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RENEW system utilizes machine learning for rare disease diagnosis

At Mayo Clinic, the mission to solve the unsolvable is at the heart of every rare disease case. Each diagnosis is a testament to perseverance, innovation and the relentless pursuit of answers.

25 Jun 2024

New enzyme targets hold promise for cancer therapies

Researchers at Baylor College of Medicine and collaborating institutions have uncovered new potential therapeutic targets for cancer and new insights into existing cancer drug targets, expanding the breadth of possibilities for treating this disease. Using a comprehensive approach that included integrating proteomics, genomics and epigenomics data from 10 cancer types, the team identified protein and small protein or peptide targets in cancer tissues and validated many of them experimentally as promising candidates for therapeutic strategies. The study appeared in Cell.

25 Jun 2024

Teleneurology offers solution to neurologist shortage

One of the first studies to examine patient acceptability of teleneurology and determine factors influencing acceptability across neurological conditions, has found teleneurology was highly acceptable across the full range of patients with different neurological diagnoses, including headache, movement disorders and other neurological symptoms and diagnoses. The study also determined that the more medical complexity -- having additional diseases -- was associated with increased patient satisfaction with teleneurology.

25 Jun 2024

Global food collapse looms amid heat and water stress, warns new study

By 2050, global food production could decline by up to 14% due to heat and water stress, leading to 1.36 billion more people experiencing severe food insecurity, highlighting the urgent need for climate change mitigation.

25 Jun 2024

UCL research reveals anxiety as a major risk factor for Parkinson's

The risk of developing Parkinson's is at least twice as high in people with anxiety compared to those without, finds a new study by UCL researchers.

24 Jun 2024

WEHI study reveals new methods in detecting necroptosis

Fully automated diagnostic techniques, including liquid handling robots, are poised to improve the lives of millions of people living with inflammatory diseases worldwide.

24 Jun 2024

Chronic loneliness linked to increased stroke risk in older adults

Chronic loneliness may significantly raise older adults' risk of stroke, according to a new study led by Harvard T.H. Chan School of Public Health.

24 Jun 2024

Enhancing adoptive T-cell therapy with nanowire innovation

Adoptive T-cell therapy has revolutionized medicine. A patient's T-cells -; a type of white blood cell that is part of the body's immune system -; are extracted and modified in a lab and then infused back into the body, to seek and destroy infection, or cancer cells.

24 Jun 2024

Study reveals cannabis and tobacco users face higher COVID-19 hospitalization and adverse outcomes

Researchers found that cannabis and tobacco use significantly increase the risk of hospitalization and adverse outcomes in COVID-19 patients, even when controlling for other factors.

24 Jun 2024

New study in rhesus macaques offers early intervention window for Alzheimer's

Research in nonhuman primates is opening the possibility of testing treatments for the early stages of Alzheimer's and similar diseases, before extensive brain cell death and dementia set in.

24 Jun 2024

Study reveals high rates of aspirin use for CVD prevention among older adults

A survey representing about 150 million adults annually suggests that aspirin use for primary prevention of cardiovascular disease (CVD) remains prevalent among older adults, contrary to recommendations from the American College of Cardiology and the American Heart Association.

24 Jun 2024

New ketamine slow-release tablet shows promise in treating severe depression

A new tablet form of ketamine has shown promise in treating severe depression, offering a potential alternative to existing clinic-based treatments that can be expensive and lacking in convenience for some patients.

24 Jun 2024

Family history of mental health disorders linked to developmental outcomes in siblings of autistic children

Researchers studied the impact of family history of neurodevelopmental and neuropsychiatric disorders on developmental outcomes in siblings of children with autism, highlighting significant associations with various phenotypic traits.

24 Jun 2024

Bridging knowledge and confidence to increase skin self-examinations

It's summer and time to enjoy the sunshine. But it's also important to do so safely. Skin cancer is the most common form of cancer in the United States-;and it's most commonly caused by sun exposure.

24 Jun 2024

Ketamine tablets offer new hope for treatment-resistant depression

For those suffering from treatment-resistant depression, the anaesthetic drug ketamine offers hope, but it has side effects and can be costly to access – a University of Otago-led clinical trial may change that.

24 Jun 2024

“Induced” learning and implementation of AHA/ASA best practices speed up stroke care

West Virginia University research illustrates that American Heart Association and American Stroke Association guidelines are effective at speeding up hospitals' response times for stroke treatment and can be mastered even by members of "ad hoc" medical teams that assemble rapidly on the fly.

24 Jun 2024

New study reveals the therapeutic potential of ZED1227 in celiac disease

A recent study led by researchers at Tampere University investigated whether a transglutaminase 2 inhibitor has potential as a drug to treat celiac disease.

24 Jun 2024

Researchers win $2.78 million grant to harness AI for precision treatment in rectal cancer

With a new five-year, $2.78 million grant from the National Institutes of Health and National Cancer Institute, researchers at Case Western Reserve University(CWRU), Cleveland Clinic and University Hospitals (UH) will use artificial intelligence (AI) to better treat rectal cancer patients.

24 Jun 2024

CARMEN: A tabletop robot to help people with mild cognitive impairment

Meet CARMEN, short for Cognitively Assistive Robot for Motivation and Neurorehabilitation–a small, tabletop robot designed to help people with mild cognitive impairment (MCI) learn skills to improve memory, attention, and executive functioning at home.

24 Jun 2024