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Clinical Data closes sale of genetic, pharmacogenomic testing and biomarker development business

Clinical Data, Inc. today announced that the Company has closed the sale of its genetic and pharmacogenomic testing and biomarker development business to Transgenomic, Inc. for $15.5 million. The sale completes Clinical Data's transformation into a pharmaceutical company with a deep product pipeline, including two promising late-stage compounds, the most advanced of which is vilazodone, a new treatment in development for Major Depressive Disorder.

30 Dec 2010

Dosing initiated in combination Phase I study of palifosfamide with etoposide and cisplatin/carboplatin in SCLC

ZIOPHARM Oncology, Inc., announced today that the first patient has been dosed in a Phase I, single arm, dose escalation study at the Indiana University Cancer Center of intravenous (IV) palifosfamide (ZIO-201) in combination with etoposide (VP-16) and cisplatin/carboplatin (platinum) in the treatment of small cell lung cancer (SCLC) and other cancers.

29 Dec 2010

Positive results from OMS201 Phase 1/2 trial in patients undergoing urologic procedures

Omeros Corporation, a biopharmaceutical company committed to discovering, developing and commercializing products focused on inflammation and disorders of the central nervous system, today announced results from the Phase 1/2 clinical trial of OMS201, the Company's urological PharmacoSurgery™ product candidate.

29 Dec 2010

CFTR protein regulates inflammation and cell death in emphysema, chronic lung diseases

A team of Johns Hopkins Children's Center researchers has discovered that a protein involved in cystic fibrosis also regulates inflammation and cell death in emphysema and may be responsible for other chronic lung diseases.

29 Dec 2010

New study reports close association between obesity and fibromyalgia

Afflicting up to 5 percent of the U.S. population, mostly women, fibromyalgia is characterized by widespread pain and range of function problems. A new study in The Journal of Pain reports there is close association between obesity and disability in fibromyalgia patients.

29 Dec 2010

CEL-SCI initiates Multikine Phase III trail for head and neck cancer

CEL-SCI Corporation announced today that it has commenced its Phase III clinical trial for Multikine®, the Company's flagship immunotherapy. CEL-SCI has now completed all of the manufacturing and regulatory requirements to begin enrollment of the study.

29 Dec 2010

Epilepsy more common than earlier thought: Study

Epilepsy prevalence and incidence is greater than earlier thought in the United States. The latest study shows that one in every 26 people in the United States will develop epilepsy at some point in their life. Experts believe this new revelation calls for more attention and funding for the disease.

29 Dec 2010

Experimental device for obstructive sleep apnea

Obstructive sleep apnea, a dangerous sleep disorder that affects millions of Americans may have found a cure. The disease commonly manifested as snoring but leading to tremendous sleep deprivation can be severely debilitating. Sleep deprivation may lead to car crashes, accidents, high blood pressure, heart attack, stroke, and diabetes.

29 Dec 2010

Controlling the amount of adipose tissue is key to combat obesity

Obesity is seen as the great pandemia of the XXI century. Recent data point to more than a billion adults in the world suffering from overweight, of which 300 million are clinically obese. What is more, the rates of child obesity show a worrying increase, with more than 155 million children and adolescents being overweight, of which 40 million are clearly obese.

29 Dec 2010

Merck confirms plans for developing vernakalant drug for atrial fibrillation

Cardiome Pharma Corp. today announced that it has been advised by its partner, Merck, that the current review of vernakalant is complete, and that Merck has informed Cardiome of its next steps in clinical development for vernakalant beginning in 2011.

29 Dec 2010

New innovative program to identify and treat combat veterans suffering from PTSD

An innovative program to identify and treat combat veterans suffering from Post Traumatic Stress Disorder - but who have not sought treatment - has been started by U.S.VETS, the nation's largest nonprofit devoted to providing housing and other services to homeless and at-risk veterans.

