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Transcranial magnetic stimulation can be a cost-effective treatment option for depression

A major new study has found that transcranial magnetic stimulation (TMS), which applies magnetic energy to the brain, can be a cost-effective treatment option for the NHS in treating moderate and severe forms of depression that have not responded to other treatments.

27 Jan 2026

Silencing a specific brain circuit can prevent and reverse chronic pain

A neural circuit hidden in an understudied region of the brain plays a critical role in turning temporary pain into pain that can last months or years, according to new University of Colorado Boulder research.

27 Jan 2026

Study isolates mania-specific genetic architecture in bipolar disorder

Researchers at King's College London and the University of Florence have, for the first time, identified the specific genetic blueprint of mania, the defining feature of bipolar disorder.

27 Jan 2026

Sleeping without pillows may help reduce nighttime eye pressure in glaucoma

Sleeping without pillows may help lower high internal eye pressure, build-up of which causes optic nerve damage and glaucoma-the leading cause of irreversible blindness worldwide–in people with the condition, suggests preliminary research, published online in the British Journal of Ophthalmology.

27 Jan 2026

Clinical trial aims to improve survival for patients with recurrent head and neck cancer

A newly approved National Cancer Institute-funded clinical trial aims to improve survival for head and neck cancer patients whose disease returns after radiation therapy – a setback that affects up to 40% of patients and is often associated with poor outcomes.

27 Jan 2026

First topical CRISPR gene therapy corrects disease-causing mutations in human skin

Gene-editing tools like CRISPR have unlocked new treatments for previously uncurable diseases. Now, researchers at the University of British Columbia are extending those possibilities to the skin for the first time.

27 Jan 2026

Antibody-producing plasma cells shape effectiveness of PD-1 immunotherapy

Scientists at the Icahn School of Medicine at Mount Sinai have identified an important immune response that helps explain why some cancer patients benefit from immunotherapy while others do not.

27 Jan 2026

Overactive protein cleanup disrupts nuclear pores in neurodegenerative disease

When it comes to neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and certain forms of dementia, researchers have known that protein quality control and damage to the nuclear pore are key players.

27 Jan 2026

Immune system dysfunction may fuel progressive heart failure after heart attacks

When the heart's muscle is weakened or injured due to a heart attack, it can make it hard for the heart to pump enough blood to meet the body's needs.

27 Jan 2026

MRI measures of glymphatic activity may improve noninvasive intracranial hypertension diagnosis

A new study led by investigators from Mass General Brigham shows that a brain waste- "clean-up" system is influenced by intracranial pressure.

27 Jan 2026

Study reveals heart, brain, neuroimmune connections driving damage after heart attacks

Arteries become clogged. Blood flow is restricted and oxygen is cut off. The result is a heart attack, the world's leading cause of death.

27 Jan 2026

Insilico Medicine and Qilu Pharmaceutical partner to develop AI-designed cardiometabolic drugs

Insilico Medicine, a clinical-stage biotechnology company powered by generative AI, and Qilu Pharmaceutical Group, a major comprehensive modern pharmaceutical enterprise in China, as well as its subsidiary Shanghai Qilu Pharmaceutical Research Center, today announced a strategic partnership on innovative drug development, leveraging Insilico's proprietary Pharma.AI platform to jointly develop small molecule inhibitors, focusing on specific targets for cardiometabolic disease management.

27 Jan 2026

Gut problems may shape Parkinson’s disease progression through the gut-brain axis

This narrative review examines how gastrointestinal dysfunction, gut dysbiosis, and altered gut-brain axis signaling are closely associated with the onset and progression of Parkinson’s disease. It synthesizes evidence supporting a possible bottom-up disease model while highlighting integrative, gut-targeted strategies as adjuncts to symptom management rather than proven disease-modifying therapies.

27 Jan 2026

New research initiative aims to develop retinal screening tool for Alzheimer's

The human eye may literally become a window revealing the earliest signals of Alzheimer's disease, thanks to a new federally funded research initiative at Oregon Health & Science University.

27 Jan 2026

UVA Data Science researcher leads $4.7M project for AI-powered diabetes management

University of Virginia School of Data Science researcher Heman Shakeri has been awarded a major new research grant to lead work at the intersection of machine learning and diabetes care.

27 Jan 2026

Pancreatic and 'skinny fat' linked to brain health risks

The effect of obesity on brain health may depend not only on how much fat is in the body, but also on the areas of the body where fat is stored, according to a study published today in Radiology, the flagship journal of the Radiological Society of North America (RSNA).

27 Jan 2026

Brain organoids reveal glioblastoma's secrets and therapy resistance

UCLA scientists have developed advanced miniature 3D tumor organoid models that make it possible to study glioblastoma tumors in a setting that closely mirrors the human brain, shedding light on how the aggressive cancer interacts with surrounding brain cells and the immune system to become more invasive and resistant to therapy.

27 Jan 2026

Cardiac MRI shows promise as a diagnostic tool for coronary heart disease

Cardiac magnetic resonance imaging (MRI) is an appropriate non-invasive procedure for functional diagnostics in patients who, as a result of basic diagnostics, are suspected of having chronic coronary heart disease (CHD) or progression of known CHD: The diagnostic accuracy of cardiac MRI is at least comparable to that of SPECT (single photon emission computed tomography) in the detection of CHD, but does not expose patients to radiation.

27 Jan 2026

BU receives $2M grant to study MedRhythms' MOVIVE device for Parkinson's gait

Boston University (BU) today announced it has been awarded a $2 million research grant from The Michael J. Fox Foundation for Parkinson's Research (MJFF).

27 Jan 2026

Prognostic nutritional index proposed as prognostic marker in hepatocellular carcinoma

The prognostic nutritional index (PNI), calculated from serum albumin and lymphocyte count, reflects a patient's immune-nutritional status and has been proposed as a prognostic marker in hepatocellular carcinoma (HCC).

27 Jan 2026

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Medical Condition News

Transcranial magnetic stimulation can be a cost-effective treatment option for depression

Silencing a specific brain circuit can prevent and reverse chronic pain

Study isolates mania-specific genetic architecture in bipolar disorder

Sleeping without pillows may help reduce nighttime eye pressure in glaucoma

Clinical trial aims to improve survival for patients with recurrent head and neck cancer

First topical CRISPR gene therapy corrects disease-causing mutations in human skin

Antibody-producing plasma cells shape effectiveness of PD-1 immunotherapy

Overactive protein cleanup disrupts nuclear pores in neurodegenerative disease

Immune system dysfunction may fuel progressive heart failure after heart attacks

MRI measures of glymphatic activity may improve noninvasive intracranial hypertension diagnosis

Study reveals heart, brain, neuroimmune connections driving damage after heart attacks

Insilico Medicine and Qilu Pharmaceutical partner to develop AI-designed cardiometabolic drugs

Gut problems may shape Parkinson’s disease progression through the gut-brain axis

New research initiative aims to develop retinal screening tool for Alzheimer's

UVA Data Science researcher leads $4.7M project for AI-powered diabetes management

Pancreatic and 'skinny fat' linked to brain health risks

Brain organoids reveal glioblastoma's secrets and therapy resistance

Cardiac MRI shows promise as a diagnostic tool for coronary heart disease

BU receives $2M grant to study MedRhythms' MOVIVE device for Parkinson's gait

Prognostic nutritional index proposed as prognostic marker in hepatocellular carcinoma

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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