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Advanced fibrosis linked to liver complications in biopsy-proven MASLD

Data regarding risk factors and long-term outcomes of U.S. patients with biopsy-proven metabolic dysfunction-associated steatotic liver disease (MASLD) are limited.

25 Oct 2024

UCLA researchers identify key protein in heart healing after attack

UCLA scientists have identified the protein GPNMB as a critical regulator in the heart's healing process after a heart attack.

25 Oct 2024

Tertiary lymphoid structures linked to improved outcomes in liver cancer patients

A newly described stage of a lymph node-like structure seen in liver tumors after presurgical immunotherapy may be vital to successfully treating patients with hepatocellular carcinoma, according to a study by researchers from the Johns Hopkins Kimmel Cancer Center.

25 Oct 2024

RNA modifications and their role in cancer development

Cancer, a disease with global impact, is intricately linked to dysregulated gene expression, which is influenced by both genetic mutations and epigenetic changes, including RNA modifications.

25 Oct 2024

New plasma treatment shows promise for healing rotator cuff injuries

The human body, filled with muscles and moving parts, is far from indestructible. Injuries are common, especially where tendons and bones connect.

25 Oct 2024

New insights into rejection entities in kidney transplantation

Investigators recently uncovered key insights into newly defined rejection entities in kidney transplantation that may offer improved patient risk categorization post-transplant. The research will be presented at ASN Kidney Week 2024 October 23– 27.

25 Oct 2024

ClinGen publishes data on over 2700 genes relevant to genetic diseases

The Clinical Genome Resource (ClinGen), a National Institutes of Health (NIH)-funded resource that works to define the clinical relevance of genes and variants, has published data on more than 2,700 genes curated for relevance to genetic diseases, including cancer, cardiovascular disease and neurodevelopmental disorders.

25 Oct 2024

Review highlights advances in flexible optoelectronics for cardiac healthcare

A review paper by scientists at Institute of Chemistry, Chinese Academy of Sciences summarized the progress of biointegrated flexible and stretchable optoelectronics for wearable and implantable cardiac healthcare.

25 Oct 2024

New AI tool revolutionizes detection of rare gastrointestinal diseases

Researchers from LMU, TU Berlin, and Charité have developed a new AI tool that uses imaging data to also detect less frequent diseases of the gastrointestinal tract.

25 Oct 2024

Persistent activation of DNA damage response in the liver after MASLD reversal

Metabolic dysfunction-associated steatotic liver disease (MASLD) and its more advanced form, metabolic dysfunction-associated steatohepatitis, have emerged as the most prevalent liver diseases worldwide.

25 Oct 2024

Climate change impacts pollen patterns and allergy sensitization in Chicago

People have heard for years that climate change is having a significant impact on plant vegetation patterns and influencing how pollen and mold produce.

25 Oct 2024

Single treatment with CRISPR gene editing therapy offers hope for hereditary angioedema patients

A single treatment with, a CRISPR-Cas9 based gene editing therapy, is enough to replace the daily medication of patients with hereditary angioedema (HAE), a condition characterized by severe, painful and sudden onset of swelling, sometimes resulting in death.

25 Oct 2024