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Machine learning helps predict stroke risk after CF-LVAD implantation

Some patients with advanced heart failure can benefit from the support of a continuous-flow left ventricular assist device (CF-LVAD) to sustain heart function. However, despite improvements managing complications associated with the use of CF-LVADs, stroke continues to be a major adverse event after the implantation of the device.

12 Nov 2024

Georgia Tech researchers create lab-grown models of human immune systems

To better understand why some cancer patients struggle to fight off infections, Georgia Tech researchers have created tiny lab-grown models of human immune systems.

12 Nov 2024

MUSC team develops digital toolkit to screen for intimate partner violence and PTSD in opioid use disorder

The opioid crisis has left an estimated 2.5 million people 18 and older in the U.S. with opioid use disorder, or OUD. Despite increased attention to the heavy toll taken by OUD, key risk factors such as intimate partner violence (IPV) and post-traumatic stress disorder (PTSD) are often overlooked. Both increase the risk of OUD and complicate recovery efforts.

12 Nov 2024

Early genomic profiling improves cancer treatment outcomes

New real-world data from Providence, Illumina, and Microsoft Research reveals that Comprehensive Genomic Profiling (CGP), when done early in a cancer patient's diagnosis, leads to better personalized treatment and patient outcomes.

12 Nov 2024

Updated recommendations stress importance of CPR for drowning victims

Updated guidance reaffirms the recommendation for cardiopulmonary resuscitation (CPR) and highlights the importance of compressions with rescue breaths as a first step in responding to cardiac arrest following drowning, according to a new, focused update to Special Circumstances Guidelines from the American Heart Association and the American Academy of Pediatrics.

12 Nov 2024

New treatment combination improves outcomes for small cell bladder and prostate cancer patients

A research team led by UCLA Health Jonsson Comprehensive Cancer Center investigators has shown that that combining pembrolizumab, an immunotherapy drug, with standard chemotherapy can improve treatment outcomes for patients with small cell bladder cancer and small cell/neuroendocrine prostate cancer.

12 Nov 2024

Vitamin D supplementation may decrease blood pressure in obese older adults

Vitamin D supplements may lower blood pressure in older people with obesity and taking more than the Institutes of Medicine's (IOM) recommended daily dose does not provide additional health benefits, according to new research published in the Journal of the Endocrine Society.

12 Nov 2024

New blood test detects early lung damage in cancer patients on targeted therapy

New study introduces a simple blood test to detect early lung damage in cancer patients receiving novel therapy with antibody-drug conjugates (ADCs), which can sometimes cause serious, even fatal, lung disease (ILD).

12 Nov 2024

Metabolic enzymes take on unexpected roles in cell division and DNA repair

Researchers at the Centre for Genomic Regulation (CRG) reveal that metabolic enzymes known for their roles in energy production and nucleotide synthesis are taking on unexpected "second jobs" within the nucleus, orchestrating critical functions like cell division and DNA repair.

12 Nov 2024

New study highlights the importance of BMI in disease pathogenesis

New study from deCODE genetics/Amgen highlights the importance of BMI in pathogenesis of disease, suggesting that reducing BMI alone could lower the risk of several diseases.

12 Nov 2024

Digital health technologies play a transformative role in diabetes management and prevention

Scientists at Pennington Biomedical Research Center, along with a colleague from Peking University People's Hospital in China, have been leading a special collection and published an editorial in Frontiers in Endocrinology, emphasizing the transformative role digital health technologies play in diabetes management and prevention.

12 Nov 2024

Imbalances in NET homeostasis linked to portal vein thrombosis in CHB-related decompensated cirrhosis

Portal vein thrombosis (PVT) is a challenging complication in liver cirrhosis, with no currently available sensitive diagnostic markers.

12 Nov 2024

TYK2 inhibition may offer new strategy to reduce tau toxicity in Alzheimer's

Researchers at Baylor College of Medicine, the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital and collaborating institutions discovered that the enzyme TYK2 transforms the normal protein tau into one that accumulates in the brain and contributes to the development of Alzheimer's disease in animal models.

12 Nov 2024