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Mechanism that controls embryonic development could also prevent cancer

Researchers from Mount Sinai School of Medicine have identified a mechanism controlling the function of a protein that binds to DNA during embryonic development and may function to prevent abnormal tumor growth.

29 Oct 2010

GSK and Amicus announce Amigal development and commercialization agreement

GlaxoSmithKline PLC (GSK) and Amicus Therapeutics today announced a definitive agreement to develop and commercialize Amigal™ (migalastat HCl), currently in Phase 3 for the treatment of Fabry disease, a rare inherited disorder. Under the terms of the agreement, GSK will receive an exclusive worldwide license to develop, manufacture and commercialize migalastat HCl.

29 Oct 2010

Shire announces results of Vyvanse Phase 2 signal finding study for Major Depressive Disorder

Shire plc the global specialty biopharmaceutical company, today announced results from a Phase 2 signal finding study of Vyvanse(R) [lisdexamfetamine dimesylate (or SPD489)] in patients who have had residual symptoms of depression following treatment with LEXAPRO(escitlopram) for Major Depressive Disorder (MDD).

29 Oct 2010

Researchers analyze how sleep disorders affect risk perception in driving

Within the framework of a recent research project, University of Granada researchers will analyse how sleep disorders affect risk perception in driving. To such purpose, three last-generation simulators provided by the Faculty of Psychology will be employed.

29 Oct 2010

Pneumonia vaccination increases among older Americans, but still falls short of Healthy People 2010 goal

Between 2000 and 2007, the proportion of Americans age 65 and older who were vaccinated against pneumonia increased from 53 percent to 58 percent, but the rate fell far short of the Healthy People 2010 goal of 90 percent for pneumonia vaccinations in that age group, according to the latest News and Numbers from the Agency for Healthcare Research and Quality.

29 Oct 2010

Diabetic Hypoglycemia supports World Diabetes Day

Diabetic Hypoglycemia supports World Diabetes Day on the 14th November 2010 in raising the global awareness of diabetes ( http://www.worlddiabetesday.org/).

29 Oct 2010

New e-SMART-HD program helps improve doctor-patient communications

While many young adults will share the details of their daily lives with friends on Facebook, communicating with their doctors about mental illness is another story. E-SMART-MH, developed at Case Western Reserve University, might improve those communications.

29 Oct 2010

Novel small molecule inhibitors may provide new therapy for colon cancer

Researchers are one step closer to providing a new therapy for colon cancer, after findings revealed that a small molecule focal adhesion kinase (FAK) inhibitor known as Y15 effectively blocked cell viability, promoted detachment and apoptosis, and decreased tumor growth in mice. These findings were presented at the American Association for Cancer Research special conference on Colorectal Cancer: Biology to Therapy, held Oct. 27-30, 2010.

29 Oct 2010

Female soldiers at increased rates of developing PTSD following sexual trauma

Post-traumatic stress disorder, or PTSD, continues to inflict a mental and physical toll on America's soldiers, leaving physical, emotional and spiritual scars long after these veterans have left their posts in Iraq and Afghanistan. Additionally, for female soldiers, sexual assault and rape can create similar, and many times more treatment-resistant, symptoms of PTSD, according to Dr. Kimberly Dennis.

29 Oct 2010

Research on Rictor protein may provide new molecular target for cancer treatment

The discovery that a protein called Rictor plays a key role in destroying a close cousin of the AKT oncogene could provide scientists with a new molecular target for treating certain cancers, including breast cancer. Described in the September 2010 issue of the journal Molecular Cell, the study was led by scientists at Beth Israel Deaconess Medical Center (BIDMC).

29 Oct 2010

57% of ALK-positive advanced non-small cell lung cancer patients respond to crizotinib: Study

A study in the New England Journal of Medicine shows more than half of patients with a specific kind of lung cancer are responding positively to a treatment that targets the gene that drives their cancer.

29 Oct 2010

University of Maryland to establish major research enterprise for autoimmune diseases

With a new $45 million private gift from the family of a grateful patient, the University of Maryland School of Medicine is planning to establish the nation's only major research enterprise devoted to the study of autoimmune and inflammatory diseases such as celiac disease, multiple sclerosis, chronic obstructive pulmonary disease, asthma and Type 1 diabetes. The gift, from Indiana couple Ken and Shelia Cafferty, is the largest private donation in the history of the University System of Maryland.

