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Reverse integration and wheelchair athletes playing basketball

Wheelchair basketball: It's a fast, skillful game, dazzling to watch, gruelling to play. It's also a sport that in Canada has become one of the most inclusive, welcoming athletes with disability and able-bodied athletes alike to its leagues and teams. And athletes like it that way.

18 Jan 2012

New pathways in battle against obesity and other lifestyle diseases

The world is encountering an epidemic of obesity, heart disease and diabetes. In the west it is already widespread and it is now exploding in the developing world with the rapid change in the lifestyles of recent generations.

18 Jan 2012

Peter Munk Cardiac Centre doctors perform renal denervation in first Canadian patient

Doctors at the Peter Munk Cardiac Centre today performed a minimally invasive surgical procedure to treat high blood pressure, called renal denervation, for the first time in Canada. The procedure can significantly reduce high blood pressure in patients who cannot effectively treat their hypertension through drugs. These patients, numbering approximately 250,000 Canadians, have to endure an especially high risk of heart attacks and stroke, which continues to kill thousands of Canadians every year.

18 Jan 2012

Researchers identify critical cellular, molecular events that lead to esophageal adenocarcinoma

Researchers at Columbia University Medical Center (CUMC) have identified the critical early cellular and molecular events that give rise to a type of esophageal cancer called esophageal adenocarcinoma, the fastest-rising solid tumor in the United States.

18 Jan 2012

Defects in mitochondria lead to devastating neurodegenerative disease

A devastating neurodegenerative disease that first appears in toddlers just as they are beginning to walk has been traced to defects in mitochondria, the 'batteries' or energy-producing power plants of cells. This finding by a team of researchers, led by investigators from the Montreal Neurological Institute and Hospital - The Neuro- at McGill University, was published in this week's issue of the Proceedings of the National Academy of Sciences of the USA.

18 Jan 2012

Scientists identify pathway that activates hepsin on the surface of breast tumor cells

Scientists from the University of Helsinki and from UCSF have exposed a cell pathway that breast tumor cells use to destruct local tissue neighborhood. Cancer cells may use this pathway to free themselves from mammary epithelial tissue architecture, to spread to surrounding tissues. The cell pathway, the researchers found, is a biochemical chain of events leading to activation of a protein-cleaving enzyme on the surface of the tumor cells.

18 Jan 2012

Chan faces financing challenges in second term as WHO director-general

The expected re-appointment of Margaret Chan as the WHO's director-general "comes at a perilous moment for WHO," a Lancet editorial states.

18 Jan 2012

Researchers discover changes that cause tumor progression and metastasis

Researchers at the Centro de Gen-mica e Investigaci-n Oncol-gica (GENYO) -of which the University of Granada, Pfizer and the Andalusian Regional Government are members- have identified the genetic and phenotypic changes that cause tumor progression and metastasis.

18 Jan 2012

St. Baldrick's Foundation awards $47,000 to help kids with cancer

It takes life-saving research and access to clinical trials to help children with cancer. The St. Baldrick's Foundation, a volunteer-driven charity dedicated to raising money for childhood cancer research, awarded an infrastructure grant of $47,000 to the Biopathology Center (BPC), housed in The Research Institute at Nationwide Children's Hospital.

18 Jan 2012

Study examines effect of MELD score-based allocation on post-liver transplant kidney failure

Research from the University of Michigan Health System shows the risk for kidney failure among liver transplant recipients is higher following the implementation of Model of End Stage Liver Disease (MELD), a policy change in 2002 that altered how liver transplant allocation is decided.

18 Jan 2012

Bioengineers receive $2 million NIH grant to develop new toxicology tests

Chemicals in pharmaceutical drugs can obviously save lives. But as more and stronger chemicals have been introduced, our basic knowledge of the broader health impact of all these chemicals has not kept up with the rapid pace of innovation. There is exceptionally little information on how chemicals in our drugs and also in the environment around us, including on the food we eat, impact some of the most important cells in our body: stem cells. Without basic knowledge and tests on the impact of chemicals on our stem cells, we may be unwittingly damaging essential regenerative functions in our body.

18 Jan 2012

Ethanol, nonalcoholic compounds in red wine may reduce risk of vascular disease

Observational epidemiologic studies relating wine and alcohol to health all suffer from the fact that they, of necessity, compare people who prefer certain beverages, but not the beverages themselves. While there have been many intervention trials in animals, randomized trials in humans are less common. Randomized crossover trials, in which each subject receives all interventions in sequence, can be especially important as they tend to avoid baseline differences among subjects and can detect effects of different interventions with smaller numbers of subjects.

