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Positive results from PLX4032 Phase 3 Trial in patients with metastatic melanoma

Plexxikon today announced positive data from an interim analysis of the BRIM3 trial, a large multi-center Phase 3 clinical study of PLX4032 in patients with previously untreated metastatic melanoma with the BRAF mutation. Patients treated with PLX4032 had an improved overall survival compared to patients treated with dacarbazine, the current standard of care.

19 Jan 2011

Study: Brain's 'autopilot' network may aid in early diagnosis of Alzheimer's disease

Watching the brain's "autopilot" network in real time may help determine the onset of cognitive decline and potentially aid in making an early diagnosis of Alzheimer's disease, according to researchers at Duke University Medical Center.

19 Jan 2011

Magnetic maneuverable capsule safe and well-tolerated in the stomach

A study from researchers in Germany showed that magnetic maneuvering of a modified capsule endoscope in the stomach of healthy volunteers under clinical conditions is safe, well-tolerated, and technically feasible. Maneuverability of the capsule within the stomach was excellent and visualization of the gastric mucosa, the inner lining of the stomach, was satisfactory in the majority of subjects.

19 Jan 2011

Study may help develop novel ways to combat lipotoxic cardiomyopathy, related heart disease

A team led by Rolf Bodmer, Ph.D. at Sanford-Burnham Medical Research Institute recently unraveled an alternative pathway to lipotoxic cardiomyopathy in fruit flies - a genetic mechanism that occurs independently of a diet high in fat.

19 Jan 2011

New findings show reduced vitamin D absorption in patients with quiescent CD

Researchers from Boston University School of Medicine have for the first time shown that reduced vitamin D absorption in patients with quiescent Crohn's disease may be the cause for their increased risk for vitamin D deficiency.

19 Jan 2011

Uric acid levels linked to severe osteoarthritis

The amount of uric acid in one's joints may increase the likelihood of severe osteoarthritis, the most common form of arthritis worldwide, according to researchers at Duke University Medical Center.

19 Jan 2011

MicroRNA-29 molecule makes brain cells resistant to programmed cell death

Researchers at the University of North Carolina at Chapel Hill have discovered a molecule that can make brain cells resistant to programmed cell death or apoptosis.

19 Jan 2011

Research identifies childhood traumatic stress as potential risk factor for obesity in adulthood

Scientific studies often attribute obesity to poor nutrition and lack of activity, but recent research has identified childhood traumatic stress as a potential risk factor for obesity in adulthood.

19 Jan 2011

AMBR sensor measures growth and drug susceptibility of bacterial cells without use of microscope

With an invention that can be made from some of the same parts used in CD players, University of Michigan researchers have developed a way to measure the growth and drug susceptibility of individual bacterial cells without the use of a microscope.

19 Jan 2011

Time-lapse technique can show cellular-level changes within deep brain regions: Study

Changes within deep regions of the brain can now be visualized at the cellular level, based on research on mice, which was funded by the National Institutes of Health. Published Sunday in Nature Medicine, the study used a groundbreaking technique to explore cellular-level changes over a period of weeks within deep brain regions, providing a level of detail not possible with previously available methods.

19 Jan 2011

Study highlights lack of treatment for adolescents with severe mental disorders

A recent study by Merikangas and colleagues published in the January 2011 issue of the Journal of the American Academy of Child and Adolescent Psychiatry shows that only half of adolescents that are affected with severely impairing mental disorders ever receive treatment for their disorders.

19 Jan 2011

Study shows new cardio-pulmonary resuscitation technique increases long-term survival of patients

A study led by Dr. Tom P. Aufderheide, professor of emergency medicine at The Medical College of Wisconsin, shows an alternative method of cardio-pulmonary resuscitation increases long-term survival of patients.

19 Jan 2011

Medtronic recieves conditional approval from FDA to modify CoreValve U.S. Pivotal Clinical Trial

Medtronic, today announced it has received conditional approval from the U.S. Food and Drug Administration to modify its CoreValve U.S. Pivotal Clinical Trial.

