Genomics

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Improving Lab Productivity with Temperature Control

Polyscience CEO Philip Preston discusses the importance of temperature control and how Polyscience solutions can improve lab productivity for researchers.

From PolyScience 1 Mar 2019

Many genes contribute to risk for Tourette's syndrome, genetic study shows

A meta-analysis of multiple studies into the genetic background of Tourette's syndrome (TS) - a neurodevelopmental disorder characterized by chronic involuntary motor and vocal tics - finds that variants in hundreds of genes, working in combination, contribute to the development of the syndrome and suggests that Tourette's is part of a continuous spectrum of tic disorders, ranging from mild, sometimes transient tics to severe cases that can include psychiatric symptoms.

1 Mar 2019

Custom-made proteins could result in antibodies that fight HIV

Researchers have developed a new method for the creation of custom-made proteins that can bypass the protective coating of the HIV virus.

28 Feb 2019

Second-ever case of semi-identical (sesquizygotic) twins

Doctors report on a woman who gave birth to semi-identical twins in 2014. This is the second time this is known to have occurred after the first case in 2007.

28 Feb 2019

Researchers analyze differing antioxidant levels in tomatoes of different colors

Naturally occurring antioxidants have been of great interest in recent years due to their recognizable health benefits. A study out of Universidad Autónoma Metropolitana in Mexico has clarified differing antioxidant levels by focusing on eight tomato genotypes with different-color fruit.

28 Feb 2019

Biologists uncover mechanism that determines faithful inheritance of short chromosomes

A team of biologists has uncovered a mechanism that determines faithful inheritance of short chromosomes during the reproductive process.

27 Feb 2019

Key to treat deadly cancers could lie deep within complex machinery of human cell

Buried deep within the dazzlingly intricate machinery of the human cell could lie a key to treating a range of deadly cancers, according to a team of scientists at Florida State University.

27 Feb 2019

Cancer genes’ mutational status influenced by their evolutionary age, regulatory functions

Researchers have provided new insight on why some genes that formed during the evolution of the earliest animals on earth are particularly impaired (or dysregulated) by specific mechanisms during cancer development.

26 Feb 2019

Novel mechanism behind DNA damage control uncovered

DNA damage is occurring in our cells all the time due to external agents, such as exposure to sun, or internal agents, like reactive oxygen species.

26 Feb 2019

Scientists use CRISPR to reveal the secret life of antimicrobial peptides

When it comes to the immune system, we usually think about lymphocytes like B and T cells or macrophages going on constant seek-and-destroy missions against invading pathogens like bacteria and viruses.

26 Feb 2019

Scientists report new and improved method to detect chemical modifications to DNA

Ludwig Cancer Research scientists report in the current issue of Nature Biotechnology a new and improved method to detect chemical modifications to DNA.

26 Feb 2019

Researchers uncover possibility of acoustic side-channel attack on DNA synthesis process

During the DNA synthesis process in a laboratory, recordings can be made of the subtle, telltale noises made by synthesis machines. And those captured sounds can be used to reverse-engineer valuable, custom-designed genetic materials used in pharmaceuticals, agriculture and other bioengineering fields.

25 Feb 2019

Lack of diversity in cell lines does not allow minorities to reap the benefits of precision medicine

As the biomedical field races to develop therapies based on an individual's genetic makeup, a City of Hope scientist and his colleagues found that some commercial cell lines used for countless laboratory studies have mislabeled ancestry when it comes to minorities.

25 Feb 2019

The gene-edited twins born in China may have altered cognition and memory

A new study has fuelled further concerns over the controversial gene-editing experiment that was performed in China last year.

22 Feb 2019

UVA scientist receives $1 million award to map out submicroscopic world

A scientist at the University of Virginia School of Medicine has received a prestigious three-year, $1 million award from the William M. Keck Foundation to develop a new and better way to map out the submicroscopic world.

22 Feb 2019

Mitochondrial proteotoxicity appears to be epicentre of molecular pathogenesis

Researchers at the University of Helsinki uncovered the mechanisms for a novel cellular stress response arising from the toxicity of newly synthesized proteins.

22 Feb 2019

Researchers discover several genes linked to increased use of alcohol and tobacco

The use of alcohol and tobacco is closely linked to several diseases, and is a contributing factor in many deaths.

21 Feb 2019

Study quantifies hepatic and intestinal mRNA expression of Ugt isoforms in rats

In pharmaceutical companies, rats are used commonly in nonclinical studies to investigate the safety, efficacy, and pharmacokinetic profiles of drug candidates before they are entered into clinical studies. Most compounds administered via the oral route are metabolized in the liver and intestine, so the metabolism is a key determinant of pharmacokinetics.

20 Feb 2019

Researchers unlock the secret behind reproduction of fish called ‘Mary’

A female stickleback fish, nick-named 'Mary', has produced offspring from eggs that appear to have been fertilized while they were still inside her, according to scientists at the University of Nottingham.

20 Feb 2019

Mogrify to accelerate novel IP and cell therapies using $3.7m USD funding

Mogrify today announced a second close on its seed funding, bringing the total raised to $3.7 million USD, and the appointment of Darrin Disley as CEO.

20 Feb 2019

Genomics

Improving Lab Productivity with Temperature Control

Many genes contribute to risk for Tourette's syndrome, genetic study shows

Custom-made proteins could result in antibodies that fight HIV

Second-ever case of semi-identical (sesquizygotic) twins

Researchers analyze differing antioxidant levels in tomatoes of different colors

Biologists uncover mechanism that determines faithful inheritance of short chromosomes

Key to treat deadly cancers could lie deep within complex machinery of human cell

Cancer genes’ mutational status influenced by their evolutionary age, regulatory functions

Novel mechanism behind DNA damage control uncovered

Scientists use CRISPR to reveal the secret life of antimicrobial peptides

Scientists report new and improved method to detect chemical modifications to DNA

Researchers uncover possibility of acoustic side-channel attack on DNA synthesis process

Lack of diversity in cell lines does not allow minorities to reap the benefits of precision medicine

The gene-edited twins born in China may have altered cognition and memory

UVA scientist receives $1 million award to map out submicroscopic world

Mitochondrial proteotoxicity appears to be epicentre of molecular pathogenesis

Researchers discover several genes linked to increased use of alcohol and tobacco

Study quantifies hepatic and intestinal mRNA expression of Ugt isoforms in rats

Researchers unlock the secret behind reproduction of fish called ‘Mary’

Mogrify to accelerate novel IP and cell therapies using $3.7m USD funding

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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