Histology & Microscopy

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Malaria crystal structure offers clues for more effective medications

Prof. Leslie Leiserowitz first became intrigued by malaria when he was a young boy in South Africa. His father, who scouted the continent in search of wood for the family business, brought back not only tales of elephants and gorillas but also skin rashes and ringing in his ears, side effects of the quinine he took to prevent malaria.

19 Nov 2024

TB pathogen's surprising growth mechanism challenges bacterial biology

The rod-shaped tuberculosis (TB) bacterium, which the World Health Organization has once again ranked as the top infectious disease killer globally, is the first single-celled organism ever observed to maintain a consistent growth rate throughout its life cycle.

15 Nov 2024

DEEPscope breaks barriers in deep-tissue brain imaging

Researchers at Cornell have unveiled an advanced imaging technology capable of unprecedented deep and wide-field visualization of brain activity at single-cell resolution.

6 Nov 2024

Mapping tumor microenvironments: Uncovering spatial subclones for improved cancer treatment

Researchers investigate the spatial organization of cancer cells and the tumor microenvironment.

31 Oct 2024

Deep learning techniques transform protein structure prediction

In the rapidly advancing field of computational biology, a newly peer-reviewed review explores the transformative role of deep learning techniques in revolutionizing protein structure prediction.

30 Oct 2024

New imaging technique revolutionizes microplastics detection in biological samples

Microplastics, pervasive in both terrestrial and aquatic environments, have been found in diverse organisms, from fish and plants to humans.

28 Oct 2024

Novel findings on GRB2 and SOS1 could pave the way for cancer treatments

Researchers from Tokyo Metropolitan University have uncovered new insights into how the proteins GRB2 and SOS1 in cells pass signals from membrane receptors to nuclei.

26 Oct 2024

High-throughput imaging platform reveals impact of mutations on protein location

The team developed a high-throughput imaging platform to assess the influence of nearly 3,500 mutations on protein location. They found that roughly one in six disease-causing mutations led to proteins ending up in the wrong location in the cell.

26 Oct 2024

Researchers decode MRSA biofilm structure to combat antibiotic resistance

Imagine falling seriously ill with an infection. Normally, we visit the doctor, are prescribed antibiotics, and after 7-10 days, we're back on our feet.

24 Oct 2024

New insights into how gene transcription influences genome motion

A team of scientists has discovered surprising connections among gene activity, genome packing, and genome-wide motions, revealing aspects of the genome's organization that directly affect gene regulation and expression.

22 Oct 2024

Discovery of new bacterial toxins opens path to novel infection treatments

Researchers have discovered a new group of bacterial toxins that can kill harmful bacteria and fungi, opening the door to potential new treatments for infections.

22 Oct 2024

Breakthrough in understanding microtubule formation in cells

Inside every cell, a network of tiny filaments, called the microtubule cytoskeleton, helps maintain the cell's shape, allows it to divide, and transports vital materials from one part of the cell to another.

15 Oct 2024

Comprehensive review finds AI's influence on hospital efficiency lacks clarity

The use of artificial intelligence (AI) in hospitals and patient care is steadily increasing. Especially in specialist areas with a high proportion of imaging, such as radiology, AI has long been part of everyday clinical practice.

12 Oct 2024

Innovative tissue expansion technique transforms conventional microscopy capabilities

A classical way to image nanoscale structures in cells is with high-powered, expensive super-resolution microscopes. As an alternative, MIT researchers have developed a way to expand tissue before imaging it -; a technique that allows them to achieve nanoscale resolution with a conventional light microscope.

12 Oct 2024

Understanding proteasome function in Trichomonas vaginalis for drug development

Researchers from IOCB Prague are furthering the understanding of how medicines work and what it takes to develop their most effective variants.

8 Oct 2024

New UCL hub to advance cancer detection with imaging tech

UCL will lead a £17 million surgical imaging hub to improve cancer detection and take part in a £12 million collaboration to help solve age and disability-related mobility issues, in a major funding award from the UKRI Engineering and Physical Sciences Research Council (EPSRC).

8 Oct 2024