Genomics

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The role of CRISPR-Cas9 in combating mosquito-borne diseases

Announcing a new article publication for Zoonoses journal. As global warming increases, mosquito activity areas are expanding, alongside changes in the natural environment and the misuse of insecticides, thus further increasing mosquito resistance and exposing the world to an elevated risk of mosquito-borne diseases.

23 Sep 2024

Enhanced TnpB protein offers new possibilities for gene editing

CRISPR-Cas is used broadly in research and medicine to edit, insert, delete or regulate genes in organisms. TnpB is an ancestor of this well-known "gene scissor" but is much smaller and thus easier to transport into cells.

23 Sep 2024

Key genetic factors linked to severe cholera symptoms discovered

Experts have used a cutting-edge computational approach to discover the genetic factors that make the bacteria behind cholera so dangerous - which could be key to preventing this deadly disease.

23 Sep 2024

Study uncovers novel genetic variant associated with intellectual disability

Researchers at the Icahn School of Medicine at Mount Sinai have published a pivotal study in Nature Genetics (DOI: 10.1038/s41588-024-01917-1) that sheds light on a novel genetic variant associated with intellectual capacities and educational outcomes.

23 Sep 2024

Genetic factors drive fussy eating from toddlerhood to adolescence

Fussy eating is mainly influenced by genes and is a stable trait lasting from toddlerhood to early adolescence, finds a new study led by researchers from UCL (University College London), King's College London and the University of Leeds.

19 Sep 2024

Chan Zuckerberg initiative joins Scale Bio's ‘100 Million Cell Challenge’ to accelerate single cell genomics research

The '100 Million Cell Challenge' invites proposals for large-scale single cell studies, with CZI funding 50 million cells to accelerate scientific discoveries.

19 Sep 2024

Scientists pinpoint thousands of gene variants linked to breast and ovarian cancer risk

Scientists have pinpointed thousands of genetic changes in a gene that may increase a person's risk of developing breast and ovarian cancer, paving the way for better risk assessment and more personalised care.

18 Sep 2024

Discovery of 5-formylcytosine as an activating epigenetic switch

The team of Professor Christof Niehrs at the Institute of Molecular Biology (IMB) in Mainz, Germany, has discovered that a DNA modification called 5-formylcytosine (5fC) functions as an activating epigenetic switch that kick-starts genes in early embryonic development.

18 Sep 2024

Genome-wide association study identifies genetic risk factors for dementia

In landmark research, scientists at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) have reported the largest-ever genome-wide association study of dementia from all causes, revealing an overlap of genetic risks including neurodegeneration, vascular factors and cerebral small-vessel disease.

18 Sep 2024

Discovery of gene variant could transform treatment for newborn jaundice

One in eight newborn babies has a gene variant that almost completely protects against jaundice. The research, conducted at the University of Gothenburg in Sweden, provides the opportunity to develop a treatment that can prevent severe cases of jaundice.

17 Sep 2024

Unveiling the mechanism behind DNA organization in early embryos

Researchers from the Kind Group have gained new insights into the mechanism behind the spatial organization of DNA within the cells of early embryos.

16 Sep 2024

Soil pH and toxicity influence microbial community composition in new study

Though a founding concept of ecology suggests that the physical environment determines where organisms can survive, modern scientists have suspected there is more to the story of how microbial communities form in the soil.

13 Sep 2024

Study finds brain synchronization between humans and dogs during social interactions

During social interactions, the activity of the brain's neurons becomes synchronized between the individuals involved.

13 Sep 2024

Five key factors identified for predicting immunotherapy response in cancer patients

Immunotherapy has transformed cancer treatment in recent years by enabling the immune system to attack tumor cells.

12 Sep 2024

Four genes found to significantly influence menopause timing and cancer risk

New research has found four genes with some of the largest known effects on the timing of menopause discovered to date, providing new insight into links between menopause timing and cancer risk.

11 Sep 2024

Scripps Research develops breakthrough technique for adding unique amino acids to proteins

It's a dogma taught in every introductory biology class: Proteins are composed of combinations of 20 different amino acids, arranged into diverse sequences like words.

11 Sep 2024

Study on Arabidopsis thaliana plants reveals new insights into epigenetic regulation

One of the most fascinating discoveries in biology is that cells have mechanisms for dynamically regulating genetic expression.

11 Sep 2024

VitelloTag approach offers new solution for gene editing challenges in egg cells

A new approach for delivering miniature research tools into the interior of egg cells and embryos has been developed at the Marine Biological Laboratory (MBL), resolving a major bottleneck to using the gene-editing tool CRISPR-Cas9 in many research organisms.

11 Sep 2024

New molecular map offers insights into human physiology and disease

Scientists at Weill Cornell Medicine in Qatar (WCM-Q) have created an intricate molecular map of the human body and its complex physiological processes based on the analysis of thousands of molecules measured in blood, urine and saliva samples from 391 volunteers.

11 Sep 2024

TAAR1 gene: A new key to mental health

In the complex landscape of mental health research, a new peer-reviewed Viewpoint review sheds light on an underexplored genetic player: the trace amine-associated receptor 1 (TAAR1). Published in Genomic Psychiatry (ISSN: 2997-2388, Genomic Press, New York), this thought-provoking analysis suggests that mutations in the TAAR1 gene may be a crucial piece of the puzzle in understanding and treating neuropsychiatric disorders.

11 Sep 2024