29 Dec 2010

Florida Hospital, Sanford-Burnham and Takeda enter obesity research collaboration

Florida Hospital, Sanford-Burnham Medical Research Institute (Sanford-Burnham), and Takeda Pharmaceutical Company Limited (Takeda)(TSE: 4502), announced today that they have signed a research agreement to form a collaboration to discover and evaluate new therapeutic approaches to obesity, a growing worldwide health problem. The partnership aligns complementary strengths in biomedical research, clinical research and drug development to identify and validate obesity- related biomarkers and new peripheral molecular targets of mutual interest.

29 Dec 2010

Top weight-loss behaviors

Losing weight and saving money are the top New Year's resolutions expected to vex Americans this year, experts say.

29 Dec 2010

Researchers develop breath-analysis technology for rapid detection of biomarkers

Researchers have overcome a fundamental obstacle in developing breath-analysis technology to rapidly diagnose patients by detecting chemical compounds called "biomarkers" in a person's respiration in real time.

29 Dec 2010

Kennedy Krieger inagurates new clinic for AHO treatment and research

Kennedy Krieger Institute announced the opening of a new clinic for the treatment and research of Albright hereditary osteodystrophy (AHO), a rare genetic disorder affecting the bones, skin and hormone-producing tissues.

29 Dec 2010

Santarus, Pharming submit RHUCIN BLA to FDA for treatment of HAE attacks

Specialty biopharmaceutical company Santarus, Inc. and biotech company Pharming Group NV today announced the submission of a Biologics License Application (BLA) to the U.S. Food and Drug Administration (FDA) to obtain marketing approval for RHUCIN® (recombinant human C1 inhibitor) for the treatment of acute angioedema attacks in patients with Hereditary Angioedema (HAE).

29 Dec 2010

New Year's Eve can be bad for your health

Research has shown that New Year's is the deadliest day of the year for pedestrians. Drinking and walking can be as dangerous as drinking and driving. Trauma surgeon Dr. Thomas Esposito has seen the tragic effects of drunk walking, among his patients and in his own family.

29 Dec 2010

Exposure to persistent organic pollutants alters cortisol level in blood

Karin E Zimmer's PhD research shows that persistent organic pollutants (POPs), such as PCB and mixtures of different POPs, affect the way the adrenal cortex functions and thereby the synthesis of the stress hormone cortisol.

28 Dec 2010

Patients unresponsive to anti-anemia drug have higher risk of cardiovascular disease, death

Patients with diabetes, kidney disease and anemia who don't respond to treatment with an anti-anemia drug have a higher risk of cardiovascular disease or death, researchers at UT Southwestern Medical Center have found.

28 Dec 2010

HeartWare seeks FDA PMA approval for HeartWare Ventricular Assist System

HeartWare International, Inc. today announced that it has submitted a Pre-Market Approval (PMA) application to the U.S. Food and Drug Administration (FDA) for the HeartWare® Ventricular Assist System as a bridge to heart transplantation for patients with end-stage heart failure.

28 Dec 2010

Medical Condition News

Clinical Data closes sale of genetic, pharmacogenomic testing and biomarker development business

Dosing initiated in combination Phase I study of palifosfamide with etoposide and cisplatin/carboplatin in SCLC

Positive results from OMS201 Phase 1/2 trial in patients undergoing urologic procedures

CFTR protein regulates inflammation and cell death in emphysema, chronic lung diseases

New study reports close association between obesity and fibromyalgia

CEL-SCI initiates Multikine Phase III trail for head and neck cancer

Epilepsy more common than earlier thought: Study

Experimental device for obstructive sleep apnea

Controlling the amount of adipose tissue is key to combat obesity

Merck confirms plans for developing vernakalant drug for atrial fibrillation

New innovative program to identify and treat combat veterans suffering from PTSD

Florida Hospital, Sanford-Burnham and Takeda enter obesity research collaboration

Top weight-loss behaviors

Researchers develop breath-analysis technology for rapid detection of biomarkers

Kennedy Krieger inagurates new clinic for AHO treatment and research

Santarus, Pharming submit RHUCIN BLA to FDA for treatment of HAE attacks

New Year's Eve can be bad for your health

Exposure to persistent organic pollutants alters cortisol level in blood

Patients unresponsive to anti-anemia drug have higher risk of cardiovascular disease, death

HeartWare seeks FDA PMA approval for HeartWare Ventricular Assist System

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

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