18 Jan 2012

PCORI to meet this week to release national priorities for medical effectiveness research

The Patient-Centered Outcomes Research Institute, an independent board established by the health law, will meet this week to set priorities for "comparative effectiveness research." In other news related to the health law, the News Hour reports on how the overahul has impacted pediatric cancer patients and the New York Times reports on the law's provisions related to screening kids for obesity and providing them counseling.

18 Jan 2012

Insights into rates and impact of mTBI among military personnel in Iraq/Afghanistan

As the last U.S. troops return home from Iraq, new research lends timely insights into the rates and impact of mild traumatic brain injury (mTBI) among military personnel serving in Iraq/Afghanistan, according to a topical issue of The Journal of Head Trauma Rehabilitation (JHTR), the official journal of the Brain Injury Association of America.

18 Jan 2012

WHO's Chan urges new approach to preventing, fighting diseases at Executive Board meeting

"Countries need to change their current mindset to successfully tackle non-communicable diseases (NCDs), the head of the United Nations World Health Organization (WHO) said Monday, adding that governments will need to explore new approaches to prevent and treat these diseases, which have quickly become one of the most pressing issues in public health," the U.N. News Centre reports.

18 Jan 2012

Alpha-1-antitrypsin may reduce effects of GVHD

A natural enzyme derived from human blood plasma showed potential in significantly reducing the effects of graft-vs.-host disease, a common and deadly side effect of lifesaving bone marrow transplants.

18 Jan 2012

New combination treatment more effective in treating cutaneous T-Cell lymphoma

Promising findings on a novel combination treatment approach for a chronic type of skin lymphoma are being published in JAMA's Archives of Dermatology by clinical researchers from Seidman Cancer Center at University Hospitals (UH) Case Medical Center and Case Western Reserve University School of Medicine.

18 Jan 2012

U.S. readies plan to fight Alzheimer's

The government is setting what it calls an ambitious goal for Alzheimer's disease: Development of effective ways to treat and prevent the mind-destroying illness by 2025. The Obama administration is developing the first National Alzheimer's Plan to find better treatments for the disease and offer better day-to-day care for those afflicted.

18 Jan 2012

Pfizer, Medivation report results from dimebon Phase 3 trial on AD

Medivation, Inc. and Pfizer Inc. today announced results from the CONCERT trial, which is a Phase 3 trial that evaluated dimebon (latrepirdine) when added to ongoing treatment with donepezil HCL tablets in patients with mild-to-moderate Alzheimer's disease.

18 Jan 2012

Scientists use gold-filled silicon wafers to target and burn breast cancer cells

By shining infrared light on specially designed, gold-filled silicon wafers, scientists at The Methodist Hospital Research Institute have successfully targeted and burned breast cancer cells. If the technology is shown to work in human clinical trials, it could provide patients a non-invasive alternative to surgical ablation, and could be used in conjunction with traditional cancer treatments, such as chemotherapy, to make those treatments more effective.

18 Jan 2012

Medical Condition News

Reverse integration and wheelchair athletes playing basketball

New pathways in battle against obesity and other lifestyle diseases

Peter Munk Cardiac Centre doctors perform renal denervation in first Canadian patient

Researchers identify critical cellular, molecular events that lead to esophageal adenocarcinoma

Defects in mitochondria lead to devastating neurodegenerative disease

Scientists identify pathway that activates hepsin on the surface of breast tumor cells

Chan faces financing challenges in second term as WHO director-general

Researchers discover changes that cause tumor progression and metastasis

St. Baldrick's Foundation awards $47,000 to help kids with cancer

Study examines effect of MELD score-based allocation on post-liver transplant kidney failure

Bioengineers receive $2 million NIH grant to develop new toxicology tests

Ethanol, nonalcoholic compounds in red wine may reduce risk of vascular disease

PCORI to meet this week to release national priorities for medical effectiveness research

Insights into rates and impact of mTBI among military personnel in Iraq/Afghanistan

WHO's Chan urges new approach to preventing, fighting diseases at Executive Board meeting

Alpha-1-antitrypsin may reduce effects of GVHD

New combination treatment more effective in treating cutaneous T-Cell lymphoma

U.S. readies plan to fight Alzheimer's

Pfizer, Medivation report results from dimebon Phase 3 trial on AD

Scientists use gold-filled silicon wafers to target and burn breast cancer cells

Making Complex Cell Culture Easy and Efficient with AI

This International Women’s Day, Meet the Scientist Changing Women’s Healthcare

Microphysiological systems in drug discovery

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