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Ridaforolimus achieves primary endpoint in Phase 3 trial for metastatic soft-tissue and bone sarcomas

ARIAD Pharmaceuticals, Inc., today announced top-line data showing that ridaforolimus, an investigational oral mTOR inhibitor, met the primary endpoint of improved progression-free survival (PFS) compared to placebo in the Phase 3 SUCCEED trial conducted in patients with metastatic soft-tissue or bone sarcomas who previously had a favorable response to chemotherapy.

19 Jan 2011

Curcumin and dye brilliant blue G may help block dangerous swelling in TBI

An old Indian spice and a dye whose cousin makes sports drinks blue are pointing scientists toward better treatment of traumatic brain injuries.

19 Jan 2011

New study provides clear data on high rate of childhood maltreatment among deaf community

A new study at Rochester Institute of Technology indicates that the incidence of maltreatment, including neglect and physical and sexual abuse, is more than 25 percent higher among deaf and hard-of-hearing children than among hearing youths. The research also shows a direct correlation between childhood maltreatment and higher rates of negative cognition, depression and post-traumatic stress in adulthood.

19 Jan 2011

Alternative interventions do just as well as cognitive interventions for reducing 'senior moments'

Trying to stave off senior moments with memory drills and similar brain-boosting activities? A new evidence review suggests that these specific training regimes are not any better than simple conversations at improving memory in older adults.

19 Jan 2011

New long-term survival data from OPUS, CRYSTAL studies demonstrate strong tumor shrinkage of Erbitux

Merck Serono, a division of Merck KGaA, Darmstadt, Germany, today highlighted a further analysis of the large randomized Phase II OPUS study demonstrating an association between early tumor shrinkage and long-term median overall survival (OS) of more than 2 years for patients with KRAS wild-type metastatic colorectal cancer (mCRC) treated with Erbitux® (cetuximab) plus FOLFOX standard chemotherapy.

19 Jan 2011

New study provides insight into developing therapeutics for airway disease

Researchers from Duke University Medical Center have identified how nanoparticles from diesel exhaust damage lung airway cells, a finding that could lead to new therapies for people susceptible to airway disease.

19 Jan 2011

New patented technique offers unprecedented view of DNA damage

New technology providing the first view of DNA damage throughout the entire human genome developed by Cardiff University scientists could offer a valuable new insight into the development and treatment of conditions like cancer.

19 Jan 2011

African American patients who are susceptible to hypertension may benefit from storytelling: New study

Controlling blood pressure is not only a medical challenge, but a social one as well. Because patients are required to strictly adhere to a treatment plan that may include medication, dietary restrictions and regular doctor visits, the ideas of wellness and health are also powerful parts of the social reinforcement needed for behavioral change.

19 Jan 2011

Loyola offers new, nonsurgical treatment for Dupuytren's contracture

Loyola University Health System is among the first centers to offer a new, nonsurgical treatment for Dupuytren's contracture, a debilitating condition that curls fingers toward the palm.

19 Jan 2011

Deep brain stimulation stabilizes motor symptoms in Parkinson's disease over time

Parkinson's disease symptoms begin subtly and worsen as damage to certain brain cells continues. But an electrical stimulation device implanted deep in the brain and programmed remotely, along with medications, may provide some control of "motor symptoms" common to the disease, such as shaking, stiffness, and loss of muscle control.

19 Jan 2011

UAB study uses InQ system to evaluate effects of secondary injury components on brain cells

InQ Biosciences, a provider of innovative technologies for cell growth and research, today announced that a pre-commercial version of its InQ Cell Research System is being utilized in a University of Alabama at Birmingham study evaluating the effects of secondary injury components on brain cells.

19 Jan 2011

Loyola introduces wheelchair yoga program for hospitalized patients

"There is a growing body of evidence to support the use of yoga as a health and healing tool and a complement to standard medical interventions and therapy," said Dr. Walsh, assistant professor, Department of Psychiatry & Behavioral Neurosciences, Loyola University Chicago Stritch School of Medicine.

