP) have identified a causal genetic variant strongly associated with childhood obesity.

2 May 2024

Healthy lifestyle may offset genetic risks for early death, study finds

Study found that both lifestyle and genetic factors independently influence lifespan, but a healthy lifestyle can reduce the impact of genetic predispositions toward a shorter life.

1 May 2024

Garvan Institute and Illumina collaborate to transform the treatment of complex diseases

Illumina, a global genomics and human health company, has partnered with the Garvan Institute of Medical Research's TenK10K project to help transform the treatment of complex diseases, starting with autoimmune diseases, with a joint investment of $27 million AUD.

30 Apr 2024

Groundbreaking study reveals over 100 new genomic regions linked to blood pressure

National Institutes of Health researchers and collaborators have discovered over 100 new regions of the human genome, also known as genomic loci, that appear to influence a person's blood pressure.

30 Apr 2024

AI-MARRVEL: A leap forward in diagnosing genetic diseases with over 98% precision

The knowledge-driven MARRVEL AI-based model (AIM) to identify Mendelian illnesses.

30 Apr 2024

RNA editing using CRISPRs shows promise for genetic disease treatment

A team at Montana State University published research this week that shows how RNA, the close chemical cousin to DNA, can be edited using CRISPRs.

29 Apr 2024

Study reveals genetic divergence and drug resistance mechanisms in two critical superbugs

Infectious diseases caused by pathogenic strains of bacteria are a global cause of morbidity and mortality. Hospital-acquired infections caused by Klebsiella pneumonia and Pseudomonas aeruginosa were found vulnerable during the COVID-19 pandemic.

29 Apr 2024

Genetic associations of key genes in breast cancer pathogenesis

Breast cancer remains a significant global health concern, warranting further exploration into its genetic basis and potential therapeutic targets.

29 Apr 2024

Unlocking the mechanisms of pluripotent cell's fate determination

As embryos, all complex organisms are partially made up of pluripotent stem cells, a term for cells that have the capacity to differentiate into any kind of cell: nerve cells, muscle cells, blood cells, skin cells, and the like.

29 Apr 2024

SCA4 genetic breakthrough: Unveiling the cause of a devastating neurological disease

Some families call it a trial of faith. Others just call it a curse. The progressive neurological disease known as spinocerebellar ataxia 4 (SCA4) is a rare condition, but its effects on patients and their families can be severe.

29 Apr 2024

New study reveals potential cellular mechanism behind cognitive decline in Alzheimer's

Researchers have developed a robust method for identifying rare brain neurons that re-enter the cell cycle, offering insights into their role in cognitive disorders such as Alzheimer's disease.

28 Apr 2024

Leveraging CRISPR/Cas technology to address antimicrobial resistance

In the second new research review on this subject, Assistant Prof. Ibrahim Bitar, Department of Microbiology, Faculty of Medicine and University Hospital in Plzen, Charles University in Prague, Plzen, Czech Republic, will give an overview of the molecular biology of CRISPR technology in explaining how it can used to tackle antimicrobial resistance.

26 Apr 2024

Largest study of BRCA1 and BRCA2 carriers refines cancer risk estimates in Asian population

A team of clinician-scientists and scientists from the University of Nottingham (Malaysia campus), National Cancer Centre Singapore (NCCS), Cancer Research Malaysia, Nanyang Technological University, Singapore (NTU Singapore), University of Malaya, University of Cambridge, A*STAR's Genome Institute of Singapore (GIS) and other institutions, have conducted the largest study done to date of BRCA1 and BRCA2 (BReast CAncer Gene 1 and 2) carriers in an Asian population and refined breast and ovarian cancer risk estimates for this population.

26 Apr 2024

Genomics

CRISPR gene editing shows promise for treating individuals with a form of inherited blindness

Genomics plc and GSK collaborate to harness polygenic risk scores in clinical trials

GenE-HumDi's strategy for involving young scientists in cutting-edge research

Researchers map early genetic development of the brain

Study uncovers causal genetic variant strongly associated with childhood obesity

Healthy lifestyle may offset genetic risks for early death, study finds

Garvan Institute and Illumina collaborate to transform the treatment of complex diseases

Groundbreaking study reveals over 100 new genomic regions linked to blood pressure

AI-MARRVEL: A leap forward in diagnosing genetic diseases with over 98% precision

RNA editing using CRISPRs shows promise for genetic disease treatment

Study reveals genetic divergence and drug resistance mechanisms in two critical superbugs

Genetic associations of key genes in breast cancer pathogenesis

Unlocking the mechanisms of pluripotent cell's fate determination

SCA4 genetic breakthrough: Unveiling the cause of a devastating neurological disease

New study reveals potential cellular mechanism behind cognitive decline in Alzheimer's

Leveraging CRISPR/Cas technology to address antimicrobial resistance

Largest study of BRCA1 and BRCA2 carriers refines cancer risk estimates in Asian population

Machine learning-powered robot streamlines genetic research process

Yeast study reveals evolutionary history of iron uptake mechanisms

Multi-omics approach powers Karolinska Institutet's Single Cell Atlas

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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