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Aerobic exercise boosts cognitive function in women undergoing chemotherapy

Many women who receive chemotherapy experience a decreased ability to remember, concentrate, and/or think—commonly referred to as “chemo-brain” or “brain fog”—both short- and long-term. In a recent clinical trial of women initiating chemotherapy for breast cancer, those who simultaneously started an aerobic exercise program self-reported greater improvements in cognitive function and quality of life compared with those receiving standard care. The findings are published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society.

26 Oct 2024

Ipsen's elafibranor recommended for use in patients with rare liver disease

Ipsen announced today that the National Institute for Health and Care Excellence (NICE) has recommended elafibranor 80mg tablets for the treatment of PBC in combination with ursodeoxycholic acid (UDCA) in adults with an inadequate response to UDCA, or as monotherapy in adults unable to tolerate UDCA. This makes elafibranor the first medicine for PBC approved for use on the NHS in nearly a decade.

26 Oct 2024

MHRA greenlights donanemab for early stage Alzheimer’s disease

The Medicines and Healthcare products Regulatory Agency (MHRA) has today, 23 October 2024, approved a license for the medicine donanemab (Kisunla) for use in the early stages of Alzheimer’s disease, following a thorough review of the benefits and risks.

26 Oct 2024

Pioneering trial to test multiple new treatments for glioblastoma

A pioneering research study announced today (October 23) will trial multiple new treatments for people in the UK living with glioblastoma, an aggressive form of brain cancer.

26 Oct 2024

New research trial aims to address a disabling post-stroke condition

A major new research trial led by academics at the University of East Anglia (UEA) and taking place at eight major stroke centres across England, will test the efficacy of a new therapy for a disabling post-stroke condition that affects around one in three survivors, thanks to a £1.26m grant from the Efficacy and Mechanism Evaluation (EME) Programme - a partnership between the National Institute for Health and Care Research (NIHR) and the Medical Research Council (MRC).

26 Oct 2024

Patient Claim Line outlines key signs of stroke and how to reduce risks

Every five minutes, someone in the UK will experience a stroke, with 1.3 million people in the country having survived a stroke. The condition can be both life-threatening and life-altering, so knowing what to look out for and how to act in the event of a stroke is essential.

26 Oct 2024

Surge in GLP-1 drug use for obesity coincides with drop in bariatric surgery

Researchers from Mass General Brigham and collaborators found that use of GLP-1 drugs to treat obesity more than doubled from 2022 to 2023 while rates of surgery dropped by one quarter.

26 Oct 2024

Study links masculine norms to poor cardiovascular health awareness

Cardiovascular disease remains a top cause of sickness and death in the U.S. and worldwide. Doctors and researchers have it especially high on their radar because it's more modifiable and preventable than many other diseases and causes of death.

26 Oct 2024

New lung cancer screening initiative targets disparities in Central Texas

A new lung cancer screening initiative has made significant strides in overcoming barriers to care for low-income, uninsured and minority populations in Central Texas -; a critical step toward reducing disparities in lung cancer outcomes.

26 Oct 2024

Taurine supplementation linked to reduced atherosclerotic plaque development

Previous studies suggest that taurine supplementation may attenuate atherosclerosis by reducing lipid levels. However, energy drinks containing taurine have been shown to increase blood pressure, a key risk factor for atherosclerosis. Thus, the role of taurine in atherosclerosis remains controversial.

26 Oct 2024

Discovery of stem-like CD4 T cells offers new hope for cancer immunotherapy

Researchers at Winship Cancer Institute of Emory University have identified a novel type of immune cell, called the stem-like CD4 T cell, that plays a pivotal role in anti-tumor immunity.

26 Oct 2024

Extracellular vesicles play key role in cancer drug resistance

Despite significant advancements in cancer treatment, drug resistance remains a persistent challenge. Cancer cells can often develop resistance to treatments such as chemotherapy, radiotherapy, and immunotherapy, leading to reduced treatment efficacy.

25 Oct 2024

Study: High prevalence of depression found among people living with HIV in Nigeria

Depression can lead to poor outcomes during antiretroviral therapy, and current evidence suggests high rates of depression among people living with human immunodeficiency virus (PLHIV), especially in low-and middle-income countries.

25 Oct 2024

Elite ice hockey players with concussion history have heightened mental health symptoms

Elite ice hockey players with a history of concussion report heightened mental health symptoms, according to a new study from Lund University in Sweden. In addition, one in five female hockey players suffered symptoms of burnout, and both sexes reported an alcohol consumption at a risk-level.

25 Oct 2024

Evaluating the effectiveness of GAAD for early detection of hepatocellular carcinoma

Early detection of hepatocellular carcinoma (HCC) is crucial for improving survival in patients with chronic hepatitis.

25 Oct 2024

Advanced fibrosis linked to liver complications in biopsy-proven MASLD

Data regarding risk factors and long-term outcomes of U.S. patients with biopsy-proven metabolic dysfunction-associated steatotic liver disease (MASLD) are limited.

25 Oct 2024

UCLA researchers identify key protein in heart healing after attack

UCLA scientists have identified the protein GPNMB as a critical regulator in the heart's healing process after a heart attack.

25 Oct 2024

Tertiary lymphoid structures linked to improved outcomes in liver cancer patients

A newly described stage of a lymph node-like structure seen in liver tumors after presurgical immunotherapy may be vital to successfully treating patients with hepatocellular carcinoma, according to a study by researchers from the Johns Hopkins Kimmel Cancer Center.

25 Oct 2024

RNA modifications and their role in cancer development

Cancer, a disease with global impact, is intricately linked to dysregulated gene expression, which is influenced by both genetic mutations and epigenetic changes, including RNA modifications.

25 Oct 2024