19 Jan 2011

Severe asthma in early childhood may lead to premature loss of lung function during adolescence: Study

Severe asthma in early childhood may lead to premature loss of lung function during adolescence and more serious disease during adulthood, researchers at Emory University School of Medicine report. Early identification and treatment of children with severe asthma is important to help stem asthma progression.

19 Jan 2011

Study highlights utility of CDS for diagnosing major depression

In the last 2010 issue of Psychotherapy and Psychosomatics, a new scale for measuring depression in cardiac patients is presented. The Cardiac Depression Scale was initially developed specifically for cardiac patients. Its purpose is to allow measurement over the continuum between low-level depressive symptomatology and major depression.

19 Jan 2011

Celulas Genetica, EHRI enter joint venture to pursue testing of Rutherford Procedure using NASA bioreactor

Emerging Healthcare Solutions, announced today that it has entered into a joint venture agreement with its wholly owned subsidiary, Celulas Genetica, in order to pursue testing of the revolutionary Rutherford Procedure using a NASA bioreactor.

19 Jan 2011

Study elaborates relationship between obesity and MDD-R, long-term use of ADs

This study demonstrates that patients using antidepressants continuously, mostly serotonin-selective reuptake inhibitors, show significantly more overweight and obesity than those using them intermittently or not at all.

18 Jan 2011

Diabetes increases risk of death in breast cancer patients

Breast cancer patients are nearly 50 percent more likely to die of any cause if they also have diabetes, according to a comprehensive review of research conducted by Johns Hopkins physicians.

18 Jan 2011

Soy protein lowers total cholesterol and non-HDL: New study

Soy protein's ability to lower total and LDL cholesterol has been extensively studied, but the mechanism whereby soy protein lowers cholesterol remains unresolved. A new study published in the Journal of Clinical Lipidology last month shows that soy protein lowers total cholesterol and non-HDL cholesterol significantly more than milk protein in patients with moderately high cholesterol levels.

18 Jan 2011

PAM50 test is now available to classify breast cancer subtypes

ARUP Laboratories, a leading national clinical and anatomic pathology reference laboratory and a leader in innovative laboratory research and development, today announced the availability of a new laboratory developed test designed to classify breast cancer into clinically significant molecular subtypes that are important for the management of the disease.

18 Jan 2011

Medical Condition News

Positive results from PLX4032 Phase 3 Trial in patients with metastatic melanoma

Study: Brain's 'autopilot' network may aid in early diagnosis of Alzheimer's disease

Magnetic maneuverable capsule safe and well-tolerated in the stomach

Study may help develop novel ways to combat lipotoxic cardiomyopathy, related heart disease

New findings show reduced vitamin D absorption in patients with quiescent CD

Uric acid levels linked to severe osteoarthritis

MicroRNA-29 molecule makes brain cells resistant to programmed cell death

Research identifies childhood traumatic stress as potential risk factor for obesity in adulthood

AMBR sensor measures growth and drug susceptibility of bacterial cells without use of microscope

Time-lapse technique can show cellular-level changes within deep brain regions: Study

Study highlights lack of treatment for adolescents with severe mental disorders

Study shows new cardio-pulmonary resuscitation technique increases long-term survival of patients

Medtronic recieves conditional approval from FDA to modify CoreValve U.S. Pivotal Clinical Trial

Severe asthma in early childhood may lead to premature loss of lung function during adolescence: Study

Study highlights utility of CDS for diagnosing major depression

Celulas Genetica, EHRI enter joint venture to pursue testing of Rutherford Procedure using NASA bioreactor

Study elaborates relationship between obesity and MDD-R, long-term use of ADs

Diabetes increases risk of death in breast cancer patients

Soy protein lowers total cholesterol and non-HDL: New study

PAM50 test is now available to classify breast cancer subtypes

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

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