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Santarus commences SAN-300 Phase I clinical study to treat inflammatory diseases

Santarus, Inc., a specialty biopharmaceutical company, today announced that it has initiated a Phase I clinical study with SAN-300, its anti-VLA-1 antibody.

10 Mar 2011

Professor utilizes $300,000 N.Y. grant to study adult neural stem cells

Rensselaer Polytechnic Institute Assistant Professor of Biomedical Engineering Deanna Thompson is utilizing more than $300,000 in New York state funding as part of the state stem cell research program, NYSTEM, to study adult neural stem cells.

10 Mar 2011

Caspase inhibition can prevent brain inflammation in neurological diseases

Neurodegenerative diseases like Alzheimer's and Parkinson's are partly attributable to brain inflammation. Researchers at Karolinska Institutet now demonstrate in a paper published in Nature that a well-known family of enzymes can prevent the inflammation and thus constitute a potential target for drugs.

10 Mar 2011

St. Joseph's Hospital launches new neuromodulation center in Barrow

St. Joseph's Hospital and Medical Center's Barrow Neurological Institute has received a $10.1 million donation, the largest single gift in the organization's history and one of the biggest ever given to any Arizona hospital.

10 Mar 2011

Researcher launches new DBS clinical trial to pinpoint brain activity in depressed people

A top medical researcher at Barrow Neurological Institute at St. Joseph's Hospital in Phoenix, Arizona, has launched a clinical trial to pinpoint brain activity in depressed people by using scientifically designed sad and heartrending photos and music.

10 Mar 2011

First recording of cortically induced neural activity of basal ganglia in Parkinson's disease, dystonia during DBS

Movement disorders such as Parkinson's diseases and dystonia are caused by abnormal neural activity of the basal ganglia located deep in the brain. The basal ganglia are connected to the cerebral cortex in the brain surface through complex neural circuits.

10 Mar 2011

ALR commits funding for new study to identify lupus susceptibility genes in multiple ethnicities

The Alliance for Lupus Research (ALR) – the world's largest private funder of lupus research – today announced funding of an important new study to identify lupus susceptibility genes in multiple ethnicities including African Americans, who are three times more likely than Caucasians to have the disease.

10 Mar 2011

New study sheds 'light' on intricate brain cell connections responsible for anxiety

A new study sheds light--both literally and figuratively--on the intricate brain cell connections responsible for anxiety.

10 Mar 2011

U-M participates in national trial for alternative approach to open heart surgery for severe aortic stenosis

The University of Michigan Cardiovascular Center, a leader in heart valve replacement, will participate in a national clinical trial to offer patients a less invasive approach to replacing diseased aortic valves.

10 Mar 2011

CTI announces final pixantrone clinical trial design for treatment of DLBCL

Cell Therapeutics, Inc. today announced the final clinical trial design of a randomized pivotal trial of pixantrone for the treatment of diffuse large B-cell lymphoma following discussions with the U.S. Food and Drug Administration's Division of Hematologic Products.

10 Mar 2011

California leaders completes much-anticipated State Plan for Alzheimer's disease

Anticipating a catastrophic increase in Alzheimer's disease and related dementias, California leaders have completed the much-anticipated California State Plan for Alzheimer's disease, a disease estimated to double among Californians by the year 2030.

10 Mar 2011

CDH Proton Center expands treatment capacity

The CDH Proton Center, A ProCure Center, in suburban Chicago, is now able to treat a wider variety of cancer tumors with the opening of a treatment room with a gantry, a nearly 100-ton rotating steel wheel that allows the proton beam to be directed at the tumor from any angle.

10 Mar 2011

Experimental drug effectively shuts off MCL1 gene and induces apoptosis

Predictive Biomarker Sciences (PBS-Bio) has uncovered how the experimental drug UNBS1450, produced by Unibioscreen, kills cancer cells.

10 Mar 2011

Blood biomarker may help decide intake of aspirin or NSAIDs for reduction of cancer risk

The reduced risk of colorectal cancer associated with taking aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) may be confined to individuals already at risk because of elevations in a particular inflammatory factor in the blood.

10 Mar 2011

Novel sortase-based techniques allow modification of a large variety of different proteins

Whitehead Institute scientists have created a method that site-specifically modifies proteins to exert control over their properties when administered therapeutically. The technique should be useful to increase potency, slow metabolism, and improve thermal stability of therapeutically useful proteins, such as interferon alpha 2 (IFN-alpha 2), which is used to treat variety of diseases, including leukemia, melanoma, and chronic hepatitis C.

10 Mar 2011

Tiniest pollution particles can contribute to cardiovascular disease in diabetic people

Scientists are untangling how the tiniest pollution particles - which we take in with every breath we breathe - affect our health, making people more vulnerable to cardiovascular and respiratory problems.

10 Mar 2011

First disease-specific biomarker for sporadic Creutzfeldt-Jakob disease identified

Neena Singh, MD, PhD and colleagues at Case Western Reserve University School of Medicine have identified the first disease-specific biomarker for sporadic Creutzfeldt-Jakob disease (sCJD), a universally fatal, degenerative brain disease for which there is no cure. sCJD is one of the causes of dementia and typically leads to death within a year of disease onset.

10 Mar 2011

Need for new definition of 'normal' blood pressure

As many as 100 million Americans may currently be misclassified as having abnormal blood pressure, according to Dr. Brent Taylor from the Veterans Affairs Health Care System in Minneapolis and the University of Minnesota and his colleagues. Their findings show that these people are not actually more likely to die prematurely than those with 'normal' blood pressure, i.e. below 120/80.

10 Mar 2011

CRT, ICR sign deal with ZoBio to discover and develop cancer drugs

Cancer Research Technology and The Institute of Cancer Research have signed a deal with Dutch drug discovery company, ZoBio BV, to discover and develop drugs to block a DNA repair target which may play a role in cancer cell survival.

10 Mar 2011

Medtronic opens new manufacturing facility in Singapore

Medtronic, Inc., the global medical technology leader, announced today the official opening of its new manufacturing facility, Medtronic Singapore Operations. The facility will enhance the company's manufacturing capabilities to meet the future expected growth of cardiac devices in Asia.

10 Mar 2011

Medical Condition News

Santarus commences SAN-300 Phase I clinical study to treat inflammatory diseases

Professor utilizes $300,000 N.Y. grant to study adult neural stem cells

Caspase inhibition can prevent brain inflammation in neurological diseases

St. Joseph's Hospital launches new neuromodulation center in Barrow

Researcher launches new DBS clinical trial to pinpoint brain activity in depressed people

First recording of cortically induced neural activity of basal ganglia in Parkinson's disease, dystonia during DBS

ALR commits funding for new study to identify lupus susceptibility genes in multiple ethnicities

New study sheds 'light' on intricate brain cell connections responsible for anxiety

U-M participates in national trial for alternative approach to open heart surgery for severe aortic stenosis

CTI announces final pixantrone clinical trial design for treatment of DLBCL

California leaders completes much-anticipated State Plan for Alzheimer's disease

CDH Proton Center expands treatment capacity

Experimental drug effectively shuts off MCL1 gene and induces apoptosis

Blood biomarker may help decide intake of aspirin or NSAIDs for reduction of cancer risk

Novel sortase-based techniques allow modification of a large variety of different proteins

Tiniest pollution particles can contribute to cardiovascular disease in diabetic people

First disease-specific biomarker for sporadic Creutzfeldt-Jakob disease identified

Need for new definition of 'normal' blood pressure

CRT, ICR sign deal with ZoBio to discover and develop cancer drugs

Medtronic opens new manufacturing facility in Singapore

The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

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