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$Assessing clinical benefit and safety in trial waivers for treatment-refractory cancers$

Assessing clinical benefit and safety in trial waivers for treatment-refractory cancers

Patients with treatment-refractory cancers who received eligibility and testing waivers to participate in a large basket/umbrella oncology trial had similar rates of clinical benefit and adverse events as patients who participated in the trial without waivers.

27 Jun 2024

Discovery of nanoparticle-based drug delivery system could revolutionize schizophrenia treatment

Schizophrenia is a complicated mental health disorder accompanied by wide range of symptoms such as hallucinations, impaired cognitive ability, and disorganized speech or behavior.

27 Jun 2024

Uptick in early-onset gastrointestinal cancers raises the need for better prevention and diagnosis

Treatment of gastrointestinal (GI) cancers is catching up with other areas of oncology and offering patients better prospects for survival and quality of life, but a significant uptick in early-onset cases is raising new questions about effective prevention, diagnosis and treatment.

27 Jun 2024

AI breakthrough: Speech analysis predicts Alzheimer's progression with 78.5% accuracy

A method for predicting Alzheimer’s disease (AD) progression.

27 Jun 2024

Diabetes decoded: How your gut microbiome influences disease risk

How microbial features and functions specific to subspecies and strains contribute to the pathological mechanisms of type 2 diabetes.

27 Jun 2024

Cell division's hidden safety mechanism may influence cancer growth

Before a cell commits fully to the process of dividing itself into two new cells, it may ensure the appropriateness of its commitment by staying for many hours-;sometimes more than a day-;in a reversible intermediate state, according to a discovery by researchers at Weill Cornell Medicine. Their revelation of this fundamental feature of biology includes details of its mechanisms and dynamics, which may inform the development of future therapies targeting cancers and other diseases.

27 Jun 2024

UBC researchers use AI to improve endometrial cancer diagnosis and treatment

A discovery by researchers at the University of British Columbia promises to improve care for patients with endometrial cancer, the most common gynecologic malignancy.

27 Jun 2024

Evaluating CGM accuracy and benefits in non-diabetic populations

A new narrative review led by researchers at UCL and Birmingham Children's Hospital has found there is a lack of evidence to demonstrate the effective use of continuous glucose monitors (CGMs) in people not living with diabetes (PNLD).

27 Jun 2024

New study links COVID-19 to lasting neuropsychiatric issues, highlights vaccination benefits

COVID-19 survivors face significantly higher risks of developing neuropsychiatric conditions, but vaccination reduces these risks over time.

27 Jun 2024

Study reveals exercise and GLP-1 RA combination preserves bone health during weight loss

Combining exercise with GLP-1 RA liraglutide results in significant weight loss while preserving bone health in adults with obesity.

27 Jun 2024

Study finds lower cancer risk with alcohol abstinence and rehabilitation

A new study conducted by the Centre for Addiction and Mental Health (CAMH), Bordeaux University Hospital, France, and the World Health Organization (WHO) has found that individuals with alcohol dependence who undergo rehabilitation or maintain abstinence experience significantly lower risks of developing alcohol-associated cancers.

26 Jun 2024

Experts call for better information and treatments for post-orgasmic illness syndrome

A study in the "International Journal of Impotence Research" reveals that sexual medicine experts find current information on post-orgasmic illness syndrome (POIS) inadequate, often referring patients for psychotherapy or prescribing antihistamines with limited symptom improvement.

26 Jun 2024

UCL researchers highlight the growing role of cardiovascular health in dementia risk

Dementia risk factors associated with cardiovascular health may have increased over time compared to factors such as smoking and having less education, finds a new study led by UCL researchers.

26 Jun 2024

Rapeseed diacylglycerol oil may combat obesity by enhancing lipid metabolism

A study in "Nutrients" explores how rapeseed diacylglycerol oil (RDG) affects fat accumulation and metabolism in obese mice, showing significant benefits in reducing obesity-related indices and improving lipid metabolism.

26 Jun 2024

Nearly one third of adults worldwide failing to meet physical activity recommendations

New data show that nearly one third (31%) of adults worldwide, approximately 1.8 billion people, did not meet the recommended levels of physical activity in 2022.

26 Jun 2024

NIAID scientists discover probiotic treatment for eczema

NIAID research has led to the availability of a new over-the-counter topical eczema probiotic.

26 Jun 2024

Plant-based meat substitutes show promise for heart health

Even though there is substantial variability in the contents and nutritional profiles of plant-based meat alternatives (PBMAs), the nutritional profiles tend to reflect a heart-healthy dietary pattern.

26 Jun 2024

Moderate physical activity may be linked to reduced risk of ALS later in life

Moderate levels of physical activity and fitness may be linked to a reduced risk of amyotrophic lateral sclerosis (ALS) later in life, according to a new study published in the June 26, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

26 Jun 2024

Atogepant may decrease the risk of developing rebound headache in people with migraine

A drug used to prevent migraine may also be effective in people with migraine who experience rebound headaches, according to a new study published in the June 26, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

26 Jun 2024

Adaptive therapy approach can reduce toxicity and drug resistance in ovarian cancer

Ovarian cancer, often diagnosed at an advanced stage, presents significant treatment challenges because patients tend to develop resistance to conventional therapies quickly.

26 Jun 2024

Medical Condition News

Assessing clinical benefit and safety in trial waivers for treatment-refractory cancers

Discovery of nanoparticle-based drug delivery system could revolutionize schizophrenia treatment

Uptick in early-onset gastrointestinal cancers raises the need for better prevention and diagnosis

AI breakthrough: Speech analysis predicts Alzheimer's progression with 78.5% accuracy

Diabetes decoded: How your gut microbiome influences disease risk

Cell division's hidden safety mechanism may influence cancer growth

UBC researchers use AI to improve endometrial cancer diagnosis and treatment

Evaluating CGM accuracy and benefits in non-diabetic populations

New study links COVID-19 to lasting neuropsychiatric issues, highlights vaccination benefits

Study reveals exercise and GLP-1 RA combination preserves bone health during weight loss

Study finds lower cancer risk with alcohol abstinence and rehabilitation

Experts call for better information and treatments for post-orgasmic illness syndrome

UCL researchers highlight the growing role of cardiovascular health in dementia risk

Rapeseed diacylglycerol oil may combat obesity by enhancing lipid metabolism

Nearly one third of adults worldwide failing to meet physical activity recommendations

NIAID scientists discover probiotic treatment for eczema

Plant-based meat substitutes show promise for heart health

Moderate physical activity may be linked to reduced risk of ALS later in life

Atogepant may decrease the risk of developing rebound headache in people with migraine

Adaptive therapy approach can reduce toxicity and drug resistance in ovarian cancer

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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