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Lin28/let-7 pathway plays an unexpected key role in type 2 diabetes

A pathway activated in cancer plays an unexpected key role in metabolic diseases like type 2 diabetes, according to a study by researchers at Children's Hospital Boston. Evidence that the Lin28/let-7 pathway influences the cellular response to glucose provides a unifying theme to perplexing data that associates human genetic variation with diabetes risk.

30 Sep 2011

Review of stroke treatment could save lives

Doctors are underutilising crucial medication to prevent deadly strokes in those with a common type of heart condition, new research says, leading to fresh calls for a review of current treatment strategies and more research into stroke prevention.

29 Sep 2011

Almirall seeks European approval for linaclotide to treat irritable bowel syndrome with constipation

Almirall, S.A. announced today that it has submitted a Marketing Authorisation Application (MAA) to the European Medicines Agency (EMA) for linaclotide, an investigational guanylate cyclase-C (GC-C) receptor agonist for the treatment of irritable bowel syndrome with constipation (IBS-C). Once approved, linaclotide will be marketed in Europe under the trademark Constella®.

29 Sep 2011

Single hallucinogen dose creates personality change lasting for a year

A single high dose of the hallucinogen psilocybin, the active ingredient in so-called "magic mushrooms," was enough to bring about a measureable personality change lasting at least a year in nearly 60 percent of the 51 participants in a new study, according to the Johns Hopkins researchers who conducted it.

29 Sep 2011

Tobacco companies deliberately kept findings of cancer-causing radioactive particles from the public

Tobacco companies knew that cigarette smoke contained radioactive alpha particles for more than four decades and developed "deep and intimate" knowledge of these particles' cancer-causing potential, but they deliberately kept their findings from the public, according to a new study by UCLA researchers.

29 Sep 2011

Plausible way to circumvent drug resistance in breast cancer cells

Breast cancer cells that mutate to resist drug treatment survive by establishing tiny pumps on their surface that reject the drugs as they penetrate the cell membrane - making the cancer insensitive to chemotherapy drugs even after repeated use.

29 Sep 2011

Researchers reveal how motivation facilitates motor functional recovery in stroke, SCI patients

An effective recovery has been observed in stroke patients and those with spinal cord injuries who have strong vitality and motivation to rehabilitate in clinical practice. However, it was not really clear how motivation facilitates functional recovery in brain science.

29 Sep 2011

Intensive blood glucose control therapy provides no added benefit against cognitive decline in older diabetics

Intensive control of blood sugar levels beyond standard targets provides no additional protection against cognitive decline in older people with diabetes than standard treatment, according to a national study coordinated by researchers at Wake Forest Baptist Medical Center.

29 Sep 2011

Drinking habits of romantic partner's friends impact adolescent's future drinking behaviors

The drinking habits of a romantic partner's friends are more likely to impact an adolescent's future drinking than are the behaviors of an adolescent's own friends or significant other, according to a new study in the October issue of the American Sociological Review.

29 Sep 2011

Large-scale study on cat intestinal cancer could ultimately benefit humans

A recent, large-scale study on cat intestinal cancer has provided new insight into a common pet disease and its causes; the findings could ultimately benefit humans.

29 Sep 2011

Positive new data from Otonomy's OTO-104 Phase 1b study on Meniere's disease

Otonomy, Inc., a clinical stage biopharmaceutical company developing innovative therapeutics for diseases and disorders of the inner and middle ear, today announced that researchers presented positive new data from a Phase 1b study of the company's lead product candidate, OTO-104, in patients with Meniere's disease.

29 Sep 2011

VHI releases report on HMO quality and satisfaction

Open enrollment is fast approaching for thousands of HMO members in Virginia. Every year during this period, members have the option of selecting a health plan by comparing plan benefits and monthly premiums for the upcoming year.

29 Sep 2011

DSMB authorizes ACT to proceed with next set of patients in stem cell clinical trials

Advanced Cell Technology, Inc., a leader in the field of regenerative medicine, announced today that the independent Data and Safety Monitoring Board (DSMB) overseeing the Company's two ongoing stem cell clinical trials in the United States authorized ACT to move forward with enrolling and treating the next set of patients in each of the trials.

29 Sep 2011

UCSF scientists identify how normal cells transform into brain tumors

Brain tumor specimens taken from neurosurgery cases at the University of California, San Francisco (UCSF) Medical Center has given scientists a new window on the transformation that occurs as healthy brain cells begin to form tumors.

29 Sep 2011

Gallup, Healthways reveal new data on chronic disease burden of UK

Gallup, the global polling organization, and Healthways, the worldwide leader in well-being improvement, today jointly revealed new data showing that chronic conditions, such as obesity, diabetes and cancer are costing the UK economy 21.6 billion pounds a year in lost productivity.

29 Sep 2011

Heavy smoking linked with chronic musculoskeletal pain in women

Kentucky women who smoke heavily may experience more chronic musculoskeletal pain, suggests a new study led by University of Kentucky researchers.

29 Sep 2011

Three papers reveal structure and workings of G protein-coupled receptors

Three international teams of scientists, led by researchers at the University of California San Diego, University of Michigan and Stanford University, have published a trio of papers describing in unprecedented detail the structure and workings of G protein-coupled receptors (GPCRs), a large family of human proteins that are the target of one-third to one-half of modern drugs.

29 Sep 2011

Medical Condition News

Lin28/let-7 pathway plays an unexpected key role in type 2 diabetes

Review of stroke treatment could save lives

Almirall seeks European approval for linaclotide to treat irritable bowel syndrome with constipation

Single hallucinogen dose creates personality change lasting for a year

Tobacco companies deliberately kept findings of cancer-causing radioactive particles from the public

Plausible way to circumvent drug resistance in breast cancer cells

Researchers reveal how motivation facilitates motor functional recovery in stroke, SCI patients

Intensive blood glucose control therapy provides no added benefit against cognitive decline in older diabetics

Drinking habits of romantic partner's friends impact adolescent's future drinking behaviors

Large-scale study on cat intestinal cancer could ultimately benefit humans

Positive new data from Otonomy's OTO-104 Phase 1b study on Meniere's disease

VHI releases report on HMO quality and satisfaction

DSMB authorizes ACT to proceed with next set of patients in stem cell clinical trials

UCSF scientists identify how normal cells transform into brain tumors

Gallup, Healthways reveal new data on chronic disease burden of UK

Heavy smoking linked with chronic musculoskeletal pain in women

Three papers reveal structure and workings of G protein-coupled receptors

ACRO releases statement on World Heart Day

Low-tech, inexpensive interventions for bedsores could benefit long-term care residents

Genetic variant may increase severity of coronary artery disease in patients with diabetes

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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