29 Oct 2010

Eating disorders negatively affect oral health

While the connection between oral health and systemic health has been well-established, what most people don't know is that dentists often are in a position to detect systemic conditions. According to an article published in the October 2010 issue of AGD Impact, the monthly newsmagazine of the Academy of General Dentistry (AGD), dentists may be the first health care providers to notice evidence of an eating disorder, such as anorexia nervosa, bulimia nervosa, binge eating disorder, and pica.

29 Oct 2010

Pepsi Refresh grant helps in launching Rett syndrome drug development program

The International Rett Syndrome Foundation (IRSF) believes that accelerating the pace of meritorious research, supporting families, and raising awareness are the minimum effort necessary to successfully search for treatments and a cure for one of the most devastating neurological diseases to affect young girls. On October 1, IRSF became the recipient of a $250,000 grant from the Pepsi Refresh contest that was officially confirmed later in the month.

29 Oct 2010

New eight-month pilot program to advance standards of care for people with schizophrenia

The National Council for Community Behavioral Healthcare (National Council) today announced a new eight-month pilot program designed to advance standards of care for people living with schizophrenia. This initiative at 10 community behavioral health organizations nationwide is designed to improve the daily functioning of people with schizophrenia and raise expectations for what is achievable.

29 Oct 2010

LRI's innovative discovery to predict lupus receives license for clinical laboratory development

A discovery made by Lupus Research Institute-funded investigator Emily Baechler Gillespie, PhD, at the University of Minnesota has been licensed to a major clinical laboratory for development and could soon result in a test that quickly and easily enables patients and their physicians to determine when a lupus flare is imminent.

29 Oct 2010

Henry Ford Hospital physicist receives ASTRO's Basic Science Abstract Award

Henry Ford Hospital physicist Lei Ren, Ph.D., is among an elite group to be awarded for basic science research in radiation oncology at the 52nd annual American Society for Radiology Oncology (ASTRO) meeting in San Diego.

29 Oct 2010

ImmuneRegen's Homspera enhances survival of animals vaccinated with experimental melanoma vaccine

ImmuneRegen BioSciences, Inc.®, a wholly owned subsidiary of IR BioSciences Holdings, Inc., today announced that treatment with its lead compound, Homspera®, improved the survival of animals vaccinated with an experimental melanoma vaccine.

29 Oct 2010

Study finds genetic variants that may modify breast cancer risk among women with BRCA2 mutation

An international study led by researchers at Memorial Sloan-Kettering Cancer Center has identified genetic variants in women with BRCA2 mutations that may increase or decrease their risk of developing breast cancer. The study was published today online in the open-access journal PLoS Genetics.

29 Oct 2010

Fast Neutron Radiotherapy safe and effective for treatment of non-small cell lung cancer: Study

Scientists from the Barbara Ann Karmanos Cancer Institute and Wayne State University School of Medicine (WSU SOM) in Detroit are presenting two research studies that found the use of Fast Neutron Radiotherapy (FNRT) – a form of radiation that is about three times more powerful than typical photon radiotherapy – is highly effective and safe for patients who are dealing with non-small cell lung cancer. The findings are being formally presented Monday, Nov. 1, at the American Society of Therapeutic Radiology and Oncology (ASTRO) Annual Meeting.

29 Oct 2010

Medical Condition News

Mechanism that controls embryonic development could also prevent cancer

GSK and Amicus announce Amigal development and commercialization agreement

Shire announces results of Vyvanse Phase 2 signal finding study for Major Depressive Disorder

Researchers analyze how sleep disorders affect risk perception in driving

Pneumonia vaccination increases among older Americans, but still falls short of Healthy People 2010 goal

Diabetic Hypoglycemia supports World Diabetes Day

New e-SMART-HD program helps improve doctor-patient communications

Novel small molecule inhibitors may provide new therapy for colon cancer

Female soldiers at increased rates of developing PTSD following sexual trauma

Research on Rictor protein may provide new molecular target for cancer treatment

57% of ALK-positive advanced non-small cell lung cancer patients respond to crizotinib: Study

University of Maryland to establish major research enterprise for autoimmune diseases

Eating disorders negatively affect oral health

Pepsi Refresh grant helps in launching Rett syndrome drug development program

New eight-month pilot program to advance standards of care for people with schizophrenia

LRI's innovative discovery to predict lupus receives license for clinical laboratory development

Henry Ford Hospital physicist receives ASTRO's Basic Science Abstract Award

ImmuneRegen's Homspera enhances survival of animals vaccinated with experimental melanoma vaccine

Study finds genetic variants that may modify breast cancer risk among women with BRCA2 mutation

Fast Neutron Radiotherapy safe and effective for treatment of non-small cell lung cancer: Study

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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