19 Jan 2011

Lower levels in plasma of biomarkers beta-amyloid 42/40 increase rate of cognitive decline

Older adults without dementia and with lower levels in plasma of the biomarkers beta-amyloid 42/40 (protein fragments) had an increased rate of cognitive decline over a period of 9 years, according to a study in the January 19 issue of JAMA. The researchers also found that this relationship was stronger among individuals with less education and lower levels of literacy.

19 Jan 2011

Study shows physical activity helps people with osteoarthritis to walk faster

When a traffic light at a busy intersection flashes the WALK sign, people with knee osteoarthritis worry they can't walk fast enough to make it across the street in time. New Northwestern Medicine research shows people with this common arthritis are more likely to walk fast enough if they lead physically active lives.

19 Jan 2011

RG7204 Phase III study shows significant survival benefit in patients with metastatic melanoma

Genentech, a member of the Roche Group, today announced that BRIM3, a Phase III clinical study of RG7204, met its co-primary endpoints showing a significant survival benefit in people with previously untreated BRAF V600 mutation-positive metastatic melanoma.

19 Jan 2011

New GORE VIABAHN Endoprosthesis is now available in Europe

W. L. Gore & Associates today announced the European availability of the GORE VIABAHN Endoprosthesis on a lower profile delivery system. The announcement came during the Leipzig Interventional Course in Germany, where European interventionalists gathered to discuss new approaches in treating patients suffering from peripheral artery disease.

19 Jan 2011

Neuroform EZ Stent System helps neurosurgeons to treat brain aneurysms

A new device to treat brain aneurysms with stents improves access to the blood vessels allowing endovascular neurosurgeons to offer the minimally invasive technique to patients with complex cases. Dr. Demetrius Lopes, an endovascular neurosurgeon at Rush University Medical Center, was the first in the U.S. to use the new delivery system, called the Neuroform EZ Stent System.

19 Jan 2011

Positive preliminary results from Soligenix's SGX202 in GARS model

Soligenix, Inc., a late-stage biopharmaceutical company, announced today promising preliminary results from a preclinical study of SGX202 in a canine gastrointestinal acute radiation syndrome model.

19 Jan 2011

Cancer cells brought back under normal control

Scientists at The University of Nottingham have brought cancer cells back under normal control — by reactivating their cancer suppressor genes. The discovery could form a powerful new technology platform for the treatment of cancer of the breast and other cancers.

19 Jan 2011

Molecular imaging procedure may detect beta-amyloid in brain, increase accuracy of AD diagnosis

Preliminary research suggests that use of a type of molecular imaging procedure may have the ability to detect the presence of beta-amyloid in the brains of individuals during life, a biomarker that is identified during autopsy to confirm a diagnosis of Alzheimer disease, according to a study in the January 19 issue of JAMA.

19 Jan 2011

Medical Condition News

Ridaforolimus achieves primary endpoint in Phase 3 trial for metastatic soft-tissue and bone sarcomas

Curcumin and dye brilliant blue G may help block dangerous swelling in TBI

New study provides clear data on high rate of childhood maltreatment among deaf community

Alternative interventions do just as well as cognitive interventions for reducing 'senior moments'

New long-term survival data from OPUS, CRYSTAL studies demonstrate strong tumor shrinkage of Erbitux

New study provides insight into developing therapeutics for airway disease

New patented technique offers unprecedented view of DNA damage

African American patients who are susceptible to hypertension may benefit from storytelling: New study

Loyola offers new, nonsurgical treatment for Dupuytren's contracture

Deep brain stimulation stabilizes motor symptoms in Parkinson's disease over time

UAB study uses InQ system to evaluate effects of secondary injury components on brain cells

Loyola introduces wheelchair yoga program for hospitalized patients

Lower levels in plasma of biomarkers beta-amyloid 42/40 increase rate of cognitive decline

Study shows physical activity helps people with osteoarthritis to walk faster

RG7204 Phase III study shows significant survival benefit in patients with metastatic melanoma

New GORE VIABAHN Endoprosthesis is now available in Europe

Neuroform EZ Stent System helps neurosurgeons to treat brain aneurysms

Positive preliminary results from Soligenix's SGX202 in GARS model

Cancer cells brought back under normal control

Molecular imaging procedure may detect beta-amyloid in brain, increase accuracy of AD diagnosis

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

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