Genomics

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Chickpea's secret history: How trade routes and migrations shaped the legume's genetic heritage

With its nutty flavor and dense nutrient profile, the humble chickpea has captivated palates and nourished civilizations for millennia.

23 Jun 2023

Cell and gene therapy CDMO Andelyn Biosciences celebrates over 20 years of leadership and innovation with opening of new 180,000 square foot manufacturing headquarters

Andelyn Biosciences, a pioneer in the development and manufacturing of cell and gene therapies, today formally inaugurates its new manufacturing headquarters, the Andelyn Corporate Center (ACC), located in the Innovation District in Columbus, Ohio.

From Andelyn Biosciences 23 Jun 2023

New embryonic cell type that self-destructs to protect the developing fetus discovered

Scientists studying gene activity data of the early human embryo have discovered an overlooked type of cell which self-destructs within days of forming, as part of a quality control process to protect the developing fetus.

20 Jun 2023

Scientists develop new technique to peer into the genome's spatial architecture

People who owned black-and-white television sets until the 1980s didn't know what they were missing until they got a color TV.

19 Jun 2023

Genetic mechanisms that underlie healthy high-elevation pregnancies may have deep evolutionary roots

Pregnancy at high elevations often is associated with low birth weights and other complications. These challenges occur in a wide range of mammals, from deer mice to human beings.

16 Jun 2023

MGI Partners with Xpress Genomics to Advance Deep Single-cell RNA-Sequencing Technologies

MGI, a company committed to building core tools and technology to lead life science, announced the signing of a licensing agreement with Xpress Genomics, a leading Stockholm-based company specializing in automated and scalable RNA-sequencing strategies.

From MGI 16 Jun 2023

Penn research bolsters scientific understanding behind why some people are more prone to allergies

New research is bolstering scientific understanding behind why some people are more prone to allergies than others.

15 Jun 2023

Innovative method to map specific DNA markings could be used for early cancer detection

Researchers from the Perelman School of Medicine at the University of Pennsylvania have invented a new way to map specific DNA markings called 5-methylcytosine (5mC) which regulate gene expression and have key roles in health and disease.

15 Jun 2023

COVID-19 susceptibility mechanism discovered using a newly created tool

Researchers have discovered a mechanism for COVID-19 susceptibility using a newly created tool. The tool, GASPACHO, captures dynamic changes in gene expression along the innate immune response, allowing researchers to identify genes and molecular pathways associated with disease risk that have previously been too complex to detect or interpret.

15 Jun 2023

New findings expand the genotypic spectrum of NPRL3-associated focal epilepsy

Science China Life Sciences magazine recently reported on the research results of Tang Beisha's team from Xiangya Hospital of Central South University, Liu Jing Yu's team from the Institute of Neurology of the Chinese Academy of Sciences, and Zhang Luoying's team from Huazhong University of Science and Technology, including Du Shiyue, Zeng Sheng, and Song Li. Epilepsy has a complex etiology with 80% owing a genetic basis.

15 Jun 2023

Mapping the evolutionary timeline and population distribution of E. coli’s protective outer capsule

In a new study, published today (15 June) in Nature Communications, a multi-centre team led by the Wellcome Sanger Institute, the University of Oslo, Imperial College London and UCL, has mapped for the first time the evolutionary timeline and population distribution of Escherichia coli’s protective outer capsule, which is responsible for the bacterium’s virulence.

15 Jun 2023

CrossDome tool helps predict the potential risks of T-cell immunotherapy

Researchers at the University of Houston are working to make T-cell immunotherapy safer, developing a tool called CrossDome, which uses a combination of genetic and biochemical information to predict if T-cell immunotherapies might mistakenly attack healthy cells.

14 Jun 2023

Scientists show how pregnancy induces progressive changes in the maternal immune system

We have a good understanding of how a woman's external features can change during pregnancy, but scientists know surprisingly little about what biological changes occur internally.

13 Jun 2023

Heat-damaged DNA in food may contribute to genetic risks

Researchers have newly discovered a surprising and potentially significant reason why eating foods frequently cooked at high temperatures, such as red meat and deep-fried fare, elevates cancer risk. The alleged culprit: DNA within the food that's been damaged by the cooking process.

13 Jun 2023

New process for creating a “meta-cell overcomes the challenges of studying single-cell secrets

University of California, Irvine neuroscientists probing the gene changes behind Alzheimer's disease have developed a process of making a "meta-cell" that overcomes the challenges of studying a single cell.

13 Jun 2023

Study shows link between death perception and reduced aging in flies

Researchers led by Christi Gendron at the University of Michigan, US, have found the link between death perception and reduced aging in flies.

13 Jun 2023

DYRK1A gene may dictate susceptibility to multiple highly pathogenic coronaviruses

Entry of the SARS-CoV-2 virus into human tissues depends on the activity of a host gene that regulates production of a key viral receptor, according to a study publishing June 13th in the open access journal PLOS Biology by Madison Strine and Craig Wilen of Yale University, US, and colleagues.

13 Jun 2023

Tracing the ancestry of hybrids using a new method

If you've ever kept a garden, you're probably familiar with hybrids, from disease-resistant tomatoes to Stargazer lilies.

13 Jun 2023

ACMG publishes updated recommendations for CFTR carrier screening

The American College of Medical Genetics and Genomics (ACMG) has released updated recommendations for CFTR carrier screening –Updated recommendations for CFTR carrier screening: A position statement of the American College of Medical Genetics and Genomics.

13 Jun 2023

"Homing gene drive system" could help suppress agricultural pests

Researchers have developed a "homing gene drive system" based on CRISPR/Cas9 that could be used to suppress populations of Drosophila suzukii vinegar flies – so-called "spotted-wing Drosophila" that devastate soft-skinned fruit in North America, Europe and parts of South America – according to new research from North Carolina State University.

12 Jun 2023

Genomics

Chickpea's secret history: How trade routes and migrations shaped the legume's genetic heritage

Cell and gene therapy CDMO Andelyn Biosciences celebrates over 20 years of leadership and innovation with opening of new 180,000 square foot manufacturing headquarters

New embryonic cell type that self-destructs to protect the developing fetus discovered

Scientists develop new technique to peer into the genome's spatial architecture

Genetic mechanisms that underlie healthy high-elevation pregnancies may have deep evolutionary roots

MGI Partners with Xpress Genomics to Advance Deep Single-cell RNA-Sequencing Technologies

Penn research bolsters scientific understanding behind why some people are more prone to allergies

Innovative method to map specific DNA markings could be used for early cancer detection

COVID-19 susceptibility mechanism discovered using a newly created tool

New findings expand the genotypic spectrum of NPRL3-associated focal epilepsy

Mapping the evolutionary timeline and population distribution of E. coli’s protective outer capsule

CrossDome tool helps predict the potential risks of T-cell immunotherapy

Scientists show how pregnancy induces progressive changes in the maternal immune system

Heat-damaged DNA in food may contribute to genetic risks

New process for creating a “meta-cell overcomes the challenges of studying single-cell secrets

Study shows link between death perception and reduced aging in flies

DYRK1A gene may dictate susceptibility to multiple highly pathogenic coronaviruses

Tracing the ancestry of hybrids using a new method

ACMG publishes updated recommendations for CFTR carrier screening

"Homing gene drive system" could help suppress agricultural pests

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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