Genomics

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VAI scientists uncover mechanism that annotates genetic information passed from fathers to offspring

Van Andel Institute scientists and collaborators have identified a key part of a mechanism that annotates genetic information before it is passed from fathers to their offspring.

7 Sep 2023

RIT researchers use CRISPR to develop new treatment for degenerative disc disease

Rochester Institute of Technology researchers are improving non-invasive treatment options for degenerative disc disease, an ailment that impacts 3 million adults yearly in the U.S., according to the Mayo Clinic.

6 Sep 2023

Cornell biologists shine light on the possible origin of differences in human social behaviors

Male fruit flies don't usually like each other. Socially, they reject their fellow males and zero in on the females they discern via chemical receptors – or so scientists thought.

5 Sep 2023

NGS-based screening identifies rare and novel thalassemia mutations in Ganzhou, China

Around 5.2% of the global population carries abnormal hemoglobin genes. Each year, 300,000 to 500,000 children are born with severe hemoglobinopathies worldwide, with approximately 80% of these cases occurring in developing countries.

5 Sep 2023

Silencing two genes can make cancer cells receptive to chemotherapy

Scientists from Queen Mary University of London have discovered two new genes that cause head and neck cancer patients to be resistant to chemotherapy, and that silencing either gene can make cancer cells previously unresponsive to chemotherapy subsequently respond to it.

4 Sep 2023

Some communities express mistrust and cynicism in response to conversations about genomics

New research published today in Human Genetics and Genomics Advances reveals the difference between ‘what we say’ and ‘what people hear’ when engaging underrepresented communities around genomics and healthcare.

4 Sep 2023

Innovate UK funding to support the development of powdered gene therapy for bone graft augmentation

TherageniX, a University of Nottingham spin out pioneering a dry powder gene therapy formulation for bone graft augmentation, and its collaborator, the University of Nottingham, have been awarded a £995,000 grant from Innovate UK, the UK’s innovation agency.

4 Sep 2023

Ancient population bottleneck revealed by new genomic study

Between 800,000 and 900,000 years ago, the population of human ancestors crashed, according to a new genomic model by Wangjie Hu and colleagues.

31 Aug 2023

Largest genetic study of epilepsy finds new risk genes

The largest genetic study of its kind, coordinated by the International League Against Epilepsy, including scientists from FutureNeuro at RCSI University of Medicine and Health Sciences, has discovered specific changes in our DNA that increase the risk of developing epilepsy.

31 Aug 2023

The Clinical Importance of Circulating Tumor DNA

Cancer remains a leading killer among medical causes of death worldwide.

31 Aug 2023

Study reveals biological mechanism behind the impact of fathers' early teenage smoking on offspring

A new study suggests boys who smoke in their early teens risk damaging the genes of their future children, increasing their chances of developing asthma, obesity and low lung function.

30 Aug 2023

INTEGRA Biosciences' vacuum aspiration systems help researchers solve the dog epigenome

Researchers in the Cho Lab at Seoul National University’s College of Veterinary Medicine, are using the VACUSAFE safe aspiration system and VACUSIP portable aspiration system from INTEGRA Biosciences to help them culture organoids from cancer-stricken domesticated dogs as part of a comparative medicine research initiative.

From INTEGRA Biosciences 30 Aug 2023

Scale Biosciences Continues Commercial Expansion with Introduction of New and Differentiated Single Cell Methylation and Single Cell RNA Sequencing Solutions

Scale Biosciences, Inc. (ScaleBioTM), an innovator in single cell sequencing leveraging combinatorial indexing technologies, today announced an expansion of their product portfolio to enable a broader range of single cell omics experiments and unlock new translational research applications.

30 Aug 2023

Gene therapy reduces hearing loss associated with Norrie disease in mice

An international team led by researchers at UCL and the NIHR Great Ormond Street Hospital Biomedical Research Centre have developed in mice a gene therapy that significantly reduces the hearing loss associated with Norrie disease.

29 Aug 2023

Dual CRISPR-Cas3 is a promising tool to induce a gigantic genomic deletion and restore dystrophin protein

Researchers evaluated the use of a dual clustered regularly interspaced short palindromic repeats (CRISPR)-Cas3 system.

29 Aug 2023

Ciliopathies: A new understanding of the role of the NSL complex

The non-specific lethal (NSL) complex is a chromatin-associated factor that has been shown to regulate the expression of thousands of genes in both fruit flies and mammals.

25 Aug 2023

Kennesaw State professor receives NIH grant to study epigenetic inheritance in nematodes

Kennesaw State University biology professor Brandon Carpenter was inspired to pursue a career in science because of an undergraduate research experience. With a recent grant from the National Institutes of Health (NIH), he'll provide a similar experience to his students.

25 Aug 2023

Genomics

VAI scientists uncover mechanism that annotates genetic information passed from fathers to offspring

RIT researchers use CRISPR to develop new treatment for degenerative disc disease

Cornell biologists shine light on the possible origin of differences in human social behaviors

NGS-based screening identifies rare and novel thalassemia mutations in Ganzhou, China

Silencing two genes can make cancer cells receptive to chemotherapy

Some communities express mistrust and cynicism in response to conversations about genomics

Innovate UK funding to support the development of powdered gene therapy for bone graft augmentation

Ancient population bottleneck revealed by new genomic study

Largest genetic study of epilepsy finds new risk genes

The Clinical Importance of Circulating Tumor DNA

Study reveals biological mechanism behind the impact of fathers' early teenage smoking on offspring

INTEGRA Biosciences' vacuum aspiration systems help researchers solve the dog epigenome

Scale Biosciences Continues Commercial Expansion with Introduction of New and Differentiated Single Cell Methylation and Single Cell RNA Sequencing Solutions

Gene therapy reduces hearing loss associated with Norrie disease in mice

Dual CRISPR-Cas3 is a promising tool to induce a gigantic genomic deletion and restore dystrophin protein

Ciliopathies: A new understanding of the role of the NSL complex

Kennesaw State professor receives NIH grant to study epigenetic inheritance in nematodes

Two small molecule inhibitors can help improve precision, efficiency of CRISPR-Cas9 gene editing

Midnolin protein plays key role in breaking down short-lived nuclear proteins

Genetics and environment influence immune responses to SARS-CoV-2

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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